Zobrazeno 1 - 10
of 76
pro vyhledávání: '"Shashank M Dravid"'
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0294583 (2023)
In this study, we investigated the role of glutamate delta 1 receptor (GluD1) in oligodendrocyte progenitor cell (OPC)-mediated myelination during basal (development) and pathophysiological (cuprizone-induced demyelination) conditions. Initially, we
Externí odkaz:
https://doaj.org/article/cb622de06a6247eb9493b6ee91d02460
Autor:
Roopali Yadav, Brandon G Hillman, Subhash C Gupta, Pratyush Suryavanshi, Jay M Bhatt, Ratnamala Pavuluri, Dustin J Stairs, Shashank M Dravid
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60785 (2013)
Glutamate delta-1 (GluD1) receptors are expressed throughout the forebrain during development with high levels in the hippocampus during adulthood. We have recently shown that deletion of GluD1 receptor results in aberrant emotional and social behavi
Externí odkaz:
https://doaj.org/article/fa7bf2db766c45bb9bc72fda9a57b7b2
Autor:
Roopali Yadav, Subhash C Gupta, Brandon G Hillman, Jay M Bhatt, Dustin J Stairs, Shashank M Dravid
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e32969 (2012)
The delta family of ionotropic glutamate receptors consists of glutamate δ1 (GluD1) and glutamate δ2 (GluD2) receptors. While the role of GluD2 in the regulation of cerebellar physiology is well understood, the function of GluD1 in the central nerv
Externí odkaz:
https://doaj.org/article/385d68ab20d7433ba7a333db01d48af6
Autor:
Muthukumar Kannan, Seema Singh, Divya T. Chemparathy, Abiola A. Oladapo, Dinesh Y. Gawande, Shashank M. Dravid, Shilpa Buch, Susmita Sil
Publikováno v:
Extracellular Vesicles and Circulating Nucleic Acids. 3:133-49
Aim: Activation of microglial NLRP3 inflammasome is an essential contributor to neuroinflammation underlying HIV-associated neurological disorders (HAND). Under pathological conditions, microglia-derived-EVs (MDEVs) can affect neuronal functions by d
Autor:
Dinesh Y. Gawande, Gajanan P. Shelkar, Kishore Kumar S. Narasimhan, Jinxu Liu, Shashank M. Dravid
Publikováno v:
Neurobiology of Disease. 181:106117
Publikováno v:
International Journal of Neuropsychopharmacology
Background Enhancement of N-methyl-D-aspartate (NMDA) receptor function using glycine-site agonist D-cycloserine is known to facilitate fear extinction, providing a means to augment cognitive behavioral therapy in anxiety disorders. A novel class of
Publikováno v:
ORCID
Cocaine-associated memories induce cravings and interfere with the ability of users to cease cocaine use. Reducing the strength of cue-drug memories by facilitating extinction may have therapeutic value for the treatment of cocaine addiction. Here, w
Autor:
Neil Bannister, R. Rothärmel, Zuner A. Bortolotto, Shashank M. Dravid, Rachael Ingram, Guangyu Fang, Graham L. Collingridge, Kiran Sapkota, A. Volianskis, John Georgiou, Divyan Chopra, Blaise M. Costa, Erica S. Burnell, Mark W. Irvine, David E. Jane, Daniel T. Monaghan, Adina T. Michael-Titus, R. Volianskis
Publikováno v:
Neuropharmacology
Different types of memory are thought to rely on different types of synaptic plasticity, many of which depend on the activation of the N-Methyl-D Aspartate (NMDA) subtype of glutamate receptors. Accordingly, there is considerable interest in the poss
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd9d736cdd516f56b3b2f54ce83ee476
https://hdl.handle.net/10919/111856
https://hdl.handle.net/10919/111856
Autor:
Shashank M. Dravid, Diane Choi, Yoland Smith, Anna D Ayala, Dinesh Y. Gawande, Jinxu Liu, Ratnamala Pavuluri, Gajanan P. Shelkar
Publikováno v:
Mol Neurobiol
Glutamate delta-1 receptor (GluD1) is a member of the ionotropic glutamate receptor family expressed at excitatory synapses and functions as a synaptogenic protein by interacting with presynaptic neurexin. We have previously shown that GluD1 plays a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639b8d6816f5081aa1c3d07cb3fd1632
https://europepmc.org/articles/PMC8500932/
https://europepmc.org/articles/PMC8500932/
Publikováno v:
Mol Pharmacol
The GluN2C subunit of the NMDA receptor is enriched in the neurons in nucleus reticularis of the thalamus (nRT), but its role in regulating their function is not well understood. We found that deletion of GluN2C subunit did not affect spike frequency