Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Shawn, Zhang"'
Autor:
Timothy Hornick, Chen Mao, Athanas Koynov, Phillip Yawman, Prajwal Thool, Karthik Salish, Morgan Giles, Karthik Nagapudi, Shawn Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Pharmaceutical drug dosage forms are critical for ensuring the effective and safe delivery of active pharmaceutical ingredients to patients. However, traditional formulation development often relies on extensive lab and animal experimentatio
Externí odkaz:
https://doaj.org/article/122df0be99494ec1984704ffcbb68658
Autor:
Andrew G. Clark, Ruifeng Wang, Josh Lomeo, Yan Wang, Aiden Zhu, Mike Shen, Quanying Bao, Diane J. Burgess, Bin Qin, Shawn Zhang
Publikováno v:
Journal of Controlled Release. 358:626-635
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45a033250dcc581bd05d823bca2751de
https://doi.org/10.1016/j.jconrel.2023.05.019
https://doi.org/10.1016/j.jconrel.2023.05.019
Publikováno v:
Journal of Pharmaceutical Sciences. 112:1625-1634
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d150aa15bf5ecfef8cb1100a2a3aec76
https://doi.org/10.1016/j.xphs.2023.01.002
https://doi.org/10.1016/j.xphs.2023.01.002
Autor:
Shawn Zhang, Karthik Nagapudi, Mike Shen, Joshua Lomeo, Yuri Qin, Aiden Zhu, Purnendu Nayak, Debby Chang, Rami N. Hannoush
Publikováno v:
Journal of Pharmaceutical Sciences. 111:1896-1910
The development of long-acting drug formulations requires efficient characterization technique as the designed 6-12 months release duration renders real-time in vitro and in vivo experiments cost and time prohibitive. Using a novel image-based releas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac56ac1b9c016d9b1618b73a6dc60669
https://doi.org/10.1016/j.xphs.2021.12.009
https://doi.org/10.1016/j.xphs.2021.12.009
Autor:
Wei Jia, Phillip D. Yawman, Keyur M. Pandya, Kellie Sluga, Tania Ng, Dawen Kou, Karthik Nagapudi, Paul E. Luner, Aiden Zhu, Shawn Zhang, Hao Helen Hou
Publikováno v:
Pharmaceutical Research. 39:3137-3154
The purpose of this work is to evaluate the interrelationship of microstructure, properties, and dissolution performance for amorphous solid dispersions (ASDs) prepared using different methods.ASD of GDC-0810 (50% w/w) with HPMC-AS was prepared using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e731878341a27a4bc00f86ef93b51c5b
https://doi.org/10.1007/s11095-022-03308-9
https://doi.org/10.1007/s11095-022-03308-9
Autor:
Lillian Skidmore, David Mills, Ji Young Kim, Prathap Shastri, Nick A. Knudsen, Jeff Steen, Jay Nelson, Ying Buechler, Feng Tian, Shawn Zhang
Publikováno v:
Cancer Research. 83:3997-3997
Prostate cancer is the most common cancer, and the second leading cause of cancer death, among men in the United States. Metastatic castration-resistant prostate cancer (mCRPC) is an advanced stage of disease in which patients ultimately fail androge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b9fb9bee3440d6938bcee16c385557e
https://doi.org/10.1158/1538-7445.am2023-3997
https://doi.org/10.1158/1538-7445.am2023-3997
Publikováno v:
Microscopy and Microanalysis. 26:2862-2865
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea6719d1af2955f27daf46401e455fe3
https://doi.org/10.1017/s143192762002303x
https://doi.org/10.1017/s143192762002303x
Publikováno v:
The AAPS Journal. 24
This work reports the use of X-ray microscopy (XRM) imaging to characterize the microstructure of semisolid formulations containing multiple immiscible phases. For emulsion-based semisolid formulations, the disperse phase globule size and its distrib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fdf659d9b78078ef0a408bd4a40bf79
https://doi.org/10.1208/s12248-022-00696-z
https://doi.org/10.1208/s12248-022-00696-z
Autor:
Andrew G. Clark, Ruifeng Wang, Yuri Qin, Yan Wang, Aiden Zhu, Joshua Lomeo, Quanying Bao, Diane J. Burgess, Jacie Chen, Bin Qin, Yuan Zou, Shawn Zhang
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 349
The distribution of the active pharmaceutical ingredient (API) within polymer-based controlled release drug products is a critical quality attribute (CQA). It is crucial for the development of such products, to be able to accurately characterize phas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f00c999d3b7607aa7a81be4e541c8ee4
https://pubmed.ncbi.nlm.nih.gov/35803326
https://pubmed.ncbi.nlm.nih.gov/35803326
Publikováno v:
Powder Technology. 417:118273
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69876345fdaa8fc8ae1c67fa97b37782
https://doi.org/10.1016/j.powtec.2023.118273
https://doi.org/10.1016/j.powtec.2023.118273