Zobrazeno 1 - 10
of 454
pro vyhledávání: '"Shashi Bala, Singh"'
Autor:
Poojitha Pinjala, Kamatham Pushpa Tryphena, Renuka Prasad, Dharmendra Kumar Khatri, Woong Sun, Shashi Bala Singh, Dalapathi Gugulothu, Saurabh Srivastava, Lalitkumar Vora
Publikováno v:
Biomaterials Research, Vol 27, Iss 1, Pp 1-18 (2023)
Abstract Since its discovery in 2012, CRISPR Cas9 has been tried as a direct treatment approach to correct the causative gene mutation and establish animal models in neurodegenerative disorders. Since no strategy developed until now could completely
Externí odkaz:
https://doaj.org/article/6eba6d186d634b038018c52daa1aac37
Autor:
Padmashri Naren, Khan Sabiya Samim, Kamatham Pushpa Tryphena, Lalitkumar K. Vora, Saurabh Srivastava, Shashi Bala Singh, Dharmendra Kumar Khatri
Publikováno v:
Translational Neurodegeneration, Vol 12, Iss 1, Pp 1-25 (2023)
Abstract The inter-neuronal communication occurring in extensively branched neuronal cells is achieved primarily through the microtubule (MT)-mediated axonal transport system. This mechanistically regulated system delivers cargos (proteins, mRNAs and
Externí odkaz:
https://doaj.org/article/4abbead1430745f5be3529f7dde7527a
Pests and diseases inflict a devastating impact on the quantity and quality of food production. Pesticides play a vital role in crop protection, although their excessive use poses a potential health hazard and a threat to food security and human and
Autor:
Rachit Jain, Nusrat Begum, Kamatham Pushpa Tryphena, Shashi Bala Singh, Saurabh Srivastava, Sachchida Nand Rai, Emanuel Vamanu, Dharmendra Kumar Khatri
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 159, Iss , Pp 114268- (2023)
Parkinson's disease (PD) is marked by the gradual degeneration of dopaminergic neurons and the intracellular build-up of Lewy bodies rich in α-synuclein protein. This impairs various aspects of the mitochondria including the generation of ROS, bioge
Externí odkaz:
https://doaj.org/article/6fc4bc1b1e484262beeefbcef9271c01
Autor:
Vaskuri G S Satya Sainaga Jyothi, Chanti Katta Babu, Rahul Kumar, Pankaj Kumar Singh, Dharmendra Kumar Khatri, Shashi Bala Singh, Jitender Madan
Publikováno v:
Journal of Pharmacy and Bioallied Sciences, Vol 14, Iss 3, Pp 121-125 (2022)
Mastitis has well-recognized harmful effects on dairy farm profitability. Furthermore, mastitis impairs the milk component synthesizing ability of secretary tissues. Various therapies are available for the treatment of clinical mastitis. Meloxicam ex
Externí odkaz:
https://doaj.org/article/f29cd721e11043168bb7cfe904d237e1
Autor:
Nusrat Begum, Aniket Mandhare, Kamatham Pushpa Tryphena, Saurabh Srivastava, Mohd Farooq Shaikh, Shashi Bala Singh, Dharmendra Kumar Khatri
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Gut-brain axis is a dynamic, complex, and bidirectional communication network between the gut and brain. Changes in the microbiota-gut-brain axis are responsible for developing various metabolic, neurodegenerative, and neuropsychiatric disorders. Acc
Externí odkaz:
https://doaj.org/article/bb3adf210a004a17ad43b12913adeffe
Autor:
Akshaya Iyer, Vaskuri G. S. Sainaga Jyothi, Aashruti Agrawal, Dharmendra Kumar Khatri, Saurabh Srivastava, Shashi Bala Singh, Jitender Madan
Publikováno v:
Journal of Advanced Pharmaceutical Technology & Research, Vol 12, Iss 4, Pp 345-355 (2021)
Skin permeation is an integral part of penetration of topical therapeutics. Zero order in addition to Higuchi permeation kinetic is usually preferred in topical drug delivery cargo. Penetration of therapeutic entities through epidermal barrier is a m
Externí odkaz:
https://doaj.org/article/69a36a08b0d84579ac6dc2dba08136aa
Autor:
Priya Gaur, Supriya Saini, Koushik Ray, Krishna Kishore, Kushubakova Nadira Asanbekovna, Almaz Akunov, Abdirashit Maripov, Yogendra Kumar Sharma, Sanjeev Kumar Sharma, Bhuvnesh Kumar, Shashi Bala Singh, Akpay Sarybaev, Praveen Vats
Publikováno v:
Current Research in Biotechnology, Vol 2, Iss , Pp 120-130 (2020)
Lowland residents acclimatize to reduced oxygen availability at high altitude by certain functional alterations in body which vary according to the different lifestyle, geographical location, ethnicity etc. In our study, two different ethnic lowlande
Externí odkaz:
https://doaj.org/article/bced23cf9b354919ac9bf70f0a6e66f2
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 147, Iss , Pp 112656- (2022)
Mitochondrial uncoupling proteins (UCP) are a part of the large family of mitochondrial solute carriers (SLC25s), concentrated in the inner mitochondrial membrane that carries protons from intermembrane space to the matrix. Further, some UCPs are als
Externí odkaz:
https://doaj.org/article/3feceba5914142399c2bc983a316246c
Autor:
Chayanika Gundu, Vijay Kumar Arruri, Bhoomika Sherkhane, Dharmendra Kumar Khatri, Shashi Bala Singh
Publikováno v:
Current Research in Pharmacology and Drug Discovery, Vol 3, Iss , Pp 100087- (2022)
Neuronal dysfunction and subsequent apoptosis under high glucose conditions during diabetes contribute majorly to the manifestation of diabetic peripheral neuropathy (DPN). PERK (protein kinase RNA (PKR)-like ER kinase) one among the three canonical
Externí odkaz:
https://doaj.org/article/25083657042d4500a2005f08a2f27fe0