Engineering Biocatalysts for the C-H Activation of Fatty Acids by Ancestral Sequence Reconstruction.

Autor: Jones BS; School of Chemistry, The University of Manchester, Manchester Institute of Biotechnology (MIB), 131 Princess Street, Manchester, M1 7DN, UK., Ross CM; School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, Brisbane, 4072, Australia., Foley G; School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, Brisbane, 4072, Australia., Pozhydaieva N; School of Chemistry, The University of Manchester, Manchester Institute of Biotechnology (MIB), 131 Princess Street, Manchester, M1 7DN, UK., Sharratt JW; School of Chemistry, The University of Manchester, Manchester Institute of Biotechnology (MIB), 131 Princess Street, Manchester, M1 7DN, UK., Kress N; School of Chemistry, The University of Manchester, Manchester Institute of Biotechnology (MIB), 131 Princess Street, Manchester, M1 7DN, UK., Seibt LS; School of Chemistry, The University of Manchester, Manchester Institute of Biotechnology (MIB), 131 Princess Street, Manchester, M1 7DN, UK., Thomson RES; School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, Brisbane, 4072, Australia., Gumulya Y; School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, Brisbane, 4072, Australia., Hayes MA; Compound Synthesis and Management, Discovery Sciences, R&D, AstraZeneca, Gothenburg, SE., Gillam EMJ; School of Chemistry and Molecular Biosciences, The University of Queensland, St. Lucia, Brisbane, 4072, Australia., Flitsch SL; School of Chemistry, The University of Manchester, Manchester Institute of Biotechnology (MIB), 131 Princess Street, Manchester, M1 7DN, UK.

Publikováno v: Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2024 Apr 24; Vol. 63 (18), pp. e202314869. Date of Electronic Publication: 2024 Mar 27.