Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Shaw Min Hou"'
1
Akademický článek
Myricetin as a promising inhibitor of platelet fibrinogen receptor in humans
Autor: Yi Chang, Chih-Wei Hsia, Wei-Chieh Huang, Thanasekaran Jayakumar, Chih-Hsuan Hsia, Ting-Lin Yen, Joen-Rong Sheu, Shaw-Min Hou
Publikováno v: Heliyon, Vol 9, Iss 10, Pp e20286- (2023)
Platelets play a vital role in the formation of dangerous arterial thrombosis. Platelets are activated by adhesive proteins or soluble agonists through their specific receptors. The receptor-mediated signaling pathways lead to common signaling events
Externí odkaz: https://doaj.org/article/6afe699405ae4e828d1494bec7b1eece
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2
Akademický článek
Modulation of human platelet activation and in vivo vascular thrombosis by columbianadin: regulation by integrin αIIbβ3 inside-out but not outside-in signals
Autor: Shaw-Min Hou, Chih-Wei Hsia, Cheng-Lin Tsai, Chih-Hsuan Hsia, Thanasekaran Jayakumar, Marappan Velusamy, Joen-Rong Sheu
Publikováno v: Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-14 (2020)
Abstract Background Columbianadin (CBN) is one of the main coumarin constituents isolated from Angelica pubescens. The pharmacological value of CBN is well demonstrated, especially in the prevention of several cancers and analgesic activity. A striki
Externí odkaz: https://doaj.org/article/a95805c688424ed388ae9b7600b23f2f
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3
Akademický článek
Decreased Human Platelet Activation and Mouse Pulmonary Thrombosis by Rutaecarpine and Comparison of the Relative Effectiveness with BAY11-7082: Crucial Signals of p38-NF-κB
Autor: Wei-Chieh Huang, Shaw-Min Hou, Ming-Ping Wu, Chih-Wei Hsia, Thanasekaran Jayakumar, Chih-Hsuan Hsia, Periyakali Saravana Bhavan, Chi-Li Chung, Joen-Rong Sheu
Publikováno v: Molecules, Vol 27, Iss 2, p 476 (2022)
Platelets play a critical role in arterial thrombosis. Rutaecarpine (RUT) was purified from Tetradium ruticarpum, a well-known Chinese medicine. This study examined the relative activity of RUT with NF-κB inhibitors in human platelets. BAY11-7082 (a
Externí odkaz: https://doaj.org/article/bf18384d6c4d40eb9a4471f83b07b83c
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4
Akademický článek
Columbianadin Dampens In Vitro Inflammatory Actions and Inhibits Liver Injury via Inhibition of NF-κB/MAPKs: Impacts on ∙OH Radicals and HO-1 Expression
Autor: Thanasekaran Jayakumar, Shaw-Min Hou, Chao-Chien Chang, Tsorng-Harn Fong, Chih-Wei Hsia, Yen-Jen Chen, Wei-Chieh Huang, Periyakali Saravanabhavan, Manjunath Manubolu, Joen-Rong Sheu, Chih-Hsuan Hsia
Publikováno v: Antioxidants, Vol 10, Iss 4, p 553 (2021)
Columbianadin (CBN), a natural coumarin isolated from Angelica decursiva, is reported to have numerous biological activities, including anticancer and platelet aggregation inhibiting properties. Here, we investigated CBN’s anti-inflammatory effect
Externí odkaz: https://doaj.org/article/1a15f331b487477cb035a33ce3f27b3d
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6
Glabridin, a Bioactive Flavonoid from Licorice, Effectively Inhibits Platelet Activation in Humans and Mice
Autor: Chi-Li Chung, Jui-Hsuan Chen, Wei-Chieh Huang, Joen-Rong Sheu, Chih-Wei Hsia, Thanasekaran Jayakumar, Chih-Hsuan Hsia, Kuan-Rau Chiou, Shaw-Min Hou
Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11372
Platelets are crucial for hemostasis and arterial thrombosis, which may lead to severe cardiovascular diseases (CVDs). Thus, therapeutic agents must be developed to prevent pathological platelet activation. Glabridin, a major bioalkaloid extracted fr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1518b2e099829a2ea50734733d496d3
https://pubmed.ncbi.nlm.nih.gov/36232674
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7
Columbianadin Dampens In Vitro Inflammatory Actions and Inhibits Liver Injury via Inhibition of NF-κB/MAPKs: Impacts on ∙OH Radicals and HO-1 Expression
Autor: Chih Wei Hsia, Shaw Min Hou, Chih Hsuan Hsia, Manjunath Manubolu, Yen Jen Chen, Thanasekaran Jayakumar, Joen Rong Sheu, Tsorng Harn Fong, Wei-Chieh Huang, Chao Chien Chang, Periyakali Saravanabhavan
Publikováno v: Antioxidants
Antioxidants, Vol 10, Iss 553, p 553 (2021)
Volume 10
Issue 4
Columbianadin (CBN), a natural coumarin isolated from Angelica decursiva, is reported to have numerous biological activities, including anticancer and platelet aggregation inhibiting properties. Here, we investigated CBN’s anti-inflammatory effect
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fad524cef52111ba0eee6abc31d717d9
http://europepmc.org/articles/PMC8067002
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8
The Antithrombotic Agent Pterostilbene Interferes with Integrin αIIbβ3-Mediated Inside-Out and Outside-In Signals in Human Platelets
Autor: Periyakali Saravana Bhavan, Ting Yu Chen, Chih-Wei Hsia, Joen Rong Sheu, Chih-Hsuan Hsia, Kao-Chang Lin, Shaw-Min Hou, Wei-Chieh Huang
Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 3643, p 3643 (2021)
Volume 22
Issue 7
Platelets play a crucial role in the physiology of primary hemostasis and pathological processes such as arterial thrombosis
thus, developing a therapeutic target that prevents platelet activation can reduce arterial thrombosis. Pterostilbene (P
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93f762978ce5e9ca0080d044561c7927
http://europepmc.org/articles/PMC8037547
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9
Modulation of human platelet activation and in vivo vascular thrombosis by columbianadin: regulation by integrin αIIbβ3 inside-out but not outside-in signals
Autor: Marappan Velusamy, Thanasekaran Jayakumar, Joen Rong Sheu, Chih Wei Hsia, Chih Hsuan Hsia, Cheng Lin Tsai, Shaw Min Hou
Publikováno v: Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-14 (2020)
Background Columbianadin (CBN) is one of the main coumarin constituents isolated from Angelica pubescens. The pharmacological value of CBN is well demonstrated, especially in the prevention of several cancers and analgesic activity. A striking therap
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3067cfe875fb728cf2d19db8c057bf1
https://doi.org/10.1186/s12929-020-0619-5
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10
Mitral valve repair versus replacement in patients with ischemic mitral regurgitation
Autor: Meng Lin Lee, Thay-Hsiung Chen, Hsien Da Huang, Shaw-Min Hou
Publikováno v: Journal of Thoracic Disease. 10:2820-2828
Background: The optimal management of ischemic mitral regurgitation (IMR) is controversial. The aim of this study was to examine our eight years’ experience of surgical treatment in patients with IMR, and to compare outcomes of mitral valve repair
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6590999218eb942b08bd0757af5ec8
https://doi.org/10.21037/jtd.2018.04.93
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