Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Shaun M. Goodyear"'
Autor:
Ranish K. Patel, Shahrose Rahman, Issac R. Schwantes, Alexandra Bartlett, Robert Eil, Khashayar Farsad, Kathryn Fowler, Shaun M. Goodyear, Lissi Hansen, Adel Kardosh, Nima Nabavizadeh, Flavio G. Rocha, V. Liana Tsikitis, Melissa H. Wong, Skye C. Mayo
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 16, Iss 6, Pp 881-894 (2023)
Colorectal cancer is the second leading cause of cancer-related deaths in the United States and accounts for an estimated 1 million deaths annually worldwide. The liver is the most common site of metastatic spread from colorectal cancer, significantl
Externí odkaz:
https://doaj.org/article/e0e3224e261747e88bbebb52dbd2408b
Autor:
Zahi I. Mitri, Nour Abuhadra, Shaun M. Goodyear, Evthokia A. Hobbs, Andy Kaempf, Alastair M. Thompson, Stacy L. Moulder
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-5 (2022)
Abstract Identifying triple negative breast cancer (TNBC) patients expected to have poor outcomes provides an opportunity to enhance clinical management. We applied an Evolutionary Action Score to functionally characterize TP53 mutations (EAp53) in 9
Externí odkaz:
https://doaj.org/article/9f43d2c137084c2b949a03adf0c1d3b4
Autor:
Duygu Altinok Dindar, Brie Chun, Amy Palma, John Cheney, Madeline Krieger, Kristin Kasschau, Keaton Stagaman, Zahi I. Mitri, Shaun M. Goodyear, Jackilen Shannon, Lisa Karstens, Thomas Sharpton, Zhenzhen Zhang
Publikováno v:
Nutrients, Vol 15, Iss 21, p 4628 (2023)
Breast cancer (BCa) has many well-known risk factors, including age, genetics, lifestyle, and diet; however, the influence of the gut microbiome on BCa remains an emerging area of investigation. This study explores the connection between the gut micr
Externí odkaz:
https://doaj.org/article/d29d323960f44a70894f7d1ec1711186
Publikováno v:
Stem Cells International, Vol 2016 (2016)
The chemokine (C-X-C) receptor type 4 (CXCR4) is an early marker of primordial germ cells (PGCs) essential for their migration and colonization of the gonads. In spermatogonial stem cells (SSCs), the expression of CXCR4 is promoted by the self-renewa
Externí odkaz:
https://doaj.org/article/2c8d9dd98f7a4f3ca1376586bc876c1f
Autor:
Malinda T West, Shaun M Goodyear, Evthokia A Hobbs, Andy Kaempf, Thomas Kartika, Jessica Ribkoff, Brie Chun, Zahi I Mitri
Publikováno v:
The Oncologist.
BackgroundCyclin-dependent kinase 4/6 inhibitors (CDKi) have changed the landscape for treatment of patients with hormone receptor positive, human epidermal growth factor receptor 2-negative (HR+/HER−) metastatic breast cancer (MBC). However, next-
Publikováno v:
Journal of Gastrointestinal Cancer.
Purpose Non-operative management of patients with locally advanced rectal cancer (LARC) is emerging as a popular approach for patients that have no evidence of disease following neoadjuvant therapy. However, high rates of local recurrence or distant
Publikováno v:
JCO Precision Oncology. :904-909
Autor:
Adam Kittai, Alexey V. Danilov, Bria Thurlow, Stephen E. Spurgeon, Daniel O. Persky, Shaun M. Goodyear, Byung Park, Taylor Hashiguchi, Vi Lam, Scott R Best, Craig Okada
Publikováno v:
Haematologica
Publikováno v:
Seminars in Cutaneous Medicine and Surgery. 38:E49-E56
Advancements in smartphone technologies and the use of specialized health care applications offer an exciting new era to promote melanoma awareness to the public and improve education and prevention strategies. These applications also afford an oppor
Autor:
Zahi I. Mitri, Evthokia A. Hobbs, Shaun M. Goodyear, Jeong Youn Lim, Joanna Pucilowska, Brett Johnson, Allison L. Creason, Courtney Betts, Lisa M. Coussens, Shannon McWeeney, Christopher L. Corless, Joe W. Gray, Gordon B. Mills
Publikováno v:
Cancer Research. 82:2149-2149
Background: Emerging data supports PARPi combinations, including PARPi with immune checkpoint blockade (ICB), as effective therapies in TNBC. The Adaptive Multi-Drug Treatment of Evolving Cancers (AMTEC) trial (NCT03801369) is evaluating the PARPi +