Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Shathiyah, Kulandavelu"'
Autor:
Marissa J. DeFreitas, Elaine L. Shelton, Augusto F. Schmidt, Sydne Ballengee, Runxia Tian, PingPing Chen, Mayank Sharma, Amanda Levine, Emily Davidovic Katz, Claudia Rojas, Carolyn L. Abitbol, Juanita Hunter, Shathiyah Kulandavelu, Shu Wu, Karen C. Young, Merline Benny
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Premature infants are often exposed to hyperoxia. However, there is limited data regarding the mechanistic underpinnings linking neonatal hyperoxia exposure and its contribution to cardio-renal dysfunction in adults born preterm. Our objecti
Externí odkaz:
https://doaj.org/article/e9a60e9e92eb4d72a57c04ca58addd22
Autor:
Merline Benny, Mayank Sharma, Shathiyah Kulandavelu, PingPing Chen, Runxia Tian, Sydne Ballengee, Jiang Huang, Amanda F. Levine, Matteo Claure, Augusto F. Schmidt, Roberto I. Vazquez-Padron, Claudia O. Rodrigues, Shu Wu, Omaida C. Velazquez, Karen C. Young
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Neonatal hyperoxia induces long-term systemic vascular stiffness and cardiovascular remodeling, but the mechanisms are unclear. Chemokine receptor 7 (CXCR7) represents a key regulator of vascular homeostasis and repair by modulating TGF-β1
Externí odkaz:
https://doaj.org/article/1734e60b83044990a6ea1ecd3cf191fc
Autor:
April W. Tan, Xiaoying Tong, Silvia Alvarez-Cubela, Pingping Chen, Aline Guimarães Santana, Alejo A. Morales, Runxia Tian, Rae Infante, Vanessa Nunes de Paiva, Shathiyah Kulandavelu, Merline Benny, Juan Dominguez-Bendala, Shu Wu, Karen C. Young, Claudia O. Rodrigues, Augusto F. Schmidt
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Background: Intra-amniotic inflammation (IAI) is associated with increased risk of preterm birth and bronchopulmonary dysplasia (BPD), but the mechanisms by which IAI leads to preterm birth and BPD are poorly understood, and there are no effective th
Externí odkaz:
https://doaj.org/article/c3673c1112084506864b0db5ed712490
Autor:
Marissa J. DeFreitas, Chryso P. Katsoufis, Merline Benny, Karen Young, Shathiyah Kulandavelu, Hyunyoung Ahn, Anna Sfakianaki, Carolyn L. Abitbol
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
Oxidative stress occurs when there is an imbalance between reactive oxygen species/reactive nitrogen species and antioxidant systems. The interplay between these complex processes is crucial for normal pregnancy and fetal development; however, when o
Externí odkaz:
https://doaj.org/article/53091de4ea154f38bc55d277094d2d69
S‐Nitrosoglutathione Reductase Deficiency Causes Aberrant Placental S‐Nitrosylation and Preeclampsia
Autor:
Shathiyah Kulandavelu, Raul A. Dulce, Christopher I. Murray, Michael A. Bellio, Julia Fritsch, Rosemeire Kanashiro‐Takeuchi, Himanshu Arora, Ellena Paulino, Daniel Soetkamp, Wayne Balkan, Jenny E. Van Eyk, Joshua M. Hare
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 5 (2022)
Background Preeclampsia, a leading cause of maternal and fetal mortality and morbidity, is characterized by an increase in S‐nitrosylated proteins and reactive oxygen species, suggesting a pathophysiologic role for dysregulation in nitrosylation an
Externí odkaz:
https://doaj.org/article/7c58d4a5e22d48efa2ccc96e5a6e59bc
Autor:
Merline Benny, Diana R. Hernandez, Mayank Sharma, Keyvan Yousefi, Shathiyah Kulandavelu, Sunil Batlahally, Ronald Zambrano, Pingping Chen, Eliana C. Martinez, Augusto F. Schmidt, Lina A. Shehadeh, Roberto I. Vazquez‐Padron, Shu Wu, Omaida C. Velazquez, Karen C. Young
Publikováno v:
Physiological Reports, Vol 8, Iss 1, Pp n/a-n/a (2020)
Abstract Supplemental oxygen (O2) therapy in preterm infants impairs lung development, but the impact of O2 on long‐term systemic vascular structure and function has not been well‐explored. The present study tested the hypothesis that neonatal O2
Externí odkaz:
https://doaj.org/article/bd9fec0483194b249531c4ec54aa9250
Autor:
Andreas Damianos, Shathiyah Kulandavelu, Pingping Chen, Patrick Nwajei, Sunil Batlahally, Mayank Sharma, Silvia Alvarez-Cubela, Juan Dominguez-Bendala, Ronald Zambrano, Jian Huang, Joshua M. Hare, Augusto Schmidt, Shu Wu, Merline Benny, Nelson Claure, Karen Young
Publikováno v:
Journal of Applied Physiology. 133:1031-1041
Adults born preterm have an increased risk of pulmonary vascular disease. Extreme preterm infants often require supplemental oxygen but they also exhibit frequent intermittent hypoxemic episodes (IH). Here, we test the hypothesis that neonatal IH ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::896b7d1bf899f705152aca1755a6fc21
https://doi.org/10.1152/japplphysiol.00708.2021
https://doi.org/10.1152/japplphysiol.00708.2021
Autor:
Raul A Dulce, Rosemeire M Kanashiro-Takeuchi, Lauro M Takeuchi, Alessandro G Salerno, Amarylis C B A Wanschel, Shathiyah Kulandavelu, Wayne Balkan, Marilia S S R Zuttion, Renzhi Cai, Andrew V Schally, Joshua M Hare
Publikováno v:
Cardiovascular Research. 118:3586-3601
Aims To test the hypothesis that the activation of the growth hormone-releasing hormone (GHRH) receptor signalling pathway within the myocardium both prevents and reverses diastolic dysfunction and pathophysiologic features consistent with heart fail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc2a2a98eaa511bd53a75be1724a6b4c
https://doi.org/10.1093/cvr/cvac098
https://doi.org/10.1093/cvr/cvac098
Autor:
John Alden Lee, Manish Kuchakulla, Himanshu Arora, Shathiyah Kulandavelu, Evert Gonzalez, Thomas A. Masterson, Joshua M. Hare, Ursula B. Kaiser, Ranjith Ramasamy
Publikováno v:
Frontiers in Endocrinology, Vol 10 (2019)
Objective: The cause of age-related changes in testosterone remains unclear. We hypothesized that increased nitroso-redox imbalance with aging could affect testosterone production.Materials and Methods: We measured several markers of nitroso-redox im
Externí odkaz:
https://doaj.org/article/e75178f10f1b4d2e9e2185b6b9a5ce34
Autor:
Odayme Quesada, Catherine Vladutiu, Emily Defranco, Margo B. Minissian, Nour Makarem, Shathiyah Kulandavelu, Timothy D. Henry, C. Noel Bairey Merz, Natalie Ann Bello, Gregory Talavera, Susan Cheng
Publikováno v:
Journal of the American College of Cardiology. 81:2309
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7179e00be59df2825738bca4cd682bb
https://doi.org/10.1016/s0735-1097(23)02753-5
https://doi.org/10.1016/s0735-1097(23)02753-5