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pro vyhledávání: '"Sharpe, HR"'
Autor:
Sharpe, HR
Viral vectors are a next-generation vaccine platform that elicit a robust response from the humoral and cellular arms of the immune system. The importance of this vaccine platform was demonstrated during this PhD with the emergence of SARS-CoV-2 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1064::847f817c5eb1b0d767bea670df6d9e79
https://ora.ox.ac.uk/objects/uuid:3e23a7db-150a-42b4-b33a-59b0c27ac1c4
https://ora.ox.ac.uk/objects/uuid:3e23a7db-150a-42b4-b33a-59b0c27ac1c4
Autor:
Sharpe, HR, Geer, AM, Taylor, LJ, Gridley, BM, Blundell, TJ, Blake, AJ, Davies, ES, Lewis, W, McMaster, J, Robinson, D, Kays, DL
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-8 (2018)
Sharpe, H R, Geer, A M, Taylor, L J, Gridley, B M, Blundell, T J, Blake, A J, Davies, E S, Lewis, W, Mcmaster, J, Robinson, D & Kays, D L 2018, ' Selective reduction and homologation of carbon monoxide by organometallic iron complexes ', Nature Communications, vol. 9, no. 1, 3757 . https://doi.org/10.1038/s41467-018-06242-w
Sharpe, H R, Geer, A M, Taylor, L J, Gridley, B M, Blundell, T J, Blake, A J, Davies, E S, Lewis, W, Mcmaster, J, Robinson, D & Kays, D L 2018, ' Selective reduction and homologation of carbon monoxide by organometallic iron complexes ', Nature Communications, vol. 9, no. 1, 3757 . https://doi.org/10.1038/s41467-018-06242-w
Carbon monoxide is a key C1 feedstock for the industrial production of hydrocarbons, where it is used to make millions of tonnes of chemicals, fuels, and solvents per annum. Many transition metal complexes can coordinate CO, but the formation of new
Autor:
Bissett C; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK. cameron.bissett@linacre.ox.ac.uk., Belij-Rammerstorfer S; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Ulaszewska M; Pandemic Sciences Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Smith H; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK., Kailath R; Pandemic Sciences Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Morris S; Pandemic Sciences Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Powers C; Pandemic Sciences Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Sebastian S; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Sharpe HR; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Allen ER; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Wang Z; Department of Infectious Disease, Imperial College London, London, UK., Cunliffe RF; Department of Infectious Disease, Imperial College London, London, UK., Sallah HJ; Department of Infectious Disease, Imperial College London, London, UK., Spencer AJ; School of Biomedical Sciences and Pharmacy, University of Newcastle, Newcastle, Australia., Gilbert S; Pandemic Sciences Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Tregoning JS; Department of Infectious Disease, Imperial College London, London, UK., Lambe T; Oxford Vaccine Group, Department of Paediatrics, University of Oxford, Oxford, UK.
Publikováno v:
NPJ vaccines [NPJ Vaccines] 2024 Jun 26; Vol. 9 (1), pp. 118. Date of Electronic Publication: 2024 Jun 26.
Autor:
Sharpe HR; Jenner Institute and., Provine NM; Translational Gastroenterology Unit, Experimental Medicine Division, Nuffield Department of Medicine, University of Oxford, United Kingdom., Bowyer GS; Jenner Institute and., Moreira Folegatti P; Jenner Institute and., Belij-Rammerstorfer S; Jenner Institute and., Flaxman A; Jenner Institute and., Makinson R; Jenner Institute and., Hill AV; Jenner Institute and., Ewer KJ; Jenner Institute and., Pollard AJ; Oxford Vaccine Group, Department of Paediatrics, Medical Sciences Division, University of Oxford and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, United Kingdom., Klenerman P; Translational Gastroenterology Unit, Experimental Medicine Division, Nuffield Department of Medicine, University of Oxford, United Kingdom., Gilbert S; Jenner Institute and., Lambe T; Jenner Institute and.; Oxford Vaccine Group, Department of Paediatrics, Medical Sciences Division, University of Oxford and the National Institute for Health Research (NIHR) Oxford Biomedical Research Centre, Oxford, United Kingdom.; Chinese Academy of Medical Science (CAMS) Oxford Institute (COI), University of Oxford, Oxford, United Kingdom.
Publikováno v:
JCI insight [JCI Insight] 2022 Mar 22; Vol. 7 (6). Date of Electronic Publication: 2022 Mar 22.
