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pro vyhledávání: '"Shaughn Bryant"'
Autor:
Audrey E. Lord, Liang Zhang, Jamie E. Erickson, Shaughn Bryant, Christine M. Nelson, Stephanie M. Gaudette, Lucy A. Phillips, Annette J. Schwartz Sterman, Soumya Mitra
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-8 (2022)
Abstract A painful, chronic condition, Rheumatoid Arthritis, is marked by bone erosion and soft tissue swelling at the joint. As treatments are investigated in pre-clinical models, characterizing disease progression is integral to assessing treatment
Externí odkaz:
https://doaj.org/article/3d3de82d1b0e43f0b6d7e296c1c4762a
Autor:
Amanda M Schmidt Paustian, Jesus Paez-Cortez, Shaughn Bryant, Susan Westmoreland, Wendy Waegell, Gillian Kingsbury
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182841 (2017)
Mutations in the Interleukin (IL)-23/IL-23 receptor loci are associated with increased inflammatory bowel disease (IBD) susceptibility, and IL-23 neutralization has shown efficacy in early clinical trials. To better understand how an excess of IL-23
Externí odkaz:
https://doaj.org/article/fd68a1fba62c4d07abb5ab434c7ad926
Autor:
Catherine Tripp, Carolyn A. Cuff, Peter F. Slivka, Shaughn Bryant, Lili Huang, Melanie C. Ruzek, Ting Ting Zhang, Guenter Blaich
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 364:474-484
Despite the efficacy of biologics for treatment of rheumatoid arthritis (RA), many patients show inadequate responses and likely require neutralization of multiple mediators. Neutralization of both interleukin (IL)-1β and IL-17A with monoclonal anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f26c83f9432ac4df1e3ba76093a4cf24
https://doi.org/10.1124/jpet.117.243493
https://doi.org/10.1124/jpet.117.243493
Autor:
Melanie C, Ruzek, Lili, Huang, Ting-Ting, Zhang, Shaughn, Bryant, Peter F, Slivka, Carolyn A, Cuff, Catherine, Tripp, Guenter, Blaich
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 364(3)
Despite the efficacy of biologics for treatment of rheumatoid arthritis (RA), many patients show inadequate responses and likely require neutralization of multiple mediators. Neutralization of both interleukin (IL)-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::340db99d4c35deae4542577a770024ff
https://pubmed.ncbi.nlm.nih.gov/29311111
https://pubmed.ncbi.nlm.nih.gov/29311111
Autor:
Farhan Syed, Shaughn Bryant, Regina Mario, Suzanne Mathieu, Elizabeth O'Connor, Jamie Erickson, Wendy Waegell, Anwar Murtaza, Li Chun Wang, Rajesh Kamath, Jijie Gu, Lisa Olson, Schwartz Annette
Publikováno v:
The Journal of Immunology. 188:56.6-56.6
Rheumatoid Arthritis is characterized by chronic inflammation and synovial hyperplasia which leads to the destruction of cartilage and bone. We have shown earlier (Wu et al, 2007) that blocking IL1α/β provides better efficacy than monotherapy in a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93c8d9f3593b1c59672eb76339318242
https://doi.org/10.4049/jimmunol.188.supp.56.6
https://doi.org/10.4049/jimmunol.188.supp.56.6
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