Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Shaunna M. Huston"'
Autor:
Henry Ogbomo, Martina Timm-McCann, Tavish Barnes, Richard F. Xiang, Khusraw Jamil, Anutosh Ganguly, Danuta Stack, Shaunna M. Huston, Shu Shun Li, Pina Colarusso, Christopher H. Mody
Publikováno v:
Cell Reports, Vol 24, Iss 11, Pp 3017-3032 (2018)
Summary: Cryptococcus is the most important cause of fungal meningitis in immunocompromised individuals. Host defense against Cryptococcus involves direct killing by NK cells. That NK cells from HIV-infected patients fail to polarize perforin to the
Externí odkaz:
https://doaj.org/article/ca9f21426ae948e5b6e639613c33ec38
Autor:
Stephen K. Kyei, Henry Ogbomo, ShuShun Li, Martina Timm-McCann, Richard F. Xiang, Shaunna M. Huston, Anutosh Ganguly, Pina Colarusso, M. John Gill, Christopher H. Mody
Publikováno v:
mBio, Vol 7, Iss 4 (2016)
ABSTRACT Cryptococcus neoformans is a pathogenic yeast and a leading cause of life-threatening meningitis in AIDS patients. Natural killer (NK) cells are important immune effector cells that directly recognize and kill C. neoformans via a perforin-de
Externí odkaz:
https://doaj.org/article/a2b036e8e6a841d786731795eccab039
Autor:
Tavish Barnes, Danuta Stack, Richard F. Xiang, Henry Ogbomo, Pina Colarusso, Christopher H. Mody, Anutosh Ganguly, Shaunna M. Huston, Martina Timm-McCann, Khusraw Jamil, Shu Shun Li
Publikováno v:
Cell Reports, Vol 24, Iss 11, Pp 3017-3032 (2018)
Summary: Cryptococcus is the most important cause of fungal meningitis in immunocompromised individuals. Host defense against Cryptococcus involves direct killing by NK cells. That NK cells from HIV-infected patients fail to polarize perforin to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d29912d980a0312b16cf7c90e0dd7044
https://doi.org/10.1016/j.celrep.2018.08.027
https://doi.org/10.1016/j.celrep.2018.08.027
Publikováno v:
Clinics in Chest Medicine. 38:451-464
Cryptococcus is among the most common invasive fungal pathogens globally and is one of the leading causes of acquired immunodeficiency virus-related deaths. Cryptococcus neoformans and Cryptococcus gattii are the most clinically relevant species and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c7dec2011a07d0a6a5908198486c71
https://doi.org/10.1016/j.ccm.2017.04.007
https://doi.org/10.1016/j.ccm.2017.04.007
Autor:
Danuta Stack, Stephen K. Kyei, Richard F. Xiang, Shaunna M. Huston, Christopher H. Mody, Shu Shun Li, Henry Ogbomo
Publikováno v:
Journal of Biological Chemistry. 291:6912-6922
The activity of Rac in leukocytes is essential for immunity. However, its role in NK cell-mediated anti-microbial signaling remains unclear. In this study, we investigated the role of Rac in NK cell mediated anti-cryptococcal killing. We found that C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f722544745ac56d20b1910f4c4e18e7
https://doi.org/10.1074/jbc.m115.681544
https://doi.org/10.1074/jbc.m115.681544
Autor:
Christopher H. Mody, Shaunna M. Huston, Byron M. Berenger, Shu Shun Li, Anowara Islam, Martina Timm-McCann, Danuta Stack, Gareth Jones, Richard F. Xiang, Pina Colarusso
Publikováno v:
The Journal of Immunology. 191:249-261
During adaptive immunity to pathogens, dendritic cells (DCs) capture, kill, process, and present microbial Ags to T cells. Ag presentation is accompanied by DC maturation driven by appropriate costimulatory signals. However, current understanding of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3673167647e47685e75cfd554c83837e
https://doi.org/10.4049/jimmunol.1202707
https://doi.org/10.4049/jimmunol.1202707
Autor:
M. John Gill, Martina Timm-McCann, Christopher H. Mody, Henry Ogbomo, Richard F. Xiang, Pina Colarusso, Shaunna M. Huston, Stephen K. Kyei, Shu Shun Li, Anutosh Ganguly
Publikováno v:
mBio, Vol 7, Iss 4, p e00878-16 (2016)
mBio
mBio, Vol 7, Iss 4 (2016)
mBio
mBio, Vol 7, Iss 4 (2016)
Cryptococcus neoformans is a pathogenic yeast and a leading cause of life-threatening meningitis in AIDS patients. Natural killer (NK) cells are important immune effector cells that directly recognize and kill C. neoformans via a perforin-dependent c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c580b26c74ea352354e814e318c9fa61
http://mbio.asm.org/cgi/content/full/7/4/e00878-16
http://mbio.asm.org/cgi/content/full/7/4/e00878-16
Publikováno v:
Canadian Medical Association Journal. 184:1387-1390
A 27-year-old previously healthy woman presented to the emergency department in Calgary, Alberta, with shortness of breath, muscle aches and a nonproductive cough that had lasted for 48 hours. During the previous two weeks, the patient had experience
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::823bf14a60b0fa6d8e3960e8ec8ff605
https://doi.org/10.1503/cmaj.111346
https://doi.org/10.1503/cmaj.111346
Autor:
Chunfu Zheng, M. John Gill, Meiqing Shi, Shaunna M. Huston, Christopher H. Mody, Alan M. Krensky, Gareth Jones, Byron M. Berenger, Kaleb J. Marr, Paul Kubes, Jeremy C. D. Wiseman
Publikováno v:
The Journal of Immunology. 180:7221-7229
Granulysin is a cytolytic effector molecule used by lymphocytes to kill tumor and microbial cells. Regulation of granulysin production is complex. A significant delay (5 days) following stimulation of CD4+ T cells with IL-2 occurs before granulysin i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39cf0605e35f7e838bbfef4fe3bc292
https://doi.org/10.4049/jimmunol.180.11.7221
https://doi.org/10.4049/jimmunol.180.11.7221
Autor:
Paul Oykhman, Shaunna M. Huston, Martina Timm-McCann, Danuta Stack, Henry Ogbomo, Christopher H. Mody, Popchai Ngamskulrungroj, Richard F. Xiang, Shu Shun Li, Stephen K. Kyei, Kyung J. Kwon-Chung
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 196(3)
Cryptococcus gattii is an emerging fungal pathogen on the west coast of Canada and the United States that causes a potentially fatal infection in otherwise healthy individuals. In previous investigations of the mechanisms by which C. gattii might sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d13cc3308d02a52c04e70e009cf9a8a
https://pubmed.ncbi.nlm.nih.gov/26740109
https://pubmed.ncbi.nlm.nih.gov/26740109