Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Shashi S. Suman"'
Autor:
Kuljit Singh, Vahab Ali, Krishn Pratap Singh, Parool Gupta, Shashi S. Suman, Ayan K. Ghosh, Sanjiva Bimal, Krishna Pandey, Pradeep Das
Publikováno v:
Redox Biology, Vol 12, Iss , Pp 350-366 (2017)
Leishmania donovani is the causative organism of the neglected human disease known as visceral leishmaniasis which is often fatal, if left untreated. The cysteine biosynthesis pathway of Leishmania may serve as a potential drug target because it is d
Externí odkaz:
https://doaj.org/article/41e1c0e7f7b342fa88520072dc84f9a6
Publikováno v:
Journal of Pharmacy and Bioallied Sciences, Vol 15, Iss 6, Pp 1069-1071 (2023)
Introduction: A variation in dental pain following tooth extraction and implant placement has been observed. The present study aimed to compare pain in patients undergoing tooth extraction and implant placement. Materials and Methods: Eighty-four pat
Externí odkaz:
https://doaj.org/article/09b270a6431a457fb5ccc31f13d77720
Autor:
Sanjiva Bimal, P. Das, V. N. R. Das, Krishna Pandey, Ashish Kumar Singh, Vahab Ali, Ajay Amit, Roshan Kamal Topno, Shashi S. Suman, Akhilesh Kumar
Publikováno v:
Cytokine. 145
Dendritic cells (DCs), as antigen-presenting cells, can reportedly be infected with Leishmania parasites and hence provide a better option to trigger T-cell primary immune responses and immunological memory. We consistently primed DCs during culture
Autor:
Manas Ranjan Dikhit, Akhilesh Kumar, Sanjiva Bimal, A.P. Singh, Ajay Amit, Vidyanand Ravi Das, Pradeep Das, Ajit K. Thakur, Vikash Kumar, Ashish Kumar Singh, Shashi S. Suman, Vijayamahantesh
Publikováno v:
Molecular Immunology. 82:104-113
In the present study, the efficacy of Leishmania donovani protein disulfide isomerase (LdPDI) as a DNA vaccine was evaluated in BALB/C mice. Mice immunized with the LdPDI-DNA construct were found to be the most immuno-reactive, as the construct induc
Autor:
Sanjiva Bimal, Kuljit Singh, M.Y. Ansari, Asif Equbal, Bidyut Purkait, Amir Zaidi, Shashi S. Suman, Ganesh Chandra Sahoo, Pradeep Das, Krishn Pratap Singh, Ali
Publikováno v:
Biochimie. 121:312-325
Leishmania is a unicellular protozoan parasite which causes leishmaniasis, a neglected tropical disease. It possess a unique thiol metabolism comprising of several proteins among which, tryparedoxin (cTXN) and tryparedoxin peroxidase (cTXNPx), functi
Autor:
Vahab Ali, Krishna Pandey, Amir Zaidi, S. Bimal, Krishn Pratap Singh, Shashi S. Suman, Asif Equbal, Manas Ranjan Dikhit, Shadab Anwar, Kuljit Singh, Pradeep Das
Publikováno v:
Biochimie. 115:120-135
Leishmania donovani is a unicellular protozoon parasite that causes visceral leishmaniasis (VL), which is a fatal disease if left untreated. Certain Fe-S proteins of the TCA cycle and respiratory chain have been found in the Leishmania parasite but t
Autor:
Sanjiva Bimal, Akhilesh Kumar, Shyam Narayan, Hirendra kumar Chourasia, Vidya Nand Rabi Das, Krishna Pandey, Ashish Kumar Singh, Amir Zaidi, Shashi S. Suman, Vikas kumar, Ajay Amit, Pradeep Das, Shubhankar K. Singh, Vahab Ali, Manas Ranjan Dikhit, Raj Kishor Pandey
Publikováno v:
Molecular immunology. 97
We report here a Leishmania donovani ornithine decarboxylase (Ld-ODC) gene used as a DNA vaccine against visceral leishmaniasis in a murine Balb/c mouse model. This study also evaluated the possible mechanism of action directed by this candidate. We
Autor:
Sanjiva Bimal, Asif Equbal, Krishna Pandey, Vahab Ali, Arti Kumari, Roshan Kamal Topno, Krishn Pratap Singh, Parool Gupta, Pradeep Das, Ajay Amit, Shashi S. Suman, Vidyananda Ravidas
Publikováno v:
Cytokine. 108
Leishmaniasis is a neglected tropical disease caused by the unicellular protozoan parasite of genus Leishmania. Tryparedoxin (TXN) is a low molecular mass dithiol protein belonging to oxidoreductases super-family; which function in concert with trypa
Autor:
Sanjiva Bimal, Krishna Pandey, Krishn Pratap Singh, Ayan Kumar Ghosh, Parool Gupta, Kuljit Singh, Pradeep Das, Vahab Ali, Shashi S. Suman
Publikováno v:
Redox Biology
Redox Biology, Vol 12, Iss, Pp 350-366 (2017)
Redox Biology, Vol 12, Iss, Pp 350-366 (2017)
Leishmania donovani is the causative organism of the neglected human disease known as visceral leishmaniasis which is often fatal, if left untreated. The cysteine biosynthesis pathway of Leishmania may serve as a potential drug target because it is d
Autor:
Bipin K. Singh, S. K. Singh, Anupam Yadav, Vahab Ali, Shyam Narayan, Krishna Pandey, Shashi S. Suman, Ajay Amit, Rajesh Chaudhary, V. N. R. Das, Sanjiva Bimal, Pradeep Das
Publikováno v:
Cellular Immunology. 289:76-85
In Leishmania species, protein disulfide isomerase (PDI) – a redox chaperone is primarily associated with virulence and survival. The precise mechanism, especially in relation to redox changes and its effects on immunological responses in visceral