Preimplantation genetic testing (PGT) for copy number variants of uncertain significance (CNV- VUS) in the genomic era: to do or not to do?

Autor: Rotshenker-Olshinka K; Reproductive Endocrinology and Genetics Unit, IVF Unit, Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Jerusalem, Israel. Kerenlogic@gmail.com.; Faculty of Medicine, Hebrew University, Jerusalem, Israel. Kerenlogic@gmail.com.; Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology and Infertility, McGill University, Montréal, Quebec, H3A 0G4, Canada. Kerenlogic@gmail.com., Srebnik Moshe N; Reproductive Endocrinology and Genetics Unit, IVF Unit, Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Jerusalem, Israel.; Faculty of Medicine, Hebrew University, Jerusalem, Israel., Weiss O; Faculty of Medicine, Hebrew University, Jerusalem, Israel.; Medical Genetics Institute, Shaare Zedek Medical Center, Jerusalem, Israel., Shaviv S; Faculty of Medicine, Hebrew University, Jerusalem, Israel.; ZOHAR PGD Unit, Medical Genetics Institute, Shaare Zedek Medical Center, Jerusalem, Israel., Freireich O; Faculty of Medicine, Hebrew University, Jerusalem, Israel.; ZOHAR PGD Unit, Medical Genetics Institute, Shaare Zedek Medical Center, Jerusalem, Israel., Segel R; Faculty of Medicine, Hebrew University, Jerusalem, Israel.; ZOHAR PGD Unit, Medical Genetics Institute, Shaare Zedek Medical Center, Jerusalem, Israel., Zeligson S; Faculty of Medicine, Hebrew University, Jerusalem, Israel.; ZOHAR PGD Unit, Medical Genetics Institute, Shaare Zedek Medical Center, Jerusalem, Israel., Eldar-Geva T; Reproductive Endocrinology and Genetics Unit, IVF Unit, Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Jerusalem, Israel.; Faculty of Medicine, Hebrew University, Jerusalem, Israel., Altarescu G; Faculty of Medicine, Hebrew University, Jerusalem, Israel.; ZOHAR PGD Unit, Medical Genetics Institute, Shaare Zedek Medical Center, Jerusalem, Israel.

Publikováno v: Journal of assisted reproduction and genetics [J Assist Reprod Genet] 2021 Mar; Vol. 38 (3), pp. 719-725. Date of Electronic Publication: 2021 Jan 14.

49. Molecular PGT-M for VUS in the genomic era: to do or not to do?

Autor: Rotshenker Olshinka, K., Weiss, O., Srebnik, N., Shaviv, S., Freireich, O., Segel, R., Geva, T. Eldar, Altarescu, G.

Publikováno v: In Reproductive BioMedicine Online August 2019 39 Supplement 1:e56-e57

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