Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Shaun R Brinsmade"'
Autor:
Julienne C Kaiser, Alyssa N King, Jason C Grigg, Jessica R Sheldon, David R Edgell, Michael E P Murphy, Shaun R Brinsmade, David E Heinrichs
Publikováno v:
PLoS Genetics, Vol 14, Iss 1, p e1007159 (2018)
Staphylococcus aureus requires branched-chain amino acids (BCAAs; isoleucine, leucine, valine) for protein synthesis, branched-chain fatty acid synthesis, and environmental adaptation by responding to their availability via the global transcriptional
Externí odkaz:
https://doaj.org/article/0379a43205b24fb3b33be7c2044d0e2a
Publikováno v:
PLoS Genetics, Vol 11, Iss 10, p e1005600 (2015)
The global transcriptional regulator, CodY, binds strongly to the regulatory region of the braB gene, which encodes a Bacillus subtilis branched-chain amino acid (BCAA) permease. However, under conditions that maximize CodY activity, braB expression
Externí odkaz:
https://doaj.org/article/c62cf78b178f48b0a981ff7d5b5e3826
Autor:
Augustus Pendleton, Won-Sik Yeo, Shahad Alqahtani, Dennis A. DiMaggio, Carl J. Stone, Zhaotao Li, Vineet K. Singh, Christopher P. Montgomery, Taeok Bae, Shaun R. Brinsmade
Publikováno v:
mBio, Vol 13, Iss 5 (2022)
ABSTRACT Staphylococcus aureus is a ubiquitous Gram-positive bacterium and an opportunistic human pathogen. S. aureus pathogenesis relies on a complex network of regulatory factors that adjust gene expression. Two important factors in this network ar
Externí odkaz:
https://doaj.org/article/ca8119e7cbe4480488831df51158cfed
Publikováno v:
bioRxiv
The composition of phospholipid membranes is critical to regulating the activity of membrane proteins for cellular functions. Cardiolipin is a unique phospholipid present within the bacterial membrane and mitochondria of eukaryotes and plays a role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c60271a5684346713532be927cb051a6
https://europepmc.org/articles/PMC9915654/
https://europepmc.org/articles/PMC9915654/
Autor:
Tyler K. Nygaard, Jennifer G. Dankoff, Shaun R. Brinsmade, Brock Cone, Madison M. Collins, Tyler J. Evans, Jovanka M. Voyich, Willis Pullman, Owen Burroughs, Ranjan K. Behera, Caralyn E. Flack, Kyler B. Pallister, Fermin E. Guerra
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Staphylococcus aureus (S. aureus) causes a range of diseases ranging from superficial skin and soft-tissue infections to invasive and life-threatening conditions (Klevens et al., 2007; Kobayashi et al., 2015). S. aureus utilizes the Sae sensory syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d321c7aa8d545fce05de6bb04636f53c
https://www.frontiersin.org/article/10.3389/fmicb.2020.00561/full
https://www.frontiersin.org/article/10.3389/fmicb.2020.00561/full
Autor:
Shaun R. Brinsmade, Gyan S. Sahukhal, John W. Fitzgerald, Mohamed Sassi, Mohamed O. Elasri, Noella Germain‐Amiot, Brice Felden, Yoann Augagneur, Alyssa N. King
Publikováno v:
Molecular Microbiology
Molecular Microbiology, Wiley, 2020, 113 (2), pp.309-325. ⟨10.1111/mmi.14418⟩
Molecular Microbiology, 2020, 113 (2), pp.309-325. ⟨10.1111/mmi.14418⟩
Molecular Microbiology, Wiley, 2020, 113 (2), pp.309-325. ⟨10.1111/mmi.14418⟩
Molecular Microbiology, 2020, 113 (2), pp.309-325. ⟨10.1111/mmi.14418⟩
International audience; In Staphylococcus aureus, the transcription factor CodY modulates the expression of hundreds of genes, including most virulence factors, in response to the availability of key nutrients like GTP and branched-chain amino acids.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3600be1ae7b327d202282dc2224d248e
https://hal-univ-rennes1.archives-ouvertes.fr/hal-02397672/document
https://hal-univ-rennes1.archives-ouvertes.fr/hal-02397672/document
Autor:
Madison M, Collins, Ranjan K, Behera, Kyler B, Pallister, Tyler J, Evans, Owen, Burroughs, Caralyn, Flack, Fermin E, Guerra, Willis, Pullman, Brock, Cone, Jennifer G, Dankoff, Tyler K, Nygaard, Shaun R, Brinsmade, Jovanka M, Voyich
Publikováno v:
Frontiers in Microbiology
Staphylococcus aureus (S. aureus) causes a range of diseases ranging from superficial skin and soft-tissue infections to invasive and life-threatening conditions (Klevens et al., 2007; Kobayashi et al., 2015). S. aureus utilizes the Sae sensory syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::82be66af5700355540af8972b03b47f3
https://pubmed.ncbi.nlm.nih.gov/32390958
https://pubmed.ncbi.nlm.nih.gov/32390958
Publikováno v:
Curr Opin Microbiol
Bacterial pathogens need to sense and respond to their environments during infection to align cell metabolism and virulence factor production to survive and battle host defenses. Complex regulatory networks including ligand-binding transcription fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8957dfdb4c69dd9e2693599b82c196eb
https://pubmed.ncbi.nlm.nih.gov/32532689
https://pubmed.ncbi.nlm.nih.gov/32532689
Autor:
Kevin D. Mlynek, Marat R. Sadykov, Luke J. Curran, Logan L. Bulock, Carl J. Stone, Kenneth W. Bayles, Shaun R. Brinsmade
Publikováno v:
J Bacteriol
The global regulator CodY links nutrient availability to the regulation of virulence factor gene expression in Staphylococcus aureus, including many genes whose products affect biofilm formation. Antithetical phenotypes of both biofilm deficiency and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0fcfeb8e58e0120f77a7dd1994a1a5e
https://pubmed.ncbi.nlm.nih.gov/32015143
https://pubmed.ncbi.nlm.nih.gov/32015143
Publikováno v:
J Vis Exp
Bacterial virulence genes are often regulated at the transcriptional level by multiple factors that respond to different environmental signals. Some factors act directly on virulence genes; others control pathogenesis by adjusting the expression of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad4e1063bea7b057f5c0e28bd4ce2761
https://doi.org/10.3791/59055
https://doi.org/10.3791/59055