Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Shaun Scaramuzza"'
Autor:
Rebecca M. Jones, Joaquin Herrero Ruiz, Shaun Scaramuzza, Sarmi Nath, Chaoyu Liu, Marta Henklewska, Toyoaki Natsume, Robert G. Bristow, Francisco Romero, Masato T. Kanemaki, Agnieszka Gambus
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110260- (2024)
Summary: To ensure timely duplication of the entire eukaryotic genome, thousands of replication machineries (replisomes) act on genomic DNA at any time during S phase. In the final stages of this process, replisomes are unloaded from chromatin. Unloa
Externí odkaz:
https://doaj.org/article/1301c90532be429a8d1333f2902214f5
Autor:
Shaun Scaramuzza, Rebecca M. Jones, Martina Muste Sadurni, Alicja Reynolds-Winczura, Divyasree Poovathumkadavil, Abigail Farrell, Toyoaki Natsume, Patricia Rojas, Cyntia Fernandez Cuesta, Masato T. Kanemaki, Marco Saponaro, Agnieszka Gambus
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
Abstract Cell division is the basis for the propagation of life and requires accurate duplication of all genetic information. DNA damage created during replication (replication stress) is a major cause of cancer, premature aging and a spectrum of oth
Externí odkaz:
https://doaj.org/article/1ddaed01eda54eabb32edba52fee2e2b
Autor:
Rebecca M. Jones, Joaquin Herrero Ruiz, Shaun Scaramuzza, Sarmi Nath, Marta Henklewska, Toyoaki Natsume, Francisco Romero, Masato T. Kanemaki, Agnieszka Gambus
To ensure faultless duplication of the entire genome, eukaryotic replication initiates from thousands of replication origins. Replication forks emanating from origins move through the chromatin until they encounter forks from neighbouring origins, at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::893a3589aad5aad8d1ad84656be02df0
https://doi.org/10.1101/2022.07.12.499744
https://doi.org/10.1101/2022.07.12.499744
Autor:
Shaun Scaramuzza, Martina Muste Sadurni, Divyasree Poovathumkadavil, Toyoaki Natsume, Patricia Rojas, Masato T. Kanemaki, Marco Saponaro, Agnieszka Gambus
Cell division is the basis for the propagation of life and requires accurate duplication of all genetic information. DNA damage created during replication (replication stress) is a major cause of cancer, premature aging and a spectrum of other human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::321e184875841c48508c45d1abe7c6ff
https://doi.org/10.1101/2022.03.23.485338
https://doi.org/10.1101/2022.03.23.485338
Autor:
Divyasree Poovathumkadavil, Rebecca M. Jones, Sara Priego Moreno, Shaun Scaramuzza, Agnieszka Gambus
Publikováno v:
Life Science Alliance
Analysis of the mitotic replisome disassembly pathway in X. laevis egg extract shows that any replisomes retained on chromatin past S-phase are unloaded through formation of K6- and K63-linked ubiquitin chains on Mcm7 by TRAIP ubiquitin ligase and p9