Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sharsti Sandall"'
Autor:
Sharsti Sandall, Timothy S. Lewis, Robert Lawrence, Rachael Hu, Kelly M. Hensley, Sean Allred, Albina Nesterova, Disha Sahetya, Ivan J. Stone, Steven Jin, Roma Yumul, Nicole M. Okeley, Julia H. Cochran, Liem T. Nguyen, Markus Carlson, Christopher I. Leiske, Thomas A. Pires, Lori Westendorf, Christopher Hale, Robert Thurman, Devra J. Olson, John J. Gosink, Marsha L. Mason, Rebecca Mazahreh
Tables S1-S4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f12f4d6de72d7298f62dd976fda384
https://doi.org/10.1158/1535-7163.22551993
https://doi.org/10.1158/1535-7163.22551993
Autor:
Sharsti Sandall, Timothy S. Lewis, Robert Lawrence, Rachael Hu, Kelly M. Hensley, Sean Allred, Albina Nesterova, Disha Sahetya, Ivan J. Stone, Steven Jin, Roma Yumul, Nicole M. Okeley, Julia H. Cochran, Liem T. Nguyen, Markus Carlson, Christopher I. Leiske, Thomas A. Pires, Lori Westendorf, Christopher Hale, Robert Thurman, Devra J. Olson, John J. Gosink, Marsha L. Mason, Rebecca Mazahreh
Figures S1-S9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95040322453266a34a57f4235635b823
https://doi.org/10.1158/1535-7163.22551999
https://doi.org/10.1158/1535-7163.22551999
Autor:
Sharsti Sandall, Timothy S. Lewis, Robert Lawrence, Rachael Hu, Kelly M. Hensley, Sean Allred, Albina Nesterova, Disha Sahetya, Ivan J. Stone, Steven Jin, Roma Yumul, Nicole M. Okeley, Julia H. Cochran, Liem T. Nguyen, Markus Carlson, Christopher I. Leiske, Thomas A. Pires, Lori Westendorf, Christopher Hale, Robert Thurman, Devra J. Olson, John J. Gosink, Marsha L. Mason, Rebecca Mazahreh
SGN-CD228A is an investigational antibody–drug conjugate (ADC) directed to melanotransferrin (CD228, MELTF, MFI2, p97), a cell-surface protein first identified in melanoma. SGN-CD228A consists of a humanized antibody, hL49, with high specificity an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b77206f339225f16ad5ec99c26106011
https://doi.org/10.1158/1535-7163.c.6534823.v1
https://doi.org/10.1158/1535-7163.c.6534823.v1
Autor:
Sharsti Sandall, Timothy S. Lewis, Robert Lawrence, Rachael Hu, Kelly M. Hensley, Sean Allred, Albina Nesterova, Disha Sahetya, Ivan J. Stone, Steven Jin, Roma Yumul, Nicole M. Okeley, Julia H. Cochran, Liem T. Nguyen, Markus Carlson, Christopher I. Leiske, Thomas A. Pires, Lori Westendorf, Christopher Hale, Robert Thurman, Devra J. Olson, John J. Gosink, Marsha L. Mason, Rebecca Mazahreh
Antibody humanization, binding assays, conjugation, mass spec, additional in vivo details
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62f47ad3855a010481915e8deb0a354a
https://doi.org/10.1158/1535-7163.22495327
https://doi.org/10.1158/1535-7163.22495327
Autor:
Devra Olson, Patrick Younan, Bernard Liu, Gabriele Blahnik-Fagan, John Gosink, Katie Snead, Elena Tenn, Kelly Hensley, Disha Sahetya, Albina Nesterova, Margo Zaval, Anthony Cao, Christine O’Day, Ryan Heiser, Timothy Lewis, Shyra Gardai, Taisuke Nakazawa, Masashi Shimazaki, Christopher Carosino, Sharsti Sandall
Publikováno v:
Regular and Young Investigator Award Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85dd650b9b91a8c2d44f7c0b0c35d32c
https://doi.org/10.1136/jitc-2022-sitc2022.1187
https://doi.org/10.1136/jitc-2022-sitc2022.1187
Autor:
