Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Shaun E Grosskurth"'
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e2857 (2008)
The mouse Xin repeat-containing proteins (mXinalpha and mXinbeta) localize to the intercalated disc in the heart. mXinalpha is able to bundle actin filaments and to interact with beta-catenin, suggesting a role in linking the actin cytoskeleton to N-
Externí odkaz:
https://doaj.org/article/1e9e483b05ff4feab0ae7e6356f83c46
Autor:
James DeGregori, Paul A. Bunn, Vadym Zaberezhnyy, Zhiyong Zhang, Daniel C. Chan, Aik-Choon Tan, Jihye Kim, Shaun E. Grosskurth, Alwin G. Schuller, Matias Casás-Selves, Barbara A. Helfrich, Hannah A. Scarborough
Supplementary methods and materials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a816f53e90f693a03865be5578dcfc7
https://doi.org/10.1158/1078-0432.22463952
https://doi.org/10.1158/1078-0432.22463952
Autor:
James DeGregori, Paul A. Bunn, Vadym Zaberezhnyy, Zhiyong Zhang, Daniel C. Chan, Aik-Choon Tan, Jihye Kim, Shaun E. Grosskurth, Alwin G. Schuller, Matias Casás-Selves, Barbara A. Helfrich, Hannah A. Scarborough
Supplementary Figures
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d933cadbd3ee8bee5b5dd22436475ad
https://doi.org/10.1158/1078-0432.22463955
https://doi.org/10.1158/1078-0432.22463955
Autor:
Huawei Chen, Corinne Reimer, Stephen E. Fawell, Keith Mikule, Michael Zinda, Edward W. Tate, Paul D. Lyne, Jonathan R. Dry, Deborah Lawson, Michelle L. Lamb, Jeffrey W. Johannes, David A. Scott, Dan Widzowski, Michele Mayo, Ryan T. Howard, Nancy Su, Jiaquan Wu, Farzin Gharahdaghi, Wenxian Wang, Xin Wang, Jingwen Zhang, Philip Petteruti, Tony Cheung, Shaun E. Grosskurth, Zebin Wang
Supplemental Fig S1- S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c14ee784e9ce30d950b54ed3d29144
https://doi.org/10.1158/0008-5472.22418555
https://doi.org/10.1158/0008-5472.22418555
Autor:
Huawei Chen, Corinne Reimer, Stephen E. Fawell, Keith Mikule, Michael Zinda, Edward W. Tate, Paul D. Lyne, Jonathan R. Dry, Deborah Lawson, Michelle L. Lamb, Jeffrey W. Johannes, David A. Scott, Dan Widzowski, Michele Mayo, Ryan T. Howard, Nancy Su, Jiaquan Wu, Farzin Gharahdaghi, Wenxian Wang, Xin Wang, Jingwen Zhang, Philip Petteruti, Tony Cheung, Shaun E. Grosskurth, Zebin Wang
PARP proteins represent a class of post-translational modification enzymes with diverse cellular functions. Targeting PARPs has proven to be efficacious clinically, but exploration of the therapeutic potential of PARP inhibition has been limited to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e72f443eea55562ffa6cc913b43229d
https://doi.org/10.1158/0008-5472.c.6510161.v1
https://doi.org/10.1158/0008-5472.c.6510161.v1
Autor:
James DeGregori, Paul A. Bunn, Vadym Zaberezhnyy, Zhiyong Zhang, Daniel C. Chan, Aik-Choon Tan, Jihye Kim, Shaun E. Grosskurth, Alwin G. Schuller, Matias Casás-Selves, Barbara A. Helfrich, Hannah A. Scarborough
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::766b04993540bfc58cfa7d40a7bf44c8
https://doi.org/10.1158/1078-0432.22463958
https://doi.org/10.1158/1078-0432.22463958
Autor:
Huawei Chen, Corinne Reimer, Stephen E. Fawell, Keith Mikule, Michael Zinda, Edward W. Tate, Paul D. Lyne, Jonathan R. Dry, Deborah Lawson, Michelle L. Lamb, Jeffrey W. Johannes, David A. Scott, Dan Widzowski, Michele Mayo, Ryan T. Howard, Nancy Su, Jiaquan Wu, Farzin Gharahdaghi, Wenxian Wang, Xin Wang, Jingwen Zhang, Philip Petteruti, Tony Cheung, Shaun E. Grosskurth, Zebin Wang
Supplemental materials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c90f8ab65849ea462ef14da7c54638
https://doi.org/10.1158/0008-5472.22418558.v1
https://doi.org/10.1158/0008-5472.22418558.v1
Autor:
James DeGregori, Paul A. Bunn, Vadym Zaberezhnyy, Zhiyong Zhang, Daniel C. Chan, Aik-Choon Tan, Jihye Kim, Shaun E. Grosskurth, Alwin G. Schuller, Matias Casás-Selves, Barbara A. Helfrich, Hannah A. Scarborough
Purpose: The emergence of EGFR inhibitors such as gefitinib, erlotinib, and osimertinib has provided novel treatment opportunities in EGFR-driven non–small cell lung cancer (NSCLC). However, most patients with EGFR-driven cancers treated with these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd71b9676171e97bfea558e9e4cb5bf
https://doi.org/10.1158/1078-0432.c.6525582.v1
https://doi.org/10.1158/1078-0432.c.6525582.v1
Autor:
A. Hughes, Patricia McCoon, Stephen Fawell, Gayathri Bommakanti, Simon T. Barry, Deanna A. Mele, Larissa S. Carnevalli, Christopher Womack, Michael Collins, Nanhua Deng, Lukasz Magiera, Mingchao Xie, J. Carl Barrett, Richard Woessner, Srimathi S. Srinivasan, Deanna L. Russell, Shaun E Grosskurth, Corinne Reimer, Maneesh Singh, Minwei Ye, Theresa Proia, Matthew Griffin, Susan Cantin
Publikováno v:
Clinical Cancer Research. 26:6335-6349
Purpose: Danvatirsen is a therapeutic antisense oligonucleotide (ASO) that selectively targets STAT3 and has shown clinical activity in two phase I clinical studies. We interrogated the clinical mechanism of action using danvatirsen-treated patient s
Autor:
Qi Zhang, Bridget Riley-Gillis, Lina Han, Yannan Jia, Alessia Lodi, Haijiao Zhang, Saravanan Ganesan, Rongqing Pan, Sergej N. Konoplev, Shannon R. Sweeney, Jeremy A. Ryan, Yulia Jitkova, Kenneth Dunner, Shaun E. Grosskurth, Priyanka Vijay, Sujana Ghosh, Charles Lu, Wencai Ma, Stephen Kurtz, Vivian R. Ruvolo, Helen Ma, Connie C. Weng, Cassandra L. Ramage, Natalia Baran, Ce Shi, Tianyu Cai, Richard Eric Davis, Venkata L. Battula, Yingchang Mi, Jing Wang, Courtney D. DiNardo, Michael Andreeff, Jeffery W. Tyner, Aaron Schimmer, Anthony Letai, Rose Ann Padua, Carlos E. Bueso-Ramos, Stefano Tiziani, Joel Leverson, Relja Popovic, Marina Konopleva
Publikováno v:
Signal Transduction and Targeted Therapy. 7