Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Shary Yuting Chen"'
Autor:
Yemin Wang, Valerie Lan Tao, Chae Young Shin, Clara Salamanca, Shary Yuting Chen, Christine Chow, Martin Köbel, Susana Ben-Neriah, David Farnell, Christian Steidl, Jessica N Mcalpine, C Blake Gilks, David G Huntsman
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240412 (2020)
Dedifferentiated endometrial carcinoma (DDEC) is a rare but highly aggressive type of endometrial cancer, in which an undifferentiated carcinoma arises from a low-grade endometrioid endometrial carcinoma. The low-grade component is often eclipsed, li
Externí odkaz:
https://doaj.org/article/8cf61091feda407797908083e604abfa
Autor:
David G. Huntsman, Bernard E. Weissman, Jeffrey M. Trent, Gregg B. Morin, T. Michael Underhill, Ralf Hass, Anthony N. Karnezis, Marcel B. Bally, William P.D. Hendricks, Jessica D. Lang, Krystal A. Orlando, Nancy Dos Santos, Chae Young Shin, Galen Lambert, Shane Colborne, Shary Yuting Chen, Yemin Wang
Fig.S1 shows that SCCOHT cells are sensitive to HDAC inhibition. Fig. S2 shows that SCCOHT cells are sensitive to HDAC inhibition or depletion. Fig.S3 shows that SMARCA4/A2 dual deficiency is not associated with hypersensitivity to HDAC inhibitors in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2396ee9de14b76e5d7859ed9f267bb73
https://doi.org/10.1158/1535-7163.22510063.v1
https://doi.org/10.1158/1535-7163.22510063.v1
Autor:
David G. Huntsman, Bernard E. Weissman, Jeffrey M. Trent, Gregg B. Morin, T. Michael Underhill, Ralf Hass, Anthony N. Karnezis, Marcel B. Bally, William P.D. Hendricks, Jessica D. Lang, Krystal A. Orlando, Nancy Dos Santos, Chae Young Shin, Galen Lambert, Shane Colborne, Shary Yuting Chen, Yemin Wang
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) is a rare but extremely lethal malignancy that mainly impacts young women. SCCOHT is characterized by a diploid genome with loss of SMARCA4 and lack of SMARCA2 expression, two mutually ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37952b52d6236e3e9efd5a279b26f72e
https://doi.org/10.1158/1535-7163.c.6539491
https://doi.org/10.1158/1535-7163.c.6539491
Autor:
David G. Huntsman, Bernard E. Weissman, Jeffrey M. Trent, Gregg B. Morin, T. Michael Underhill, Ralf Hass, Anthony N. Karnezis, Marcel B. Bally, William P.D. Hendricks, Jessica D. Lang, Krystal A. Orlando, Nancy Dos Santos, Chae Young Shin, Galen Lambert, Shane Colborne, Shary Yuting Chen, Yemin Wang
Table S1 shows the cell viability inhibitory rate (%) in SCCOHT cell lines vs other cell lines in the epigenetic drug screen. Table S2 shows the effects of Quisinostat on the proteome of BIN67 cells after treatment for 24 or 72 hours. Table S3 shows
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43304537c45779fc06e18054f0e3bb95
https://doi.org/10.1158/1535-7163.22510060.v1
https://doi.org/10.1158/1535-7163.22510060.v1
Autor:
Anthony N. Karnezis, Shary Yuting Chen, Jeffrey M. Trent, Anne Marie Mes-Masson, Natalia Briones, Pilar Ramos, Christine Chow, Winnie Yang, David G. Huntsman, William P.D. Hendricks, Bernard E. Weissman, Yemin Wang, Tjalling Bosse, C Blake Gilks
Publikováno v:
Gynecol Oncol
Gynecologic Oncology, 160(2), 568-578. ACADEMIC PRESS INC ELSEVIER SCIENCE
Gynecologic oncology, vol 160, iss 2
Gynecologic Oncology, 160(2), 568-578. ACADEMIC PRESS INC ELSEVIER SCIENCE
Gynecologic oncology, vol 160, iss 2
Objective. The development of effective cancer treatments depends on the availability of cell lines that faithfully recapitulate the cancer in question. This study definitively re-assigns the histologic identities of two ovarian cancer cell lines, CO
Autor:
C Blake Gilks, Christian Steidl, David G. Huntsman, David Farnell, Shary Yuting Chen, Clara Salamanca, Chae Young Shin, Martin Köbel, Jessica N. McAlpine, Valerie Lan Tao, Susana Ben-Neriah, Christine Chow, Yemin Wang
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240412 (2020)
PLoS ONE
PLoS ONE
Dedifferentiated endometrial carcinoma (DDEC) is a rare but highly aggressive type of endometrial cancer, in which an undifferentiated carcinoma arises from a low-grade endometrioid endometrial carcinoma. The low-grade component is often eclipsed, li
Autor:
Eunice Li, Bernard E. Weissman, Patrick Pirrotte, Dionzie Ong, Krystal A. Orlando, Yemin Wang, David Humtsman, Shary Yuting Chen, Jennifer X Ji, Elizabeth A. Raupach
Publikováno v:
Cancer Research. 80:1459-1459
Small cell carcinoma of the ovary, hypercalcemic type (SCCOHT) and dedifferentiated carcinoma of the ovary or endometrium are rare but highly aggressive types of gynecologic cancers. We and others have recently demonstrated that genetic inactivation
Autor:
David G. Huntsman, Krystal A. Orlando, Yemin Wang, Jessica D. Lang, Shane Colborne, Gregg B. Morin, Shary Yuting Chen, Anthony N. Karnezis, Jeffrey M. Trent, William P.D. Hendricks, Bernard E. Weissman
Publikováno v:
Cancer Research. 78:3673-3673
Small cell carcinoma of the ovary hypercalcemic type (SCCOHT) is a rare and poorly differentiated cancer that impacts young women with an average 2-year survival of less than 35%. We and others have discovered the inactivating mutations of SMARCA4 as