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pro vyhledávání: '"Shaun M. Hug"'
Publikováno v:
Genome Biology and Evolution
Evolutionary rescue occurs when adaptation restores population growth against a lethal stressor. Here, we studied evolutionary rescue by conducting experiments with Escherichia coli at the lethal temperature of 43.0 °C, to determine the adaptive mut
Autor:
Alejandra Rodríguez-Verdugo, Jagdish Suresh Patel, Brandon S. Gaut, Shaun M. Hug, Andrea González-González
Publikováno v:
Molecular Biology and Evolution
González-González, Andrea; Hug, Shaun M; Rodríguez-Verdugo, Alejandra; Patel, Jagdish Suresh; & Gaut, Brandon S. (2017). Adaptive Mutations in RNA Polymerase and the Transcriptional Terminator Rho Have Similar Effects on Escherichia coli Gene Expression.. Molecular biology and evolution, 34(11), 2839-2855. doi: 10.1093/molbev/msx216. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/40j8s0dm
Molecular Biology and Evolution, 34 (11)
González-González, Andrea; Hug, Shaun M; Rodríguez-Verdugo, Alejandra; Patel, Jagdish Suresh; & Gaut, Brandon S. (2017). Adaptive Mutations in RNA Polymerase and the Transcriptional Terminator Rho Have Similar Effects on Escherichia coli Gene Expression.. Molecular biology and evolution, 34(11), 2839-2855. doi: 10.1093/molbev/msx216. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/40j8s0dm
Molecular Biology and Evolution, 34 (11)
Modifications to transcriptional regulators play a major role in adaptation. Here, we compared the effects of multiple beneficial mutations within and between Escherichia coli rpoB, the gene encoding the RNA polymerase β subunit, and rho, which enco
Autor:
Brandon S. Gaut, Shaun M. Hug
Sometimes populations crash and yet recover before being lost completely. Such recoveries have been observed incidentally in evolution experiments using Escherichia coli, and this phenomenon has been termed the “Lazarus effect.” To investigate ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3151556324705fdfea941aca560a7636
Autor:
Shaun M. Hug, Brandon S. Gaut
Publikováno v:
BMC Evolutionary Biology
BMC evolutionary biology, vol 15, iss 1
Hug, SM; & Gaut, BS. (2015). The phenotypic signature of adaptation to thermal stress in Escherichia coli. BMC EVOLUTIONARY BIOLOGY, 15. doi: 10.1186/s12862-015-0457-3. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7nh3z0g3
BMC evolutionary biology, vol 15, iss 1
Hug, SM; & Gaut, BS. (2015). The phenotypic signature of adaptation to thermal stress in Escherichia coli. BMC EVOLUTIONARY BIOLOGY, 15. doi: 10.1186/s12862-015-0457-3. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7nh3z0g3
Background In the short-term, organisms acclimate to stress through phenotypic plasticity, but in the longer term they adapt to stress genetically. The mutations that accrue during adaptation may contribute to completely novel phenotypes, or they may