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pro vyhledávání: '"Shawn Donald Johnstone"'
Autor:
Dean G. Brown, Wenzhen Yang, Rongfeng Chen, Shawn Donald Johnstone, Maria Fridén-Saxin, Stefan Geschwindner, Anneli Nordqvist, Junxian Lim, Linda Sundström, Yuhong Jiang, Qingqi Liu, David P. Fairlie, Rob Cooke, Andrew Madin, Rink-Jan Lohman, Amanda J. Kennedy, Eunice K. Y. Poon, Niek Dekker
Publikováno v:
Communications Biology, Vol 3, Iss 1, Pp 1-13 (2020)
Communications Biology
Communications Biology
Protease-activated receptor-2 (PAR2) has been implicated in multiple pathophysiologies but drug discovery is challenging due to low small molecule tractability and a complex activation mechanism. Here we report the pharmacological profiling of a pote