Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Shaun H, Pennington"'
Autor:
Angela Hyder-Wright, Anthony Chirwa, Anthony E. Chirwa, Kondwani Jambo, Ben Morton, Emma Carter, Tinashe Kenny-Nyazika, Dima ElSafadi, Jonathan Gonzalez Sanchez, Gift Chiwala, Giancarlo Biagini, Vincent Yip, Paula Saunderson, Shaun H. Pennington, Christopher Myerscough, Madlen Farrar, Andrea M. Collins, Kelly Convey, Daniela M. Ferreira, Tarsizio Chikaonda, Stephen B. Gordon
Publikováno v:
Wellcome Open Research, Vol 8 (2024)
Tuberculosis (TB) caused 1.5 million deaths in 2020, making it the leading infectious killer after COVID-19. Bacille Calmette-Guerin (BCG) is the only licensed vaccine against TB but has sub-optimal efficacy against pulmonary TB and reduced effective
Externí odkaz:
https://doaj.org/article/98c17705dfc6491aa73d483ec7ff6050
Autor:
Kieran Collings, Cedric Boisdon, Tung-Ting Sham, Kevin Skinley, Hyun-Kyung Oh, Tessa Prince, Adham Ahmed, Shaun H. Pennington, Philip J. Brownridge, Thomas Edwards, Giancarlo A. Biagini, Claire E. Eyers, Amanda Lamb, Peter Myers, Simon Maher
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract The novel coronavirus pandemic (COVID-19) has necessitated a global increase in the use of face masks to limit the airborne spread of the virus. The global demand for personal protective equipment has at times led to shortages of face masks
Externí odkaz:
https://doaj.org/article/409957c3687e47d9895926e953749aae
Autor:
Jordan J. Clark, Rebekah Penrice-Randal, Parul Sharma, Xiaofeng Dong, Shaun H. Pennington, Amy E. Marriott, Stefano Colombo, Andrew Davidson, Maia Kavanagh Williamson, David A. Matthews, Lance Turtle, Tessa Prince, Grant L. Hughes, Edward I. Patterson, Ghada Shawli, Daniele F. Mega, Krishanthi Subramaniam, Jo Sharp, Joseph D. Turner, Giancarlo A. Biagini, Andrew Owen, Anja Kipar, Julian A. Hiscox, James P. Stewart
Publikováno v:
Viruses, Vol 16, Iss 6, p 863 (2024)
COVID-19 is a spectrum of clinical symptoms in humans caused by infection with SARS-CoV-2. The coalescence of SARS-CoV-2 with seasonal respiratory viruses, particularly influenza viruses, is a global health concern. To understand this, transgenic mic
Externí odkaz:
https://doaj.org/article/ce2f20723c1d4989840bfe05c1366c88
Autor:
Celina Jin, Malick M Gibani, Shaun H Pennington, Xinxue Liu, Alison Ardrey, Ghaith Aljayyoussi, Maria Moore, Brian Angus, Christopher M Parry, Giancarlo A Biagini, Nicholas A Feasey, Andrew J Pollard
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 12, p e0007955 (2019)
BackgroundThe treatment of enteric fever is complicated by the emergence of antimicrobial resistant Salmonella Typhi. Azithromycin is commonly used for first-line treatment of uncomplicated enteric fever, but the response to treatment may be sub-opti
Externí odkaz:
https://doaj.org/article/9cb2ce75e9304e149217ca0f47e94cda
Autor:
Esther L. German, Bahij Al-Hakim, Elena Mitsi, Shaun H. Pennington, Jenna F. Gritzfeld, Angie D. Hyder-Wright, Antonia Banyard, Stephen B. Gordon, Andrea M. Collins, Daniela M. Ferreira
Publikováno v:
Pneumonia, Vol 10, Iss 1, Pp 1-7 (2018)
Abstract Background The incidence of community-acquired pneumonia and lower respiratory tract infection rises considerably in later life. Immunoglobulin M (IgM) antibody levels to pneumococcal capsular polysaccharide are known to decrease with age; h
Externí odkaz:
https://doaj.org/article/7e4745a52a2d4a8b986ceb4ebcff2155
Autor:
Samantha Donnellan, Shaun H Pennington, Alessandra Ruggiero, Carmen Martinez-Rodriguez, Marion Pouget, Jordan Thomas, Steve A Ward, Georgios Pollakis, Giancarlo A Biagini, William A Paxton
