Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Shashwati Kala"'
Autor:
Ting Zhu, Jinghui Guo, Yong Wu, Ting Lei, Jiejun Zhu, Hui Chen, Shashwati Kala, Kin Fung Wong, Chi Pong Cheung, Xiaohui Huang, Xinyi Zhao, Minyi Yang, Lei Sun
Publikováno v:
iScience, Vol 26, Iss 2, Pp 105993- (2023)
Summary: Microglia are the brain’s resident immune cells, performing surveillance to promote homeostasis and healthy functioning. While microglial chemical signaling is well-studied, mechanical cues regulating their function are less well-understoo
Externí odkaz:
https://doaj.org/article/6f22202804194ca081301aaaa7be0414
Autor:
Jinghui Guo, Yong Wu, Zhiyong Gong, Xixi Chen, Fei Cao, Shashwati Kala, Zhihai Qiu, Xinyi Zhao, Jun‐jiang Chen, Dongming He, Taiheng Chen, Rui Zeng, Jiejun Zhu, Kin Fung Wong, Suresh Murugappan, Ting Zhu, Quanxiang Xian, Xuandi Hou, Ye Chun Ruan, Baojun Li, Yu Chao Li, Yao Zhang, Lei Sun
Publikováno v:
Advanced Science, Vol 9, Iss 12, Pp n/a-n/a (2022)
Abstract Optogenetics has become a widely used technique in neuroscience research, capable of controlling neuronal activity with high spatiotemporal precision and cell‐type specificity. Expressing exogenous opsins in the selected cells can induce n
Externí odkaz:
https://doaj.org/article/5eb36057b9c545edbd72b86bb9c8ebc0
Autor:
Xuandi Hou, Zhihai Qiu, Quanxiang Xian, Shashwati Kala, Jianing Jing, Kin Fung Wong, Jiejun Zhu, Jinghui Guo, Ting Zhu, Minyi Yang, Lei Sun
Publikováno v:
Advanced Science, Vol 8, Iss 21, Pp n/a-n/a (2021)
Abstract Ultrasound is a promising new modality for non‐invasive neuromodulation. Applied transcranially, it can be focused down to the millimeter or centimeter range. The ability to improve the treatment's spatial resolution to a targeted brain re
Externí odkaz:
https://doaj.org/article/853cee1e154f4295873f6d58c62b676d
Autor:
Quanxiang Xian, Zhihai Qiu, Shashwati Kala, Jinghui Guo, Jiejun Zhu, Kin Fung Wong, Sean Shu Yi Guo, Ting Zhu, Xuandi Hou, Lei Sun
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100393- (2021)
Summary: Manipulating specific neural activity by targeted ultrasound intervention is a powerful method to gain causal insight into brain functions and treat brain disorders. The technique of sonogenetics enables controlling of cells that are genetic
Externí odkaz:
https://doaj.org/article/923e389ce4e047a79c6aa6f494fca611
Autor:
Zhihai Qiu, Jinghui Guo, Shashwati Kala, Jiejun Zhu, Quanxiang Xian, Weibao Qiu, Guofeng Li, Ting Zhu, Long Meng, Rui Zhang, Hsiao Chang Chan, Hairong Zheng, Lei Sun
Publikováno v:
iScience, Vol 21, Iss , Pp 448-457 (2019)
Summary: Ultrasound brain stimulation is a promising modality for probing brain function and treating brain disease non-invasively and with high spatiotemporal resolution. However, the mechanism underlying its effects remains unclear. Here, we examin
Externí odkaz:
https://doaj.org/article/a7ef390ef1804d62b80cd8c1fd247ea5
Autor:
Lin Song, Yongmin Huang, Xuandi Hou, Yaoheng Yang, Shashwati Kala, Zhihai Qiu, Rui Zhang, Lei Sun
Publikováno v:
Cellular Physiology and Biochemistry, Vol 49, Iss 5, Pp 1825-1839 (2018)
Background/Aims: Sonodynamic therapy (SDT), based on the synergistic effect of low-intensity ultrasound and sonosensitizer, is a potential approach for non-invasive treatment of cancers. In SDT, mitochondria played a crucial role in cell fate determi
Externí odkaz:
https://doaj.org/article/5c4275b18a7948bc9d15ed23a3d0abae
Autor:
Quanxiang Xian, Zhihai Qiu, Suresh Murugappan, Shashwati Kala, Kin Fung Wong, Danni Li, Guofeng Li, Yizhou Jiang, Yong Wu, Min Su, Xuandi Hou, Jiejun Zhu, Jinghui Guo, Weibao Qiu, Lei Sun
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Noninvasive control of neuronal activity in the deep brain can be illuminating for probing brain function and treating dysfunctions. Here, we present a sonogenetic approach for controlling distinct mouse behavior with circuit specificity and subsecon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa7ab9b3800c27ec0b89cab63767f640
https://doi.org/10.1073/pnas.2220575120
https://doi.org/10.1073/pnas.2220575120
Autor:
Jiejun Zhu, Quanxiang Xian, Xuandi Hou, Kin Fung Wong, Tingting Zhu, Zihao Chen, Dongming He, Shashwati Kala, Suresh Murugappan, Jianing Jing, Yong Wu, Xinyi Zhao, Danni Li, Jinghui Guo, Zhihai Qiu, Lei Sun
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Transcranial low-intensity ultrasound is a promising neuromodulation modality, with the advantages of noninvasiveness, deep penetration, and high spatiotemporal accuracy. However, the underlying biological mechanism of ultrasonic neuromodulation rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3539a548d4a2693a6a2092117b0c4b19
https://doi.org/10.1073/pnas.2300291120
https://doi.org/10.1073/pnas.2300291120
Autor:
Ting Zhu, Jinghui Guo, Yong Wu, Ting Lei, Jiejun Zhu, Hui Chen, Shashwati Kala, Kin Fung Wong, Chi Pong Cheung, Xiaohui Huang, Xinyi Zhao, Minyi Yang, Lei Sun
Microglia are the brain’s resident immune cells, performing surveillance to promote homeostasis and healthy functioning. While chemical signaling in microglia is well-studied, the mechanical cues regulating their function are less well-understood.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dea41c05c82df02749d4bb1385a31834
https://doi.org/10.1101/2022.06.17.496581
https://doi.org/10.1101/2022.06.17.496581
Autor:
Zhihai Qiu, Shashwati Kala, Kin Fung Wong, Guohao Wang, Lin Song, Fei Cao, Lei Sun, Xuandi Hou
Publikováno v:
Acta Biomaterialia. 108:313-325
Tumor hypoxia is believed to be a factor limiting successful outcomes of oxygen-consuming cancer therapy, thereby reducing patient survival. A key strategy to overcome tumor hypoxia is to increase the prevalence of oxygen at the tumor site. Oxygen-co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eac6f328ab33673172953ff478106b24
https://doi.org/10.1016/j.actbio.2020.03.034
https://doi.org/10.1016/j.actbio.2020.03.034