Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Shaun Ruddy"'
Publikováno v:
Cellular Immunology. 201:89-93
Neutrophils express two types of receptor for the Fc region of IgG, FcgammaRII and FcgammaRIIIB. Via these receptors, neutrophils bind IgG complexes that contain more than one IgG molecule. This binding activates functional processes, such as the res
Publikováno v:
Journal of the Neurological Sciences. 165:160-169
We used rat myelinated dorsal root ganglion (MDRG) cultures to study antibody and complement-mediated mechanisms of peripheral demyelinating diseases. Heat inactivated serum from a patient (LT) with peripheral neuropathy and a monoclonal IgM reactive
Publikováno v:
Journal of Immunological Methods. 202:213-216
Thrombospondin (TSP), a platelet glycoprotein, was purified from platelet supernatants applied sequentially to Sepharose 4B and heparin-agarose affinity columns. This TSP inhibited alternative pathway activity in serum as assessed by lysis of rabbit
Publikováno v:
European Journal of Immunology. 25:1481-1484
Activation of the alternative complement pathway of serum produces complexes of properdin (P) and C3 as measured in a double antibody enzyme-linked immunosorbent assay. When purified from serum, these complexes decrease factor B hemolytic activity in
Autor:
Shaun Ruddy, George Moxley
Publikováno v:
Immunology and Allergy Clinics of North America. 14:387-400
Publikováno v:
American journal of kidney diseases : the official journal of the National Kidney Foundation. 25(5)
A 54-year-old man with cryoglobulinemia and chronic hepatitis C infection presented with progressive renal insufficiency caused by membranoproliferative glomerulonephritis. Because of a steady decline in renal function, cyclophosphamide therapy was i
Autor:
Shaun Ruddy
Publikováno v:
Arthritis & Rheumatism. 38:1533-1534
Autor:
Shaun Ruddy, Warren Strober
Publikováno v:
Journal of Allergy and Clinical Immunology. 88:815-816
Publikováno v:
The Journal of Experimental Medicine
The activity of properdin factor D was measured by the generation of the hemolytically active cellular intermediate, EAC43B(D), bearing the C3b-dependent alternate pathway C3 convertase. Treatment of factor D with DFP prevented formation of EAC43B(D)
Autor:
Bruce H. Littman, Shaun Ruddy
Publikováno v:
Cellular Immunology. 43:388-397
Monocyte complement stimulator (MCS), a lymphokine previously shown to increase the rate of synthesis of the second complement component (C2) by human monocytes, is produced by sensitive T lymphocytes when exposed to antigen. MCS production requires