Mycobacterium tuberculosis and human immunodeficiency virus-1 (HIV-1) syndemic interactions are a major global health concern. Despite the clinical significance of coinfection, our understanding of the cellular pathophysiology and the therapeutic pha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52582433eac0f3039d35d4d1be86167c
https://hdl.handle.net/11562/1085557
https://hdl.handle.net/11562/1085557
Autor:
Rachel L Byrne, Susan Gould, Thomas Edwards, Dominic Wooding, Barry Atkinson, Ginny Moore, Kieran Collings, Cedric Boisdon, Simon Maher, Giancarlo Biagini, Emily R Adams, Tom Fletcher, Shaun H Pennington
We present an optimised method for the recovery of laboratory generated SARS-CoV-2 virus by plaque assay. This method allows easy incorporation into existing standard operating procedures of biological containment level 3 (BCL3) laboratories.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c482b3cf0154abc3c38350a0c352564
https://doi.org/10.1101/2022.10.31.514483
https://doi.org/10.1101/2022.10.31.514483
Autor:
Helen Box, Shaun H Pennington, Edyta Kijak, Lee Tatham, Claire H Caygill, Rose C Lopeman, Laura N Jeffreys, Joanne Herriott, Joanne Sharp, Megan Neary, Anthony Valentijn, Henry Pertinez, Paul Curley, Usman Arshad, Rajith KR Rajoli, Steve Rannard, James P. Stewart, Giancarlo A Biagini, Andrew Owen
Antiviral interventions are urgently required to support vaccination programmes and reduce the global burden of COVID-19. Prior to initiation of large-scale clinical trials, robust preclinical data in support of candidate plausibility are required. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ced3ede5533d4549e2592e3ab29697ed
https://doi.org/10.1101/2022.03.03.482788
https://doi.org/10.1101/2022.03.03.482788
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141361 (2015)
The "weekend effect" describes an increase in adverse outcomes for patients admitted at the weekend. Critical care units have moved to higher intensity working patterns to address this with some improved outcomes. However, support services have persi
Externí odkaz:
https://doaj.org/article/a67080d0eb284a57a22f4d2a6a947fa5
Autor:
Git Chung, Edward I Patterson, Maria Georgiou, Grant L. Hughes, Majlinda Lako, Shaun H. Pennington, Ivo Djidrovski, Lyle Armstrong, Martine J. Smit, Jelle van den Bor, Aitor Casas-Sanchez, Giancarlo A. Biagini, Marina Moya-Molina
Publikováno v:
STEM CELLS
Stem Cells, 39(10), 1310-1321. AlphaMed Press
Stem Cells (Dayton, Ohio)
Djidrovski, I, Georgiou, M, Hughes, G L, Patterson, E I, Casas-Sanchez, A, Pennington, S H, Biagini, G A, Moya-Molina, M, van den Bor, J, Smit, M J, Chung, G, Lako, M & Armstrong, L 2021, ' SARS-CoV-2 infects an upper airway model derived from induced pluripotent stem cells ', Stem Cells, vol. 39, no. 10, pp. 1310-1321 . https://doi.org/10.1002/stem.3422
Stem Cells, 39(10), 1310-1321. AlphaMed Press
Stem Cells (Dayton, Ohio)
Djidrovski, I, Georgiou, M, Hughes, G L, Patterson, E I, Casas-Sanchez, A, Pennington, S H, Biagini, G A, Moya-Molina, M, van den Bor, J, Smit, M J, Chung, G, Lako, M & Armstrong, L 2021, ' SARS-CoV-2 infects an upper airway model derived from induced pluripotent stem cells ', Stem Cells, vol. 39, no. 10, pp. 1310-1321 . https://doi.org/10.1002/stem.3422
As one of the primary points of entry of xenobiotic substances and infectious agents into the body, the lungs are subject to a range of dysfunctions and diseases that together account for a significant number of patient deaths. In view of this, there
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b6561c13f65bbf01facea5c691ff657