Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Shaun M. Kirwan"'
Autor:
Shaun M. Kirwan, Herman F. Staats, Ashley E. Sobel, Michael D. Gunn, Soman N. Abraham, William M. Gwinn, Brandi T. Johnson
Publikováno v:
Vaccine. 31:1480-1489
Development of nasal immunization for human use is hindered by the lack of acceptable adjuvants. Although CT is an effective adjuvant, its toxicity will likely prevent its use in nasal vaccines. This study compared non-toxin adjuvants to CT for their
Autor:
Shaun M. Kirwan, Hae Woong Choi, Christopher P. Shelburne, Herman F. Staats, Soman N. Abraham, Gulice Y. C. Leung, David Y.-K. Chen
Publikováno v:
MedChemComm. 4:88-94
The development and use of vaccines and their ability to prevent infection/disease is a shining example of the benefit of biomedical research. Modern vaccines often utilize subunit immunogens that exhibit minimal immunogenicity and require the use of
Autor:
Susan K. Hollingshead, Neil L. Sparks, Catherine R. Doil, Richard S. Dondero, W. Michael Foster, David E. Briles, Herman F. Staats, Sheena H. Wang, Anthony J. Hickey, Leslie S. Casey, Kathleen A. Ashcraft, William M. Gwinn, Tom G. Tlusty, Shaun M. Kirwan
Publikováno v:
Vaccine. 28:6901-6914
IL-1α and IL-1β were evaluated for their ability to provide adjuvant activity for the induction of serum antibody responses when nasally-administered with protein antigens in mice and rabbits. In mice, intranasal (i.n.) immunization with pneumococc
Autor:
Herman F. Staats, Carol C. Whisnant, Partha P. Majumder, Shaun M. Kirwan, James L. Stephenson, Diane K. Wagener
Publikováno v:
Clinical and Vaccine Immunology. 17:412-419
Vi polysaccharide from Salmonella enterica serotype Typhi is used as one of the available vaccines to prevent typhoid fever. Measurement of Vi-specific serum antibodies after vaccination with Vi polysaccharide by enzyme-linked immunosorbent assay (EL
Autor:
Herman F. Staats, Barton F. Haynes, Richard M. Scearce, William M. Gwinn, S. Munir Alam, Shaun M. Kirwan, Julia Xianzhi Zhang
Publikováno v:
Infection and Immunity. 75:5443-5452
Passive transfer of antibody may be useful for preexposure prophylaxis against biological agents used as weapons of terror, such asBacillus anthracis. Studies were performed to evaluate the ability of anthrax antiprotective antigen (anti-PA) and anti
There is a current biodefense interest in protection against anthrax. Here, we developed a new generation of stable and effective anthrax vaccine. We studied the immune response elicited by recombinant protective antigen (rPA) delivered intranasally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f642d0051697d3751cfcbbaaf883a8e2
https://europepmc.org/articles/PMC3725471/
https://europepmc.org/articles/PMC3725471/
Publikováno v:
AIDS research and human retroviruses. 22(6)
Immunization by the nasal route is an established method for the induction of mucosal and systemic humoral and cell-mediated antigen-specific responses. However, the effectiveness of nasal immunization is often hampered by the need for increased dose
Autor:
Sheena H. Wang, Neil L. Sparks, Richard S. Dondero, W. Michael Foster, Susan K. Hollingshead, Anthony J. Hickey, Herman F. Staats, William M. Gwinn, Catherine R. Doil, Shaun M. Kirwan, David E. Briles, Tom G. Tlusty, Leslie S. Casey, Kathleen A. Ashcraft
Publikováno v:
Vaccine. 29:2821
Department of Pathology, Duke University Medical Center, Durham, NC 27710, USA Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7571, USA Department of Medicine, Duke University Medical Center, Durham, N
Autor:
Afton McGowen, Nicole A. Paraggio, Ashley E. Sobel, Shaun M. Kirwan, Chris P. Shelburne, Salvatore V. Pizzo, Soman N. Abraham, Herman F Staats
Publikováno v:
The Journal of Immunology. 178:S32-S32
Recent studies have reported that mast cells play a role in the trafficking of dendritic cells and lymphocytes to lymph nodes draining sites of infection. To test the hypothesis that mast cell activators could be used as vaccine adjuvants, C3H/HeN mi