Zobrazeno 1 - 10
of 291
pro vyhledávání: '"Shattuck, Mark D."'
Autor:
Sumner, Jacob, Meng, Grace, Brandt, Naomi, Grigas, Alex T., Córdoba, Andrés, Shattuck, Mark D., O'Hern, Corey S.
A goal of computational studies of protein-protein interfaces (PPIs) is to predict the binding site between two monomers that form a heterodimer. The simplest version of this problem is to rigidly re-dock the bound forms of the monomers, which involv
Externí odkaz:
http://arxiv.org/abs/2407.16580
Autor:
Cheng, Yuxuan, Lonial, Benjamin F., Sista, Shivnag, Meer, David J., Hofert, Anisa, Weeks, Eric R., Shattuck, Mark D., O'Hern, Corey S.
Publikováno v:
Soft Matter 20 (2024) 8036
Capillary droplets form due to surface tension when two immiscible fluids are mixed. We describe the motion of gravity-driven capillary droplets flowing through narrow constrictions and obstacle arrays in both simulations and experiments. Our new cap
Externí odkaz:
http://arxiv.org/abs/2406.13776
Proteins fold to a specific functional conformation with a densely packed hydrophobic core that controls their stability. We develop a geometric, yet all-atom model for proteins that explains the universal core packing fraction of $\phi_c=0.55$ found
Externí odkaz:
http://arxiv.org/abs/2405.09646
Autor:
Zheng, Yitong, Wang, Dong, Beeghly, Garrett, Fischbach, Claudia, Shattuck, Mark D., O'Hern, Corey S.
Publikováno v:
APL Bioengineering 8 (2024) 036104
Breast cancer invasion into adipose tissue strongly influences disease progression and metastasis. The degree of cancer cell invasion into adipose tissue depends on numerous biochemical and physical properties of cancer cells, adipocytes, and other k
Externí odkaz:
http://arxiv.org/abs/2403.12293
Autor:
Maisuradze, Luka, King, Megan C., Surovtsev, Ivan V., Mochrie, Simon G. J., Shattuck, Mark D., O'Hern, Corey S.
Publikováno v:
PLoS Computational Biology 20 (2024) e1012221
Chromatin is a polymer complex of DNA and proteins that regulates gene expression. The three-dimensional structure and organization of chromatin controls DNA transcription and replication. High-throughput chromatin conformation capture techniques gen
Externí odkaz:
http://arxiv.org/abs/2312.14342
Publikováno v:
ACS omega 9.9 (2024) 10286-10298
The mechanical properties of Cu-Ti alloys have been characterized extensively through experimental studies. However, a detailed understanding of why the strength of Cu increases after a small fraction of Ti atoms is added to the alloy is still missin
Externí odkaz:
http://arxiv.org/abs/2310.05415
Publikováno v:
Phys. Rev. E 109, 034406 (2024)
Previous studies have shown that the interiors of proteins are densely packed, reaching packing fractions that are as large as those found for static packings of individual amino-acid-shaped particles. How can the interiors of proteins take on such h
Externí odkaz:
http://arxiv.org/abs/2309.09065
Publikováno v:
Phys.Rev.Research. 6 (2024) L012036
During epithelial wound healing, cell morphology near the healed wound and the healing rate vary strongly among different developmental stages even for a single species like \textit{Drosophila}. We develop deformable particle (DP) model simulations t
Externí odkaz:
http://arxiv.org/abs/2305.12020
Autor:
Pashine, Nidhi, Wang, Dong, Zhang, Jerry, Patiballa, Sree Kalyan, Witthaus, Sven, Shattuck, Mark D., O'Hern, Corey S., Kramer-Bottiglio, Rebecca
Publikováno v:
Extreme Mechanics Letters 63, 102055 (2023)
Most granular packings possess shear moduli ($G$) that increase with the applied external pressure, and bulk moduli ($B$) that increase or remain constant with pressure. This paper presents "tessellated" granular metamaterials for which both $G$ and
Externí odkaz:
http://arxiv.org/abs/2303.12070
Autor:
Zhang, Jerry, Wang, Dong, Jin, Weiwei, Xia, Annie, Pashine, Nidhi, Kramer-Bottiglio, Rebecca, Shattuck, Mark D., O'Hern, Corey S.
Publikováno v:
Phys. Rev. E 108, 034901 (2023)
Jammed packings of granular materials display complex mechanical response. For example, the ensemble-averaged shear modulus $\left\langle G \right\rangle$ increases as a power-law in pressure $p$ for static packings of soft spherical particles that c
Externí odkaz:
http://arxiv.org/abs/2303.10300