Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Shashwat Deepali, Nagar"'
Autor:
Wilmer A Cárdenas, Andrew B Conley, Shashwat Deepali Nagar, Diana L Núñez-Ríos, I King Jordan, María Claudia Lattig
Publikováno v:
PLoS ONE, Vol 19, Iss 11, p e0313777 (2024)
Autosomal recessive conditions are often associated with homozygous mutations showing common ancestral origins and are frequently linked to consanguinity. However, an increasing number of compound heterozygotes are found in diverse, admixed populatio
Externí odkaz:
https://doaj.org/article/1fdc6053b496486b8e06da9c7c68e542
Autor:
Shashwat Deepali Nagar, Priscilla Pemu, Jun Qian, Eric Boerwinkle, Mine Cicek, Cheryl R. Clark, Elizabeth Cohn, Kelly Gebo, Roxana Loperena, Kelsey Mayo, Stephen Mockrin, Lucila Ohno-Machado, Andrea H. Ramirez, Sheri Schully, Ashley Able, Ashley Green, Stephan Zuchner, SEEC Consortium, I. King Jordan, Robert Meller
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The World Health Organization recently defined hypertension and type 2 diabetes (T2D) as modifiable comorbidities leading to dementia and Alzheimer’s disease. In the United States (US), hypertension and T2D are health disparities, with hig
Externí odkaz:
https://doaj.org/article/b71546708faf44d6b850bdc0578b99da
Publikováno v:
BMC Biology, Vol 18, Iss 1, Pp 1-16 (2020)
Abstract Background Pharmacogenomic (PGx) variants mediate how individuals respond to medication, and response differences among racial/ethnic groups have been attributed to patterns of PGx diversity. We hypothesized that genetic ancestry (GA) would
Externí odkaz:
https://doaj.org/article/59a8dbd987ea4e448fcde1d51466999d
Autor:
Shashwat Deepali Nagar, Andrew B. Conley, Aroon T. Chande, Lavanya Rishishwar, Shivam Sharma, Leonardo Mariño-Ramírez, Gabriela Aguinaga-Romero, Fabricio González-Andrade, I. King Jordan
Publikováno v:
HGG Advances, Vol 2, Iss 4, Pp 100050- (2021)
Summary: We investigated the ancestral origins of four Ecuadorian ethnic groups—Afro-Ecuadorian, Mestizo, Montubio, and the Indigenous Tsáchila—in an effort to gain insight on the relationship between ancestry, culture, and the formation of ethn
Externí odkaz:
https://doaj.org/article/b765fb70cdd04dd6974d3d1053fdca09
Autor:
Shashwat Deepali Nagar, Andrew B. Conley, Shivam Sharma, Lavanya Rishishwar, I. King Jordan, Leonardo Mariño-Ramírez
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
C-reactive protein (CRP) is a routinely measured blood biomarker for inflammation. Elevated levels of circulating CRP are associated with response to infection, risk for a number of complex common diseases, and psychosocial stress. The objective of t
Externí odkaz:
https://doaj.org/article/49502ef044f94001bfa77f70d2b56f26
Autor:
Aroon T. Chande, Shashwat Deepali Nagar, Lavanya Rishishwar, Leonardo Mariño-Ramírez, Miguel A. Medina-Rivas, Augusto E. Valderrama-Aguirre, I. King Jordan, Juan Esteban Gallo
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Currently, the vast majority of genomic research cohorts are made up of participants with European ancestry. Genomic medicine will only reach its full potential when genomic studies become more broadly representative of global populations. We are wor
Externí odkaz:
https://doaj.org/article/f0621fff472e4ac38f38f51dc14958e5
Publikováno v:
EClinicalMedicine, Vol 37, Iss , Pp 100960- (2021)
Background: Type 2 diabetes (T2D) is a complex common disease that disproportionately impacts minority ethnic groups in the United Kingdom (UK). Socioeconomic deprivation (SED) is widely considered as a potential explanation for T2D ethnic disparitie
Externí odkaz:
https://doaj.org/article/fa3d9303ac364f59baeb4a287167393b
Autor:
Shashwat Deepali Nagar, A. Melissa Moreno, Emily T. Norris, Lavanya Rishishwar, Andrew B. Conley, Kelly L. O’Neal, Sara Vélez-Gómez, Camila Montes-Rodríguez, Wendy V. Jaraba-Álvarez, Isaura Torres, Miguel A. Medina-Rivas, Augusto Valderrama-Aguirre, I. King Jordan, Juan Esteban Gallo
Publikováno v:
Frontiers in Genetics, Vol 10 (2019)
While genomic approaches to precision medicine hold great promise, they remain prohibitively expensive for developing countries. The precision public health paradigm, whereby healthcare decisions are made at the level of populations as opposed to ind
Externí odkaz:
https://doaj.org/article/8eb5879c6fdb4b208212cf7d51cc8a8c
Autor:
I. King Jordan, John F. McDonald, Leonardo Mariño-Ramírez, Shashwat Deepali Nagar, Dongjo Ban, Lavanya Rishishwar, Kara Keun Lee
While overall cancer mortality has steadily decreased in recent decades, cancer health disparities among racial and ethnic population groups persist. Here we studied the relationship between cancer survival disparities (CSD), genetic ancestry (GA), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc8a5cb8de9fc5ed0b789ab6d5f8a127
https://doi.org/10.1158/0008-5472.c.6513702.v1
https://doi.org/10.1158/0008-5472.c.6513702.v1
Autor:
I. King Jordan, John F. McDonald, Leonardo Mariño-Ramírez, Shashwat Deepali Nagar, Dongjo Ban, Lavanya Rishishwar, Kara Keun Lee
Supplementary Table from Association of Genetic Ancestry and Molecular Signatures with Cancer Survival Disparities: A Pan-Cancer Analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d23234e6fb9f0f0cfe8fd66e9630802
https://doi.org/10.1158/0008-5472.22430721
https://doi.org/10.1158/0008-5472.22430721