Devra Olson, Yen Lin Chia, Enaharo Iboi, Lauren Farr, Maddy Burcher, Anthony Lee, Kelly Hensley, Sean Allred, Abbie Wong, Masashi Shimazaki, Masamichi Mori, Sharsti Sandall, Christopher Carosino
Publikováno v:
Cancer Research. 83:LB246-LB246
Enfortumab vedotin (EV) is a monomethyl auristatin E (MMAE)-containing antibody-drug conjugate directed to Nectin-4, which is highly expressed in bladder cancers. Preclinically, EV has demonstrated tumor cell killing by direct cytotoxicity and bystan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ecbc389645028849f7d4c6fea700789
https://doi.org/10.1158/1538-7445.am2023-lb246
https://doi.org/10.1158/1538-7445.am2023-lb246
Autor:
Christopher Carosino, Devra Olson, Katie Snead, Anthony Lee, Lauren Farr, Amit Garg, Christine O'Day, Esther Trueblood, Jennifer Wright, Mark Bieda, Charles Caldwell, Kelly Hensley, Sean Allred, Bernard Liu, Masashi Shimazaki, Sharsti Sandall
Publikováno v:
Cancer Research. 82:1140-1140
Enfortumab vedotin (EV) is a monomethyl auristatin E (MMAE) containing antibody-drug conjugate directed to Nectin-4, which is highly expressed in bladder cancers. Preclinically, EV has demonstrated tumor cell-killing by direct cytotoxicity, bystander
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53e0c6bc1ec8b3a440f18b9a038adefc
https://doi.org/10.1158/1538-7445.am2022-1140
https://doi.org/10.1158/1538-7445.am2022-1140
Autor:
Robert Lawrence, Kelly Hensley, Christopher Hale, John Gosink, Sean Allred, David Ortiz, Rachael Hu, Christine O'Day, Phillip M. Garfin, Timothy S. Lewis, Marsha Mason, Sharsti Sandall, Scott Peterson, Rebecca Mazahreh, Abbie Wong
Publikováno v:
Cancer Research. 80:2888-2888
Patient-derived xenograft (PDX) models are widely recognized as a powerful preclinical tool. In contrast to cell line-derived xenograft (CDX) models, patient tumors are excised and implanted directly into mice and as such, retain tumor characteristic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33084f2cd650c356fda33dced9def7a6
https://doi.org/10.1158/1538-7445.am2020-2888
https://doi.org/10.1158/1538-7445.am2020-2888
Autor:
Margaret T. Fuller, Luís Pedro F. Resende, Tony Hunter, Gary R. Hime, Justin C. Voog, John R. Yates, D. Leanne Jones, Mariano A. Loza-Coll, Aaron Aslanian, Sharsti Sandall
Publikováno v:
Cell Reports, Vol 7, Iss 3, Pp 722-734 (2014)
SummaryStem cells reside within specialized microenvironments, or niches, that control many aspects of stem cell behavior. Somatic hub cells in the Drosophila testis regulate the behavior of cyst stem cells (CySCs) and germline stem cells (GSCs) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f11209e6ee75f3c6b34473daaa189d7
https://doi.org/10.1016/j.celrep.2014.04.025
https://doi.org/10.1016/j.celrep.2014.04.025
Autor:
Robert P. Lyon, Marsha Quick, Philip N. Moquist, Andrew B. Waight, Sarah Owen, Tim D. Bovee, Sharsti Sandall, Svetlana O. Doronina, Margo Zaval, Jamie A. Mitchell, Nicole Blesie, Peter D. Senter, Kim K. Emmerton
Publikováno v:
Cancer Research. 78:2803-2803
Auristatins are a class of clinically validated antimitotic agents utilized as payloads in antibody-drug conjugates (ADCs). Auristatins display many of the desirable properties necessary for ADC cytotoxins, such as low nanomolar potency, cell permeab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74dfb56287792bb70b6288ba623865d8
https://doi.org/10.1158/1538-7445.am2018-2803
https://doi.org/10.1158/1538-7445.am2018-2803