Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Shashidhar Joshi"'
Autor:
George Bardsley, Peter Daley-Yates, Amanda Baines, Rodger Kempsford, Mathew Williams, Tony Mallon, Irene Braithwaite, Kylie Riddell, Shashidhar Joshi, Philippe Bareille, Richard Beasley, James Fingleton, on behalf of the study team
Publikováno v:
Respiratory Research, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Fluticasone furoate/Vilanterol trifenatate (FF/VI) is an inhaled corticosteroid/long-acting beta-agonist combination with a prolonged bronchodilator duration of action. We characterised the time-course of onset and offset of airwa
Externí odkaz:
https://doaj.org/article/0ea8d756e76c4259b19588bbbb114934
Autor:
Trevor Shreeves, Nancy Skoura, Shashidhar Joshi, Ann M. Buchanan, Jafar Sadik Shaik, Linda N. Casillas, Rajendra P. Singh
Publikováno v:
Journal of Acquired Immune Deficiency Syndromes (1999)
Supplemental Digital Content is Available in the Text.
Background: The fixed-dose combination (FDC) tablet formulation of abacavir/dolutegravir/lamivudine is indicated for the treatment of HIV-1 infection in adults and pediatric patients weighin
Background: The fixed-dose combination (FDC) tablet formulation of abacavir/dolutegravir/lamivudine is indicated for the treatment of HIV-1 infection in adults and pediatric patients weighin
Autor:
James Fingleton, Richard Beasley, Amanda Baines, Peter T. Daley-Yates, George Bardsley, Kylie Riddell, Shashidhar Joshi, Philippe Bareille
Publikováno v:
60. Kongress der Deutschen Gesellschaft für Pneumologie und Beatmungsmedizin e. V..
Autor:
Naomi Givens, Kimberly K. Adkison, Caifeng Fu, Herta Crauwels, Kristin Di Lullo, Rashmi Mehta, Simon Vanveggel, Shashidhar Joshi, Allen Wolstenholme, Brian Wynne
Publikováno v:
Antimicrobial Agents and Chemotherapy. 62
A complete 2-drug regimen of dolutegravir at 50 mg and rilpivirine at 25 mg was approved to treat HIV-1 infection in virologically suppressed patients after demonstrating acceptable efficacy and tolerability. This study investigated the bioequivalenc
Autor:
Ethan Hoffmann, Johannes M. Freudenberg, Jonathan Haddad, Stewart W. McCallum, Shashidhar Joshi, Deepa Elizabeth Oommen, Eric W. Jacobson, Bruce E. Sands
Publikováno v:
Inflammatory Bowel Diseases
Article first published online 23 November 2015.
Background: Sirtuins are a class of proteins with important physiologic roles in metabolism and inflammation. Sirtuin (silent mating type information regulation 2 homolog) 1, or SIRT1, activation
Background: Sirtuins are a class of proteins with important physiologic roles in metabolism and inflammation. Sirtuin (silent mating type information regulation 2 homolog) 1, or SIRT1, activation
Publikováno v:
Clinical Pharmacology in Drug Development. 5:131-140
A fixed-dose combination (FDC) may improve patient compliance and clinical outcomes in the management of cardiovascular risk in hypertensive and dyslipidemic patients. The study (NCT02075619) evaluated the bioavailability of 2 prototype FDC tablet fo
Autor:
Bardsley, George, Daley-Yates, Peter, Baines, Amanda, Kempsford, Rodger, Williams, Mathew, Mallon, Tony, Braithwaite, Irene, Riddell, Kylie, Shashidhar Joshi, Bareille, Philippe, Beasley, Richard, Fingleton, James
Supplementary appendix: The anti-inflammatory duration of action of fluticasone furoate/vilanterol trifenitate in asthma. (DOCX 97 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c7d04ce4b5d4884ce6b5b6ef0894daf
Autor:
Shashidhar Joshi, Kylie Riddell, Richard Beasley, George Bardsley, Amanda Baines, Philippe Bareille, James Fingleton, Peter T. Daley-Yates
Publikováno v:
Airway Pharmacology and Treatment.
FF is an inhaled corticosteroid (ICS) with higher glucocorticoid receptor (GR) affinity and greater lung retention compared to other ICS. We investigated whether these attributes confer a prolonged duration of anti-inflammatory action. This was a ran
Publikováno v:
Journal of aerosol medicine and pulmonary drug delivery. 30(5)
The unit dose dry powder inhaler (UD-DPI) is being considered as an alternative inhaler platform that, if developed, has the potential to improve access to inhaled respiratory medicines in developing countries.This study compared the systemic exposur
Publikováno v:
Journal of aerosol medicine and pulmonary drug delivery. 30(3)
To compare the systemic exposure of salbutamol following delivery from the unit dose dry powder inhaler (UD-DPI) system with that from the DiskusThis open-label, two-part, six-way crossover, randomized single-dose study in healthy subjects evaluated