Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Shawn A. Gannon"'
Autor:
Vamsi K Kodali, Shawn A Gannon, Sivakumar Paramasivam, Sonali Raje, Tatyana Polenova, Colin Thorpe
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18187 (2011)
Under the shell of a chicken egg are two opposed proteinaceous disulfide-rich membranes. They are fabricated in the avian oviduct using fibers formed from proteins that are extensively coupled by irreversible lysine-derived crosslinks. The intractabi
Externí odkaz:
https://doaj.org/article/71e728db77af43bf8042972158707aa5
Publikováno v:
Birth Defects Research. 109:1301-1304
Background Cervical ribs in rat fetuses have been widely reported to occur in controls as well as in response to various maternal chemical exposures. However, few evaluations of cervical ribs have been reported in rats postnatally. The available lite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07521e79129000fdbc05d60f0e499e1c
https://doi.org/10.1002/bdr2.1090
https://doi.org/10.1002/bdr2.1090
Publikováno v:
Free Radical Biology and Medicine. 80:171-182
This review examines oxidative protein folding within the mammalian endoplasmic reticulum (ER) from an enzymological perspective. In protein disulfide isomerase-first (PDI-first) pathways of oxidative protein folding, PDI is the immediate oxidant of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de18e85cf5a56245bd1d8d342a1522e1
https://doi.org/10.1016/j.freeradbiomed.2014.07.037
https://doi.org/10.1016/j.freeradbiomed.2014.07.037
Publikováno v:
Free Radical Biology and Medicine. 69:129-135
A sensitive new plate reader assay has been developed showing that adult mammalian blood serum contains circulating soluble sulfhydryl oxidase activity that can introduce disulfide bonds into reduced proteins with the reduction of oxygen to hydrogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cee10d95f564dfe723d9fe9fe3466f41
https://doi.org/10.1016/j.freeradbiomed.2014.01.020
https://doi.org/10.1016/j.freeradbiomed.2014.01.020
Publikováno v:
Biochemistry. 52:8323-8332
Augmenter of liver regeneration is a member of the ERV family of small flavin-dependent sulfhydryl oxidases that contain a redox-active CxxC disulfide bond in redox communication with the isoalloxazine ring of bound FAD. These enzymes catalyze the ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6838d4a21e88bd1ced89921ef920eb
https://doi.org/10.1021/bi401305w
https://doi.org/10.1021/bi401305w
Autor:
Shawn A. Gannon, Diane L. Nabb, Tessa L. Serex, Scott E. Loveless, Terry L. Johnson, Robert C. Buck
Publikováno v:
Toxicology. 283:55-62
The absorption, tissue distribution, elimination, and metabolism of [1-¹⁴C]-PFHx in rats and mice dosed orally at 2 or 100 mg/kg was evaluated following a single dose or after 14 consecutive doses. Absorption was rapid in rats as evidenced by a sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43a008c001dc9bdd0382a835c2d2b3dc
https://doi.org/10.1016/j.tox.2011.02.004
https://doi.org/10.1016/j.tox.2011.02.004
Publikováno v:
Drug Metabolism and Disposition. 34:1019-1029
Geranyl nitrile (GN) and citronellyl nitrile (CN) are fragrance components used in consumer and personal care products. Differences in the clastogenicity of these two terpenes are postulated to result from differential biotransformation, presumably i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e208807063ede0dd6993539bcee648c
https://doi.org/10.1124/dmd.105.005496
https://doi.org/10.1124/dmd.105.005496
Publikováno v:
Toxicology. 211:139-148
This study was conducted to develop a quantitative understanding of the potential for gestational and lactational transfer of perfluorooctanoate (PFOA) in the rat. Time-mated female rats were dosed by oral gavage once daily at concentrations of 3, 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04f0895486c1ac5924044f5adba6bcf
https://doi.org/10.1016/j.tox.2005.03.010
https://doi.org/10.1016/j.tox.2005.03.010
Autor:
Ching-Hui Yang, Bogdan Szostek, Robert T. Mingoia, Diane L. Nabb, Gary W. Jepson, Xing Han, Matthew W. Himmelstein, Steve F. Cheatham, Shawn A. Gannon
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 39(7)
In vitro metabolism of 1,2,3,3,3-pentafluoropropene (PFP) was investigated in the present study. PFP was metabolized via cytochrome P450-catalyzed oxidative dehalogenation in liver microsomes and glutathione transferase (GST)-catalyzed conjugation in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e6581c742fe7e36f2944801610ad88
https://pubmed.ncbi.nlm.nih.gov/21493824
https://pubmed.ncbi.nlm.nih.gov/21493824
Autor:
Shawn A, Gannon, Terry, Johnson, Diane L, Nabb, Tessa L, Serex, Robert C, Buck, Scott E, Loveless
Publikováno v:
Toxicology. 283(1)
The absorption, tissue distribution, elimination, and metabolism of [1-¹⁴C]-PFHx in rats and mice dosed orally at 2 or 100 mg/kg was evaluated following a single dose or after 14 consecutive doses. Absorption was rapid in rats as evidenced by a sh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ac255119dd1584c83d0af9252dbf846
https://pubmed.ncbi.nlm.nih.gov/21349313
https://pubmed.ncbi.nlm.nih.gov/21349313