Zobrazeno 1 - 10
of 190
pro vyhledávání: '"Shaun R McColl"'
Autor:
Veronika Bandara, Victoria M Niktaras, Vasiliki J Willett, Hayley Chapman, Noor A Lokman, Anne M Macpherson, Silvana Napoli, Batjargal Gundsambuu, Jade Foeng, Timothy J Sadlon, Justin Coombs, Shaun R McColl, Simon C Barry, Martin K Oehler, Carmela Ricciardelli
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 5, Pp n/a-n/a (2024)
Abstract Objectives Recent studies have identified expression of the non‐functional P2X7 (nfP2X7) receptor on various malignant cells including ovarian cancer, but not on normal cells, which makes it a promising tumour‐associated antigen candidat
Externí odkaz:
https://doaj.org/article/a34eb2d9adae4c50973532aecbe3bf90
Autor:
Newton G Peres, Nancy Wang, Paul Whitney, Sven Engel, Meghanashree M Shreenivas, Ian Comerford, Dianna M Hocking, Anna B Erazo, Irmgard Förster, Andreas Kupz, Thomas Gebhardt, Shaun R McColl, Stephen J McSorley, Sammy Bedoui, Richard A Strugnell
Publikováno v:
PLoS Pathogens, Vol 17, Iss 10, p e1010004 (2021)
While Salmonella enterica is seen as an archetypal facultative intracellular bacterial pathogen where protection is mediated by CD4+ T cells, identifying circulating protective cells has proved very difficult, inhibiting steps to identify key antigen
Externí odkaz:
https://doaj.org/article/3c84a0cce3d2446fb317538977d6aa8e
Autor:
Bart A Eijkelkamp, Jacqueline R Morey, Stephanie L Neville, Aimee Tan, Victoria G Pederick, Nerida Cole, Prashina P Singh, Cheryl-Lynn Y Ong, Raquel Gonzalez de Vega, David Clases, Bliss A Cunningham, Catherine E Hughes, Iain Comerford, Erin B Brazel, Jonathan J Whittall, Charles D Plumptre, Shaun R McColl, James C Paton, Alastair G McEwan, Philip A Doble, Christopher A McDevitt
Publikováno v:
PLoS Pathogens, Vol 15, Iss 8, p e1007957 (2019)
Human zinc deficiency increases susceptibility to bacterial infection. Although zinc supplementation therapies can reduce the impact of disease, the molecular basis for protection remains unclear. Streptococcus pneumoniae is a major cause of bacteria
Externí odkaz:
https://doaj.org/article/c91b75b319b54f9b8df07364e06cec17
Autor:
Ervin E Kara, Iain Comerford, Kevin A Fenix, Cameron R Bastow, Carly E Gregor, Duncan R McKenzie, Shaun R McColl
Publikováno v:
PLoS Pathogens, Vol 10, Iss 2, p e1003905 (2014)
Differentiation of naïve CD4⁺ cells into functionally distinct effector helper T cell subsets, characterised by distinct "cytokine signatures," is a cardinal strategy employed by the mammalian immune system to efficiently deal with the rapidly evo
Externí odkaz:
https://doaj.org/article/87c6e7f644784126b47ab7d93ee7b37e
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45095 (2012)
The class IB phosphoinositide 3-kinase gamma enzyme complex (PI3Kγ) functions in multiple signaling pathways involved in leukocyte activation and migration, making it an attractive target in complex human inflammatory diseases including MS. Here, us
Externí odkaz:
https://doaj.org/article/206fbec605274aec947b8fff2c4c6284
Autor:
Ella S. Green, Lachlan M. Moldenhauer, Holly M. Groome, David J. Sharkey, Peck Y. Chin, Alison S. Care, Rebecca L. Robker, Shaun R. McColl, Sarah A. Robertson
Publikováno v:
JCI Insight.
Autor:
Caitlin A Abbott, Emily L Freimayer, Timona S Tyllis, Todd S Norton, Mohammed Alsharifi, Aaron H S Heng, Stephen M Pederson, Zhipeng Qu, Mark Armstrong, Geoffrey R Hill, Shaun R McColl, Iain Comerford
Type I regulatory (Tr1) cells contribute to immune suppression in the context of chronic infection, autoimmunity, and transplant tolerance. However, their physiological relevance in the resolution of acute respiratory infection is not understood. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5ec3da9206357722320a59534181b5f8
https://doi.org/10.1101/2022.12.06.519368
https://doi.org/10.1101/2022.12.06.519368
Autor:
Cameron R. Bastow, Ervin E. Kara, Timona S. Tyllis, Carola G. Vinuesa, Shaun R. McColl, Iain Comerford
Publikováno v:
Frontiers in Immunology. 13
Follicular T cells including T follicular helper (TFH) and T follicular regulatory (TFR) cells are essential in supporting and regulating the quality of antibody responses that develop in the germinal centre (GC). Follicular T cell migration during t
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Pro-inflammatory CD4+ T helper (Th) cells drive the pathogenesis of many autoimmune conditions. Recent advances have modified views of the phenotype of pro-inflammatory Th cells in autoimmunity, extending the breadth of known Th cell subsets that ope
Autor:
Cameron R, Bastow, Ervin E, Kara, Timona S, Tyllis, Carola G, Vinuesa, Shaun R, McColl, Iain, Comerford
Publikováno v:
Frontiers in immunology. 13
Follicular T cells including T follicular helper (T