Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Shaw-Guang Lee"'
Autor:
Mark S. Wade, Bheem M. Bhat, Surendra K. Dheer, Pranab K. Chanda, Ramesh A. Bhat, Michael D. Lubeck, Shaw-Guang Lee, Shridhara Murthy, Jorg W. Eichberg, Paul P. Hung, Krishna K. Murthy, Murty Chengalvala, Alan R. Davis, Robert J. Natuk, Satoshi Mizutani
Publikováno v:
AIDS Research and Human Retroviruses. 10:1443-1449
Recombinant adenovirus (Ad)-human immunodeficiency virus (HIV) vaccines expressing HIVIIIB Env and Gag proteins were evaluated for immunogenicity in chimpanzees following intranasal administration. When Ad7-, Ad4-, and Ad5-vectored vaccines were admi
Autor:
Steven K. Vernon, James M. Wilhelm, Mark S. Wade, Pranab K. Chanda, R J Natuk, Shaw-Guang Lee, Shridhara Murthy, Jorg W. Eichberg, Michael D. Lubeck, Krishna K. Murthy, Satoshi Mizutani, Paul P. Hung, Alan R. Davis, Surendra K. Dheer, Murty Chengalvala
Publikováno v:
AIDS Research and Human Retroviruses. 9:395-404
Recombinant human adenovirus (Ad) type 4-, 5-, and 7-vectored vaccines expressing either the HIV env or gag-protease genes were tested for immunogenicity in three chimpanzees. The first phase of the vaccination protocol consisted of a primary and two
Autor:
Alan R. Davis, Satoshi Mizutani, Michael D. Lubeck, Murty Chengalvala, Wei Wei Ye, Shaw-Guang Lee, B. B. Mason, G. Zandle, Paul P. Hung, Sheau-Mei Cheng
Publikováno v:
Archives of Virology. 118:11-27
Adenovirus type 7 vaccine strain was engineered to express foreign antigens from both the E 3 early promoter in the E 3 region and the major late promoter inserted between the E 4 region and the right inverted terminal repeat. This multiple expressio
Autor:
Sheau-Mei Cheng, Vanessa M. Hirsch, Paul P. Hung, Shaw-Guang Lee, Philip R. Johnson, Marlene Blume
Publikováno v:
Virology. 177:816-819
The coexpression of biologically active simian immunodeficiency virus (SIV) Rev and Env gene products was obtained in COS-1 cells from a single SIV subgenomic segment (which contains both exons of rev and the entire env gene) cloned into a SV40-direc
Autor:
Vanessa M. Hirsch, Sheau-Mei Cheng, Shaw-Guang Lee, Paul P. Hung, Marlene Blume, Philip R. Johnson
Publikováno v:
Journal of Medical Primatology. 19:167-176
The rev gene product is a trans-acting nuclear regulatory protein that is essential for AIDS virus replication. To define the effect of the SIV rev gene on its gp160 expression, two SV40 constructs have been made: pBC17 is a rev+env+ construct, and p
Autor:
S. M. Cheng, F. Wiener, P. P. Hung, N.K. Kalyan, S.K. Dheer, Shaw Guang Lee, W.A. Pierzchala, J. Wilhelm, R. Hjorth
Publikováno v:
Fibrinolysis. 4:79-86
A DNA sequence coding for the second kringle of tissue-type plasminogen activator (t-PA) was synthesised chemically and inserted just before the double-kringle region of the t-PA gene. This tris-kringle PA or hybrid F gene was expressed in a BPV-base
Autor:
James Wilhelm, Shaw Guang Lee, Narender K. Kalyan, Paul P. Hung, Wah-Tung Hum, Ruth S Rappaport
Publikováno v:
Thrombosis and Haemostasis. 63:464-471
SummaryΔ2−89 t-PA is a deletion mutant lacking the finger (F) and epidermal growth factor (EGF) domains; thus, the fibrin interaction of this molecule must be mediated solely by the kringle region. In the present study, the influence of the oligos
Autor:
Paul P. Hung, Alan R. Davis, Michael R. Pisano, Jorg W. Eichberg, Shaw-Guang Lee, Narender K. Kalyan, Marjorie Robert-Guroff, Wah-Tung Hum, Chu-Lai Hsiao, James M. Wilhelm
Publikováno v:
Vaccine. 12(8)
Haemagglutinin (HA), the major surface glycoprotein of influenza virus, is a potent immunogen against which viral neutralizing antibodies are directed. Studies of the three-dimensional structure of HA have identified major antigenic sites on the mole
Autor:
M D Lubeck, B M Bhat, Shaw-Guang Lee, J Wilhelm, R Hjorth, Satoshi Mizutani, Alan R. Davis, P K Chanda, M S Wade, R J Natuk
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 89(16)
Recombinant human adenoviruses (Ads) (types 4, 5, and 7) expressing the HIV-1 envelope membrane glycoprotein (gp160) were tested for immunogenicity in the dog. Administration of recombinant Ad7-env by intratracheal inoculation resulted in a low serum
Autor:
Pranab K. Chanda, Steven K. Vernon, James M. Wilhelm, Paul P. Hung, Shridhara Murthy, Narender K. Kalyan, Shaw-Guang Lee
Publikováno v:
The Journal of general virology. 72
The human immunodeficiency virus type 1 (HIV-1) Gag protein was expressed in A549 cells infected with recombinant adenovirus types 4 and 7, each carrying the HIV-1 gag and pro genes. The Gag protein was assembled into enveloped virus-like particles t