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Akademický článek

Overexpressed nicotinamide N‑methyltransferase in endometrial stromal cells induced by macrophages and estradiol contributes to cell proliferation in endometriosis

Autor: Shuhui Hou, Hui Xu, Shating Lei, Dong Zhao

Publikováno v: Cell Death Discovery, Vol 10, Iss 1, Pp 1-11 (2024)

Abstract Endometriosis, an estrogen-dependent chronic inflammatory condition, afflicts reproductive-aged women. However, the underlying pathological mechanisms remain to be elucidated. Nicotinamide N-methyltransferase (NNMT) is a critical enzyme invo

Externí odkaz: https://doaj.org/article/fb4070e94f5b4e279bdd64f3e3c2172e

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Hypoxia-hindered methylation of PTGIS in endometrial stromal cells accelerates endometriosis progression by inducing CD16− NK-cell differentiation

Autor: Haiyan Peng, Lichun Weng, Shating Lei, Shuhui Hou, Shaoliang Yang, Mingqing Li, Dong Zhao

Publikováno v: Experimental & Molecular Medicine. 54:890-905

Prostacyclin (PGI2) plays key roles in shaping the immune microenvironment and modulating vasodilation, whereas its contribution to endometriosis (EMs) remains largely unclear. Our study suggested that prostacyclin synthase (PTGIS)-dependent PGI2 sig

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::82bad42809e8fd0db79aac0ae0219d73
https://doi.org/10.1038/s12276-022-00793-1

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Downregulating HK2 inhibits proliferation of endometrial stromal cells through a noncanonical pathway involving phosphorylation of signal transducer and activator of transcription 1 in endometriosis

Autor: Shuhui, Hou, Shating, Lei, Haiyan, Peng, Lichun, Weng, Siji, Lv, Mingqing, Li, Dong, Zhao

Publikováno v: Biology of Reproduction. 107:488-499

Background Endometriosis is a benign gynecologic disease that causes chronic pelvic pain, dysmenorrhea and infertility and shares several characteristics with malignant tumors, afflicting women of reproductive age. Hexokinase 2 plays an essential rol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e51e1081d0d9c3e3059ebb968b6019
https://doi.org/10.1093/biolre/ioac081

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Hypoxia-hindered methylation of PTGIS in endometrial stromal cells accelerates endometriosis progression by inducing CD16

Autor: Haiyan, Peng, Lichun, Weng, Shating, Lei, Shuhui, Hou, Shaoliang, Yang, Mingqing, Li, Dong, Zhao

Publikováno v: Experimentalmolecular medicine. 54(7)

Prostacyclin (PGI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2acc25f2054a7dbfaf8bc06f7e3b2689
https://pubmed.ncbi.nlm.nih.gov/35781537

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Systematic oxidative stress is not associated with live birth rate in young non-obese patients with polycystic ovarian syndrome undergoing assisted reproduction cycles: A prospective cohort study

Autor: Xiaoming Teng, Yiping Liu, Ling Hong, Shating Lei, Yuanyuan Wu, Xin Huang, Zhiqin Chen, Miaoxin Chen

Publikováno v: European journal of obstetrics, gynecology, and reproductive biology. 253

Oxidative stress may be associated with polycystic ovary syndrome (PCOS) and poor outcomes after assisted reproduction treatment. It is unclear if systematic oxidative stress is correlated with live birth rate in patients with PCOS after controlled o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b1e259cf94ec0aed9b2f47ea78d1991
https://pubmed.ncbi.nlm.nih.gov/32877771

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Autor: Shating, Lei, Yanling, Cao, Jing, Sun, Mingqing, Li, Dong, Zhao

Publikováno v: American journal of translational research. 10(12)

Hydrogen sulfide (H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e7a63afb4b97c828f635d687b95e42dc
https://pubmed.ncbi.nlm.nih.gov/30662667

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