Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Shauna M Crowley"'
Autor:
Franziska A Graef, Larissa S Celiberto, Joannie M Allaire, Mimi T Y Kuan, Else S Bosman, Shauna M Crowley, Hyungjun Yang, Justin H Chan, Martin Stahl, Hongbing Yu, Candice Quin, Deanna L Gibson, Elena F Verdu, Kevan Jacobson, Bruce A Vallance
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8, p e1009719 (2021)
Reducing food intake is a common host response to infection, yet it remains unclear whether fasting is detrimental or beneficial to an infected host. Despite the gastrointestinal tract being the primary site of nutrient uptake and a common route for
Externí odkaz:
https://doaj.org/article/0e0ea62074644ca3b0f075eb8663545f
Autor:
Shauna M Crowley, Xiao Han, Joannie M Allaire, Martin Stahl, Isabella Rauch, Leigh A Knodler, Bruce A Vallance
Publikováno v:
PLoS Pathogens, Vol 16, Iss 4, p e1008498 (2020)
We investigated the role of the inflammasome effector caspases-1 and -11 during Salmonella enterica serovar Typhimurium infection of murine intestinal epithelial cells (IECs). Salmonella burdens were significantly greater in the intestines of caspase
Externí odkaz:
https://doaj.org/article/038531766fc4486bbc499e93c5ab38da
Autor:
Brandon Sit, Shauna M Crowley, Kirandeep Bhullar, Christine Chieh-Lin Lai, Calvin Tang, Yogesh Hooda, Charles Calmettes, Husain Khambati, Caixia Ma, John H Brumell, Anthony B Schryvers, Bruce A Vallance, Trevor F Moraes
Publikováno v:
PLoS Pathogens, Vol 11, Iss 8, p e1005107 (2015)
Efficient acquisition of extracellular nutrients is essential for bacterial pathogenesis, however the identities and mechanisms for transport of many of these substrates remain unclear. Here, we investigate the predicted iron-binding transporter AfuA
Externí odkaz:
https://doaj.org/article/8a537c844cf04e78a4e9b514d37279a5
Autor:
Xiao Han, Joannie M. Allaire, Shauna M. Crowley, Jocelyn J. Chan, Kelly Lau, Conghao Zhang, Simon A. Hirota, Kirk Bergstrom, Leigh A. Knodler, Bruce A. Vallance
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
The host restricts Salmonella enterica serovar Typhimurium infection of the gut via inflammasome-dependent sloughing of infected epithelial cells. Here we determined that concurrent caspase 1/11-dependent release of the goblet cell-derived mucin, Muc
Externí odkaz:
https://doaj.org/article/6c6253954466475d80d23564be718074
Autor:
Martin Stahl, Jenna Ries, Jenny Vermeulen, Hong Yang, Ho Pan Sham, Shauna M Crowley, Yuliya Badayeva, Stuart E Turvey, Erin C Gaynor, Xiaoxia Li, Bruce A Vallance
Publikováno v:
PLoS Pathogens, Vol 10, Iss 7, p e1004264 (2014)
Campylobacter jejuni is a major source of foodborne illness in the developed world, and a common cause of clinical gastroenteritis. Exactly how C. jejuni colonizes its host's intestines and causes disease is poorly understood. Although it causes seve
Externí odkaz:
https://doaj.org/article/2ed7abe3073d429899f0a2250446147d
Autor:
Kevin Tsai, Caixia Ma, Xiao Han, Joannie Allaire, Genelle R. Lunken, Shauna M. Crowley, Hongbing Yu, Kevan Jacobson, Lijun Xia, John J. Priatel, Bruce A. Vallance
Publikováno v:
Cellular and molecular gastroenterology and hepatology.
Increased intestinal permeability is seen in a variety of inflammatory conditions such as enteric infections and inflammatory bowel disease. Because barrier function can provide a key biomarker of disease severity, it often is assayed in animal model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9371df0a0df5ad69933a909d29ea6cf3
https://pubmed.ncbi.nlm.nih.gov/36244647
https://pubmed.ncbi.nlm.nih.gov/36244647
Autor:
Shauna M. Crowley, Bruce A. Vallance
Publikováno v:
Cell Host & Microbe. 28:771-773
Summary To colonize the nutritionally competitive environment of the gut, invading bacteria must utilize unique metabolites. Two reports in this issue of Cell Host & Microbe describe how Citrobacter rodentium and Escherichia coli leverage colonocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c00f080cac1cc4e2e5fbb24d129fea77
https://doi.org/10.1016/j.chom.2020.11.006
https://doi.org/10.1016/j.chom.2020.11.006
Autor:
Deanna L. Gibson, Joannie M. Allaire, Franziska A. Graef, Hyungjun Yang, Candice Quin, Martin Stahl, Kevan Jacobson, Else S. Bosman, Hongbing Yu, Elena F. Verdu, Justin Y.H. Chan, Mimi T. Y. Kuan, Bruce A. Vallance, Larissa Sbaglia Celiberto, Shauna M. Crowley
Publikováno v:
PLoS Pathogens, Vol 17, Iss 8 (2021)
PLoS Pathogens, Vol 17, Iss 8, p e1009719 (2021)
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 8, p e1009719 (2021)
PLoS Pathogens
Reducing food intake is a common host response to infection, yet it remains unclear whether fasting is detrimental or beneficial to an infected host. Despite the gastrointestinal tract being the primary site of nutrient uptake and a common route for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e657b2233fe138a8ca6b8f68aaf98bb7
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341583/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8341583/?tool=EBI
Autor:
Zohreh Sharafian, Xiaoxia Li, Pascal M. Lavoie, Xiao Han, Anita Poon, Joannie M. Allaire, Shauna M. Crowley, Brian Bressler, Martin Stahl, Bruce A. Vallance, Navjit Moore, Kevan Jacobson
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Intestinal epithelial cells (IEC) reside in close proximity to the gut microbiota and are hypo-responsive to bacterial products, likely to prevent maladaptive inflammatory responses. This is in part due to their strong expression of Single Ig IL-1 re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf7841ec1aee330780fc01d7e25d2bf
https://pubmed.ncbi.nlm.nih.gov/33859245
https://pubmed.ncbi.nlm.nih.gov/33859245
Autor:
Jason G. Smith, Edward Zhao, Bruce A. Vallance, Joannie M. Allaire, Xiao Han, Shauna M. Crowley, Mayumi K. Holly, Leigh A. Knodler
Publikováno v:
Infect Immun
Recent studies have determined that inflammasome signaling plays an important role in driving intestinal epithelial cell (IEC) responses to bacterial infections, such as Salmonella enterica serovar Typhimurium (S. Typhimurium). There are two primary
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cdfeb3547b977568c75c22707445f9e
https://doi.org/10.1128/iai.00017-20
https://doi.org/10.1128/iai.00017-20