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pro vyhledávání: '"Shawn D. Lade"'
Autor:
Amanda K. Charlton-Sevcik, Lindsey K. Snyder, Audra Johansen, Lindsay M. Jones, Shawn D. Lade, Liela Bayeh, Jiangli Song, Gustavo E. Chavarria, Mary Lynn Trawick, David J. Chaplin, Victoria Soeung, Kevin G. Pinney, Adam Jantz
Publikováno v:
Bioorganicmedicinal chemistry letters. 23(9)
Cathepsin L is a cysteine protease that is upregulated in a variety of malignant tumors and plays a significant role in cancer cell invasion and migration. It is an attractive target for the development of small-molecule inhibitors, which may prove b