Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Sharyne Donfield"'
Autor:
David Bonsall, William F. Gregory, Camilla L.C. Ip, Sharyne Donfield, James Iles, M. Azim Ansari, Paolo Piazza, Amy Trebes, Anthony Brown, John Frater, Oliver G. Pybus, Phillip Goulder, Paul Klenerman, Rory Bowden, Edward D. Gomperts, Eleanor Barnes, Amit Kapoor, Colin P. Sharp, Peter Simmonds
Publikováno v:
Emerging Infectious Diseases, Vol 22, Iss 4, Pp 671-678 (2016)
Next-generation sequencing has critical applications in virus discovery, diagnostics, and environmental surveillance. We used metagenomic sequence libraries for retrospective screening of plasma samples for the recently discovered human hepegivirus 1
Externí odkaz:
https://doaj.org/article/431dd870d60d43119cb10a1b6180f35a
Autor:
Ping An, Sudhir Penugonda, Christian W Thorball, Istvan Bartha, James J Goedert, Sharyne Donfield, Susan Buchbinder, Elizabeth Binns-Roemer, Gregory D Kirk, Wenyan Zhang, Jacques Fellay, Xiao-Fang Yu, Cheryl A Winkler
Publikováno v:
PLoS Genetics, Vol 12, Iss 3, p e1005921 (2016)
Human APOBEC3 cytidine deaminases are intrinsic resistance factors to HIV-1. However, HIV-1 encodes a viral infectivity factor (Vif) that degrades APOBEC3 proteins. In vitro APOBEC3F (A3F) anti-HIV-1 activity is weaker than A3G but is partially resis
Externí odkaz:
https://doaj.org/article/7556ad97625c479d896491e67a54978d
Autor:
Ping An, Rongling Li, Ji Ming Wang, Teizo Yoshimura, Munehisa Takahashi, Ram Samudralal, Stephen J O'Brien, John Phair, James J Goedert, Gregory D Kirk, Jennifer L Troyer, Efe Sezgin, Susan P Buchbinder, Sharyne Donfield, George W Nelson, Cheryl A Winkler
Publikováno v:
PLoS Genetics, Vol 7, Iss 10, p e1002328 (2011)
Chromosome 3p21-22 harbors two clusters of chemokine receptor genes, several of which serve as major or minor coreceptors of HIV-1. Although the genetic association of CCR5 and CCR2 variants with HIV-1 pathogenesis is well known, the role of variatio
Externí odkaz:
https://doaj.org/article/44be1abcb4b44673843136e9a245fd12
Autor:
Ping An, Li Hua Wang, Holli Hutcheson-Dilks, George Nelson, Sharyne Donfield, James J Goedert, Charles R Rinaldo, Susan Buchbinder, Gregory D Kirk, Stephen J O'Brien, Cheryl A Winkler
Publikováno v:
PLoS Pathogens, Vol 3, Iss 6, p e88 (2007)
Human cyclophilin A, or CypA, encoded by the gene peptidyl prolyl isomerase A (PPIA), is incorporated into the HIV type 1 (HIV-1) virion and promotes HIV-1 infectivity by facilitating virus uncoating. We examined the effect of single nucleotide polym
Externí odkaz:
https://doaj.org/article/37e893c7987c43c18aab5f56116df98f
Autor:
Ping An, Priya Duggal, Li Hua Wang, Stephen J O'Brien, Sharyne Donfield, James J Goedert, John Phair, Susan Buchbinder, Gregory D Kirk, Cheryl A Winkler
Publikováno v:
PLoS Genetics, Vol 3, Iss 1, p e19 (2007)
Human apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3 (Apobec3) antiretroviral factors cause hypermutation of proviral DNA leading to degradation or replication-incompetent HIV-1. However, HIV-1 viral infectivity factor (Vif) suppr
Externí odkaz:
https://doaj.org/article/62b9eedc33a84016838139d7c70818bf
Autor:
