Multivariate metabotyping of plasma accurately predicts survival in patients with decompensated cirrhosis

Autor: McPhail, Mark, Shawcross, Deborah Lindsay, Lewis, Matthew R., Coltart, Iona, Want, Elizabeth J, Antoniades, Charalambos G, Veselkov, Kiril, Triantafyllou, Evangelos, Patel, Vishal C., Pop, Oltin T, Gomez-Romero, Maria, Kyriakides, Michael, Zia, Rabiya, Abeles, Robin Daniel, Crossey, Mary M E, Jassem, Wayel, O'Grady, John, Heaton, Nigel, Auzinger, Georg, Bernal, William, Quaglia, Alberto, Coen, Muireann, Nicholson, Jeremy K., Wendon, Julia Alexis, Holmes, Elaine, Taylor-Robinson, Simon D.

Publikováno v: McPhail, M, Shawcross, D L, Lewis, M R, Coltart, I, Want, E J, Antoniades, C G, Veselkov, K, Triantafyllou, E, Patel, V C, Pop, O T, Gomez-Romero, M, Kyriakides, M, Zia, R, Abeles, R D, Crossey, M M E, Jassem, W, O'Grady, J, Heaton, N, Auzinger, G, Bernal, W, Quaglia, A, Coen, M, Nicholson, J K, Wendon, J A, Holmes, E & Taylor-Robinson, S D 2016, ' Multivariate metabotyping of plasma accurately predicts survival in patients with decompensated cirrhosis. ', Journal of Hepatology, vol. 64, no. 5, pp. 1058-1067 . https://doi.org/10.1016/j.jhep.2016.01.003

BACKGROUND AND AIMS: Predicting survival in decompensated cirrhosis (DC) is important in decision making for liver transplantation and resource allocation. We investigated whether high-resolution metabolic profiling can determine a metabolic phenotyp

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https://kclpure.kcl.ac.uk/ws/files/95133944/Multivariate_metabotyping_of_plasma_MCPHAIL_Firstonline18January2016_GOLD_VoR_CC_BY_.pdf