Autor:
Youngs J; Institute for Infection & Immunity, St. George's University of London, London, United Kingdom.; Clinical Academic Group in Infection and Immunity, St. George's Hospital NHS Trust, London, United Kingdom., Provine NM; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Lim N; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Sharpe HR; Jenner Institute, University of Oxford, Oxford, United Kingdom., Amini A; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Chen YL; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom., Luo J; Respiratory Medicine Unit, and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, United Kingdom., Edmans MD; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Zacharopoulou P; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Chen W; Respiratory Medicine Unit, and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, United Kingdom., Sampson O; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Paton R; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Hurt WJ; Institute for Infection & Immunity, St. George's University of London, London, United Kingdom.; Clinical Academic Group in Infection and Immunity, St. George's Hospital NHS Trust, London, United Kingdom., Duncan DA; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom.; Diamond Light Source, Harwell Science and Innovation Campus, Didcot, United Kingdom., McNaughton AL; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Miao VN; Institute for Medical Engineering and Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, United States of America., Leaver S; Intensive Care Medicine, St George's University Hospital NHS Foundation Trust, London, United Kingdom., Wyncoll DLA; Intensive Care Medicine, Guy's and St Thomas' Hospital NHS Foundation Trust, London, United Kingdom., Ball J; Intensive Care Medicine, St George's University Hospital NHS Foundation Trust, London, United Kingdom., Hopkins P; Centre for Human & Applied Physiological Sciences, School of Basic & Medical Biosciences, Faculty of Life Sciences, & Medicine, King's College, London, United Kingdom., Skelly DT; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Barnes E; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Jenner Institute, University of Oxford, Oxford, United Kingdom., Dunachie S; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Ogg G; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom., Lambe T; Jenner Institute, University of Oxford, Oxford, United Kingdom., Pavord I; Respiratory Medicine Unit, and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, United Kingdom., Shalek AK; Institute for Medical Engineering and Science, Department of Chemistry, and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, United States of America.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, United States of America., Thompson CP; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Xue L; Respiratory Medicine Unit, and Oxford NIHR Biomedical Research Centre, University of Oxford, Oxford, United Kingdom., Macallan DC; Institute for Infection & Immunity, St. George's University of London, London, United Kingdom.; Clinical Academic Group in Infection and Immunity, St. George's Hospital NHS Trust, London, United Kingdom., Goulder P; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Klenerman P; Peter Medawar Building for Pathogen Research, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom.; Translational Gastroenterology Unit, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Bicanic T; Institute for Infection & Immunity, St. George's University of London, London, United Kingdom.; Clinical Academic Group in Infection and Immunity, St. George's Hospital NHS Trust, London, United Kingdom.
Publikováno v:
PLoS pathogens [PLoS Pathog] 2021 Sep 16; Vol. 17 (9), pp. e1009804. Date of Electronic Publication: 2021 Sep 16 (Print Publication: 2021).
Autor:
Spencer AJ; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, UK. alex.spencer@ndm.ox.ac.uk., McKay PF; Department of Infectious Disease, Imperial College London, London, UK., Belij-Rammerstorfer S; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, UK., Ulaszewska M; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, UK., Bissett CD; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, UK., Hu K; Department of Infectious Disease, Imperial College London, London, UK., Samnuan K; Department of Infectious Disease, Imperial College London, London, UK., Blakney AK; Department of Infectious Disease, Imperial College London, London, UK., Wright D; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, UK., Sharpe HR; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, UK., Gilbride C; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, UK., Truby A; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, UK., Allen ER; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, UK., Gilbert SC; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, UK., Shattock RJ; Department of Infectious Disease, Imperial College London, London, UK., Lambe T; Nuffield Department of Medicine, The Jenner Institute, University of Oxford, Oxford, UK.
Publikováno v:
Nature communications [Nat Commun] 2021 May 17; Vol. 12 (1), pp. 2893. Date of Electronic Publication: 2021 May 17.
Autor:
Seed JA; Department of Chemistry, The University of Manchester, Oxford Road, Manchester, M13 9PL, UK., Sharpe HR; Department of Chemistry, The University of Manchester, Oxford Road, Manchester, M13 9PL, UK., Futcher HJ; Department of Chemistry, The University of Manchester, Oxford Road, Manchester, M13 9PL, UK., Wooles AJ; Department of Chemistry, The University of Manchester, Oxford Road, Manchester, M13 9PL, UK., Liddle ST; Department of Chemistry, The University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
Publikováno v:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2020 Sep 07; Vol. 59 (37), pp. 15870-15874. Date of Electronic Publication: 2020 Jun 30.
The early landscape of coronavirus disease 2019 vaccine development in the UK and rest of the world.
Autor:
Sharpe HR; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Gilbride C; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Allen E; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Belij-Rammerstorfer S; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Bissett C; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Ewer K; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK., Lambe T; The Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Publikováno v:
Immunology [Immunology] 2020 Jul; Vol. 160 (3), pp. 223-232.
Autor:
Sharpe HR; Nuffield Department of Medicine, Jenner Institute, University of Oxford, Oxford, UK., Bowyer G; Nuffield Department of Medicine, Jenner Institute, University of Oxford, Oxford, UK., Brackenridge S; Nuffield Department of Medicine, NDM Research Building, University of Oxford, Oxford, UK., Lambe T; Nuffield Department of Medicine, Jenner Institute, University of Oxford, Oxford, UK.
Publikováno v:
Clinical and experimental immunology [Clin Exp Immunol] 2019 May; Vol. 196 (2), pp. 167-177. Date of Electronic Publication: 2019 Apr 09.
Autor:
Sharpe HR; School of Chemistry, University of Nottingham, University Park, Nottingham, NG7 2RD, UK., Geer AM; School of Chemistry, University of Nottingham, University Park, Nottingham, NG7 2RD, UK., Lewis W; School of Chemistry, University of Nottingham, University Park, Nottingham, NG7 2RD, UK., Blake AJ; School of Chemistry, University of Nottingham, University Park, Nottingham, NG7 2RD, UK., Kays DL; School of Chemistry, University of Nottingham, University Park, Nottingham, NG7 2RD, UK.
Publikováno v:
Angewandte Chemie (International ed. in English) [Angew Chem Int Ed Engl] 2017 Apr 18; Vol. 56 (17), pp. 4845-4848. Date of Electronic Publication: 2017 Mar 24.