Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Shau‐Kwaun Chen"'
Publikováno v:
Biochemistry and Biophysics Reports, Vol 28, Iss , Pp 101166- (2021)
Hypercholesterolemia induces intracellular accumulation of cholesterol in macrophages and other immune cells, causing immunological dysfunctions. On cellular levels, cholesterol enrichment might lead to mitochondrial metabolic reprogramming and chang
Externí odkaz:
https://doaj.org/article/3fbc3953698d48b6adbaadf12f476b94
Quantitative and functional interrogation of parent-of-origin allelic expression biases in the brain
Autor:
Julio D Perez, Nimrod D Rubinstein, Daniel E Fernandez, Stephen W Santoro, Leigh A Needleman, Olivia Ho-Shing, John J Choi, Mariela Zirlinger, Shau-Kwaun Chen, Jun S Liu, Catherine Dulac
Publikováno v:
eLife, Vol 4 (2015)
The maternal and paternal genomes play different roles in mammalian brains as a result of genomic imprinting, an epigenetic regulation leading to differential expression of the parental alleles of some genes. Here we investigate genomic imprinting in
Externí odkaz:
https://doaj.org/article/a9b57bdbce1841869bebf9aa693b4b3c
Publikováno v:
Journal of Cellular Biochemistry. 123:275-288
Systemic and intracellular metabolic states are critical factors affecting immune cell functions. The metabolic regulator AMP-activated protein kinase (AMPK) senses AMP levels and mediates cellular responses to energy-restrained conditions. The ubiqu
Publikováno v:
Food Science & Nutrition
Food Science & Nutrition, Vol 9, Iss 6, Pp 3240-3249 (2021)
Food Science & Nutrition, Vol 9, Iss 6, Pp 3240-3249 (2021)
Inositol hexaphosphate (IP6) is a dietary compound commonly obtained from corn, rice, etc. Although we may consume significant amount of IP6 daily, it is unclear whether this diet will impact macrophages’ fate and function. Therefore, we characteri
Publikováno v:
Molecular biology reports. 49(12)
Interferon-gamma (IFN-γ) is an immune-derived cytokines in the innate and adaptive immune responses, and functions as a major pro-inflammatory cytokine. IFNγ has previously been reported involving in the regulation of bone metabolism. However, cont
Autor:
Peng-Yuan Chang, Hung-Kang Wu, Yu-Hsu Chen, Yu-Pao Hsu, Ming-Te Cheng, Ching-Hsiao Yu, Shau-Kwaun Chen
Publikováno v:
Molecular biology reports. 49(5)
Clinical data and phenotypes of several in vivo models demonstrated that interleukin-6 (IL-6) is an essential positive regulator in inflammation-induced bone loss. However, how IL-6 affect bone resorption and the osteoclast differentiation remains in
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 28, Iss, Pp 101166-(2021)
Biochemistry and Biophysics Reports, Vol 28, Iss, Pp 101166-(2021)
Hypercholesterolemia induces intracellular accumulation of cholesterol in macrophages and other immune cells, causing immunological dysfunctions. On cellular levels, cholesterol enrichment might lead to mitochondrial metabolic reprogramming and chang
Publikováno v:
Acupuncture & Electro-Therapeutics Research. 42:217-225
Recent advances in neuroendocrinology and immunology have provided an entry to understand acupuncture. Here, we highlight these progresses and use endometriosis as an example to provide a perspective in how to effectively engage acupuncture into mode
Publikováno v:
The Journal of Immunology. 204:224.46-224.46
Inflammation has been associated with bone diseases such as osteoporosis and osteoarthritis. Bone loss were reported in the patients of several inflammatory diseases, such as rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel dise
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. :PO3-1