Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Shaul Hestrin"'
Publikováno v:
Cell Reports, Vol 33, Iss 3, Pp 108272- (2020)
Summary: Animal behavior is motivated by internal drives, such as thirst and hunger, generated in hypothalamic neurons that project widely to many brain areas. We find that water-restricted mice maintain stable, high-level contrast sensitivity and br
Externí odkaz:
https://doaj.org/article/797daf00dc29461292d8c3aae55996b1
Publikováno v:
Neuron. 99(6)
The subthreshold mechanisms that underlie neuronal correlations in awake animals are poorly understood. Here, we perform dual whole-cell recordings in the visual cortex (V1) of awake mice to investigate membrane potential (Vm) correlations between up
Publikováno v:
Current biology : CB. 28(1)
Higher and lower cortical areas in the visual hierarchy are reciprocally connected [1]. Although much is known about how feedforward pathways shape receptive field properties of visual neurons, relatively little is known about the role of feedback pa
Autor:
Solange P. Brown, Shaul Hestrin
Publikováno v:
Current Opinion in Neurobiology. 19:415-421
A central tenet of neuroscience is that the precise patterns of connectivity among neurons in a given brain area underlie its function. However, assigning any aspect of perception or behavior to the wiring of local circuits has been challenging. Here
Autor:
Shaul Hestrin, Veronika Zsiros
Publikováno v:
Journal of Neurophysiology. 93:3248-3256
The temporal precision of converting excitatory postsynaptic potentials (EPSPs) into spikes at pyramidal cells is critical for the coding of information in the cortex. Several in vitro studies have shown that voltage-dependent conductances in pyramid
Autor:
Shaul Hestrin, Mario Galarreta
Publikováno v:
Proceedings of the National Academy of Sciences. 99:12438-12443
Networks of γ-aminobutyric acid (GABA)ergic interneurons connected via electrical and chemical synapses are thought to play an important role in detecting and promoting synchronous activity in the cerebral cortex. Although the properties of electric
Publikováno v:
Frontiers in Neural Circuits
Frontiers in Neural Circuits, Vol 8 (2014)
Frontiers in Neural Circuits, Vol 8 (2014)
The ascending cholinergic neuromodulatory system sends projections throughout cortex and has been shown to play an important role in a number of cognitive functions including arousal, working memory, and attention. However, despite a wealth of behavi
Autor:
Shaul Hestrin, Mario Galarreta
Publikováno v:
Science. 292:2295-2299
The temporal pattern and relative timing of action potentials among neocortical neurons may carry important information. However, how cortical circuits detect or generate coherent activity remains unclear. Using paired recordings in rat neocortical s
Autor:
Mario Galarreta, Shaul Hestrin
Publikováno v:
Nature Reviews Neuroscience. 2:425-433
Although gap junctions were first demonstrated in the mammalian brain about 30 years ago, the distribution and role of electrical synapses have remained elusive. A series of recent reports has demonstrated that inhibitory interneurons in the cerebral
Publikováno v:
The Journal of Physiology. 526:109-114
The increased release of oxytocin during lactation has been shown to be dependent upon glutamatergic transmission and is associated with an increased synaptic innervation of the supraoptic nucleus (SON). To determine whether the glutamatergic synapti