Zobrazeno 1 - 10
of 4 260
pro vyhledávání: '"Shattock, A."'
Publikováno v:
Emerging Trends in Drugs, Addictions, and Health, Vol 4, Iss , Pp 100117- (2024)
Introduction: Synthetic cannabinoid receptor agonists (SCRAs) are frequently used with other psychoactive substances. We aimed to investigate the poly-pharmacology of SCRA-related deaths and mechanism of SCRA toxicity. Methods: NPSAD analysis - Cases
Externí odkaz:
https://doaj.org/article/19f62f17d1f641688df9436f032859cb
Autor:
Yu Jin Chung, Zoe Hoare, Friedrich Baark, Chak Shun Yu, Jia Guo, William Fuller, Richard Southworth, Doerthe Katschinski, Michael P. Murphy, Thomas R. Eykyn, Michael J. Shattock
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 10, Iss , Pp 100108- (2024)
Externí odkaz:
https://doaj.org/article/ec7d30ade53f4faea7757d290d0164cb
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 10, Iss , Pp 100117- (2024)
Externí odkaz:
https://doaj.org/article/add60a7bd1d2476595351fb895d1b7e9
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Individual-based models of infectious disease dynamics commonly use network structures to represent human interactions. Network structures can vary in complexity, from single-layered with homogeneous mixing to multi-layered with clustering a
Externí odkaz:
https://doaj.org/article/cb4b4a9824f94ed78159c7f7e9126610
Autor:
Yu Jin Chung, Zoe Hoare, Friedrich Baark, Chak Shun Yu, Jia Guo, William Fuller, Richard Southworth, Doerthe M. Katschinski, Michael P. Murphy, Thomas R. Eykyn, Michael J. Shattock
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Elevated intracellular sodium Nai adversely affects mitochondrial metabolism and is a common feature of heart failure. The reversibility of acute Na induced metabolic changes is evaluated in Langendorff perfused rat hearts using the Na/K ATP
Externí odkaz:
https://doaj.org/article/8ac1f41d178b4502b68cf04de0eb6baa
Autor:
Aidan M. Michaels, Anna Zoccarato, Zoe Hoare, George Firth, Yu Jin Chung, Philip W. Kuchel, Ajay M. Shah, Michael J. Shattock, Richard Southworth, Thomas R. Eykyn
Publikováno v:
Cancer & Metabolism, Vol 12, Iss 1, Pp 1-16 (2024)
Abstract Background Glycolytic flux is regulated by the energy demands of the cell. Upregulated glycolysis in cancer cells may therefore result from increased demand for adenosine triphosphate (ATP), however it is unknown what this extra ATP turnover
Externí odkaz:
https://doaj.org/article/61fe531d26c740f2a46c9ccc1181bfa7
Autor:
Rachel D. Barton, John S. Tregoning, Ziyin Wang, Daniel Gonçalves-Carneiro, Radhika Patel, Paul F. McKay, Robin J. Shattock
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 36, Iss 1, Pp 102400- (2025)
Self-amplifying RNA (saRNA) is an extremely promising platform because it can produce more protein for less RNA. We used a sort and sequence approach to identify host cell factors associated with transgene expression from saRNA; the hypothesis was th
Externí odkaz:
https://doaj.org/article/d1b2b2f835494133af392e85d66ba723
Autor:
Barton, Rachel D., Tregoning, John S., Wang, Ziyin, Gonçalves-Carneiro, Daniel, Patel, Radhika, McKay, Paul F., Shattock, Robin J.
Publikováno v:
In Molecular Therapy - Nucleic Acids 11 March 2025 36(1)
Autor:
Anja W. Olsen, Ida Rosenkrands, Christina S. Jacobsen, Hannah M. Cheeseman, Max P. Kristiansen, Jes Dietrich, Robin J. Shattock, Frank Follmann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract The clinical development of an effective Chlamydia vaccine requires in-depth understanding of how well protective pre-clinical immune signatures translate to humans. Here, we report a comparative immunological characterization of CTH522/CAF
Externí odkaz:
https://doaj.org/article/2c0e390bee2742f3b8d0b209bed52afb
Autor:
Barbieri, Beatriz D., Peeler, David J., Samnuan, Karnyart, Day, Suzanne, Hu, Kai, Sallah, Hadijatou J., Tregoning, John S., McKay, Paul F., Shattock, Robin J.
Publikováno v:
In Journal of Controlled Release October 2024 374:280-292