R. Liesner, Erik Berntorp, Sharyne Donfield, Amy D. Shapiro, Munira Borhany, Stacy E. Croteau, Susan Kearney, Cristina Tarango, Christoph Bidlingmaier, Catherine E. McGuinn, Yasmina L. Abajas, Manuela Carvalho, Roshni Kulkarni, Jan Astermark, Petra LeBeau, Philip Kuriakose, Christine M. Knoll, Stefan Lethagen, Michelle Witkop, Katharina Holstein, Alice J. Cohen, Margaret V. Ragni, Suchitra S. Acharya, Johannes Oldenburg, Eva Funding, Ulrike M. Reiss, Christine L. Kempton, Michael D. Tarantino
Publikováno v:
Haemophilia. 27:49-59
Haemophilia B (HB) is less well studied than haemophilia A (HA); despite similarities between the two inherited bleeding disorders, important differences remain that require further research.B-Natural is a multi-centre, prospective, observational stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e05daff7a3934a8a48410198044c5bcf
https://doi.org/10.1111/hae.14139
https://doi.org/10.1111/hae.14139
Autor:
Salim I. Khakoo, Anatoli Kamali, Susan Allen, Vinodh A. Edward, Becca Asquith, Gregory D. Kirk, Pat Fast, William Kilembe, Lies Boelen, Eric Hunter, Chloe L. Thio, Jill Gilmour, Shabir Lakhi, Bisrat J Debebe, Jacquie Astemborski, Sharyne Donfield, James J. Goedert, Eduard J. Sanders, James Lee, Etienne Karita, Pontiano Kaleebu, Iavi Protocol C Investigators, Omu Anzala, Mubiana Inambao, Jianming Tang, Matthew Price
Publikováno v:
eLife, Vol 9 (2020)
Variation in the risk and severity of many autoimmune diseases, malignancies and infections is strongly associated with polymorphisms at the HLA class I loci. These genetic associations provide a powerful opportunity for understanding the etiology of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::084f8968512b11302ee0945bac7a3495
https://elifesciences.org/articles/54558
https://elifesciences.org/articles/54558
Autor:
Marilyn J. Manco-Johnson, Sharyne Donfield, C. Nakar, Taylor A Blades, Jennifer Maahs, Amy D. Shapiro, Y. Chong, Alice Lail
Publikováno v:
Haemophilia. 21:365-373
Current guidelines recommend delaying the start of immune tolerance induction (ITI) until the inhibitor titre is10 Bethesda units (BU) to improve success. This study was conducted to evaluate ITI outcome relative to time to start ITI from inhibitor d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fe762ddacac44b9819d59fc6542c0a6
https://doi.org/10.1111/hae.12608
https://doi.org/10.1111/hae.12608
Publikováno v:
Haemophilia. 20:519-526
Summary. The high cost of clotting factor concentrate (CFC) used to treat haemophilia and von Willebrand disease (VWD) attracts health plans’ attention for cost management strategies such as disease management programmes (DMPs). In 2004, Indiana’
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db08318ecfab7432a3d0cef5997d1d43
https://doi.org/10.1111/hae.12370
https://doi.org/10.1111/hae.12370
Autor:
Sharyne Donfield, J. Kahle, Diana Stichel, Christoph Königs, Dirk Schwabe, Aleksander Orlowski, Ernest T. Parker, John F. Healey, Jan Astermark, Erik Berntorp, Pete Lollar
Publikováno v:
Haemophilia : the official journal of the World Federation of Hemophilia. 23(2)
Introduction: The development of neutralizing antibodies (inhibitors) against coagulation factor VIII (FVIII) is currently the most serious complication for patients with haemophilia A undergoing FVIII replacement therapy. Several genetic factors hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff3e7acc381c26985b279e5b85afe7e1
https://pubmed.ncbi.nlm.nih.gov/27862687
https://pubmed.ncbi.nlm.nih.gov/27862687