Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sharron Glide"'
Autor:
Jitka Malčíková, Martin Brejcha, Michalis Iskas, Sarah Mould, Kristina Stepanovska, Zadie Davis, Chrysoula Belessi, David Oscier, Sharron Glide, Šárka Pospíšilová, Kostas Stamatopoulos, Karla Plevová, Achilles Anagnostopoulos, Panagiotis Baliakas, Florence Nguyen-Khac, Frederic Davi, Anne Gardiner, Anastasia Athanasiadou
Publikováno v:
American Journal of Hematology. 89:249-255
The significance of chromosomal translocations (CTRAs) and karyotype complexity (KC) in chronic lymphocytic leukemia (CLL) remains uncertain. To gain insight into these issues, we evaluated a series of 1001 CLL cases with reliable classic cytogenetic
Autor:
Sharron Glide, Sarah Mould, Jonathan C. Strefford, Tanja Stankovic, Anne Gardiner, Ian Tracy, Hazel M. Robinson, David Oscier, Helen Parker
Publikováno v:
Leukemia Research. 36:307-310
Deletion of ATM detected by fluorescent in situ hybridization (FISH) in chronic lymphocytic leukemia predicts short treatment free survival and poor outcome following alkylator/purine analogue therapy. We describe five cases, with a diminished ATM FI
Autor:
Jenny A. Orchard, Terry J. Hamblin, Sarah Mould, Rachel E. Ibbotson, Zadie Davis, Peter Thomas, R. Chapman, David Oscier, Sharron Glide, Anne Gardiner, Martin Corcoran, J. Adrian Copplestone
Publikováno v:
Blood. 100:1177-1184
This study evaluates the prognostic significance of genetic abnormalities (detected at or shortly after presentation), clinical stage, lymphocyte morphology, CD38 expression, and IGVHgene status in 205 patients with chronic lymphocytic leukemia (B-CL
Autor:
David G, Oscier, Anne C, Gardiner, Sarah J, Mould, Sharron, Glide, Zadie A, Davis, Rachel E, Ibbotson, Martin M, Corcoran, Robert M, Chapman, Peter W, Thomas, J Adrian, Copplestone, Jenny A, Orchard, Terry J, Hamblin
Publikováno v:
Blood. 100(4)
This study evaluates the prognostic significance of genetic abnormalities (detected at or shortly after presentation), clinical stage, lymphocyte morphology, CD38 expression, and IGVH gene status in 205 patients with chronic lymphocytic leukemia (B-C
Autor:
Panagiotis Baliakas, Gabriela Vankova, Karla Plevová, Jitka Malčíková, Kostas Stamatopoulos, Achilles Anagnostopoulos, Sharron Glide, Michalis Iskas, Sarah Mould, Anastasia Athanasiadou, Zadie Davis, David Oscier, Šárka Pospíšilová, Anne Gardiner
Publikováno v:
Blood. 120:3915-3915
Abstract 3915 Although chromosomal translocations (CTRAs) are detected relatively frequently, CLL is conspicuous for the paucity of recurrent CTRAs. The biological and clinical significance of CTRAs in CLL remains uncertain, likely reflecting the und
Autor:
J. Ellis, Anne Gardiner, Estela Matutes, Vasantha Brito-Babapulle, David Oscier, Daniel Catovsky, Sharron Glide, Sarah Mould
Publikováno v:
British journal of haematology. 85(3)
We report the cytogenetic findings on 31 cases of splenic lymphoma with villous lymphocytes (SLVL). TPA stimulated cells from peripheral blood (28 cases), spleen (two cases) and lymph node (one case) with SLVL have been analysed. A clonal chromosome
Autor:
Jonathan C. Strefford, Matthew Jj Rose-Zerilli, Anton Parker, Bryan D. Young, Helen Parker, Zadie Davis, Tracy Chaplin, David Oscier, Sharron Glide, Sarah Mold, Miqdad Rajibali, Anne Gardiner
Publikováno v:
Blood. 116:1696-1696
Abstract 1696 Sequential karyotypic and/or FISH analysis in patients with CLL show evidence of genomic evolution in 10 – 20% of cases. Common secondary abnormalities include loss of the second allele of 13q14, additional trisomies or translocations
Autor:
Parker Anton, Jenny A. Orchard, Anne Gardiner, Rachel E. Ibbotson, Peter Thomas, Giles Best, Sharron Glide, Sarah Mould, Zadie Davis, David Oscier
Publikováno v:
ResearcherID
80% of patients with CLL present with a lymphocytosis detected on a routine blood count. Many studies have identified risk factors for disease progression but there remains uncertainty about the magnitude of risk and which factors are most useful in
Autor:
Anton Parker, Zadie Davis, Jenny A. Orchard, David Oscier, Sharron Glide, Sarah Mould, Anne Gardiner
Publikováno v:
Blood. 104:3254-3254
Splenic marginal zone lymphoma (SMZL) is generally an indolent disorder which has a median survival of 10 – 13 years, but a minority of patients pursue a more aggressive clinical course. A number of adverse prognostic factors including the level of
Autor:
Adrian Wiestner, Louis M. Staudt, Zadie Davis, Anne Gardiner, David Oscier, Peter Thomas, Martin Corcoran, Sharron Glide, Jenny A. Orchard, Sarah Mould
Publikováno v:
Blood. 104:954-954
Patients who present with stage AO CLL and have mutated IgVH genes are generally considered to represent a benign sub-set of CLL with prolonged survival .However, within this subgroup there is considerable heterogeneity with regard to disease progres