Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Sharon Yunger"'
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
A major challenge in developing an effective adoptive cancer immunotherapy is the ex-vivo generation of tumor-reactive cells in sufficient numbers and with enhanced cytotoxic potential. It was recently demonstrated that culturing of activated murine
Externí odkaz:
https://doaj.org/article/96cb62cf91db4e359ddc8317e97d3904
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-9 (2019)
Abstract Background Targeting epitopes derived from neo-antigens (or “neo-epitopes”) represents a promising immunotherapy approach with limited off-target effects. However, most peptides predicted using MHC binding prediction algorithms do not in
Externí odkaz:
https://doaj.org/article/93412e43cde04b1286320e9a879e56ca
Autor:
Sharon Yunger, Assaf Bar El, Li-at Zeltzer, Eddie Fridman, Gil Raviv, Menachem Laufer, Jacob Schachter, Gal Markel, Orit Itzhaki, Michal J Besser
Publikováno v:
OncoImmunology, Vol 8, Iss 12 (2019)
Advanced prostate cancer remains incurable and is the second leading cause of mortality in men. Immunotherapy based on the adoptive transfer of tumor-infiltrating lymphocytes (TIL) has demonstrated promising clinical results in patients with metastat
Externí odkaz:
https://doaj.org/article/307d8f06fe994a62a0389ee50e8bdb01
Autor:
Sivan Seliktar-Ofir, Efrat Merhavi-Shoham, Orit Itzhaki, Sharon Yunger, Gal Markel, Jacob Schachter, Michal J. Besser
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Adoptive cell therapy (ACT) of autologous tumor infiltrating lymphocytes (TIL) is an effective immunotherapy for patients with solid tumors, yielding objective response rates of around 40% in refractory patients with metastatic melanoma. Most clinica
Externí odkaz:
https://doaj.org/article/d7d294fb92b74aa58b01f05c3cb0fbea
Autor:
Pinhas Kafri, Sarah E Hasenson, Itamar Kanter, Jonathan Sheinberger, Noa Kinor, Sharon Yunger, Yaron Shav-Tal
Publikováno v:
eLife, Vol 5 (2016)
Signal propagation from the cell membrane to a promoter can induce gene expression. To examine signal transmission through sub-cellular compartments and its effect on transcription levels in individual cells within a population, we used the Wnt/β-ca
Externí odkaz:
https://doaj.org/article/039e315350a1465d9ab62d2e4fee5667
The major challenge in developing an effective adoptive cancer immunotherapy, is theex-vivogeneration of tumor-reactive cells, in sufficient numbers and with enhanced cytotoxic potential. It was recently demonstrated, that culturing of activated muri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52d448a0a744ea0c2c4f47018d3f7cb5
https://doi.org/10.1101/2022.07.07.499105
https://doi.org/10.1101/2022.07.07.499105
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-9 (2019)
Journal for Immunotherapy of Cancer
Journal for Immunotherapy of Cancer
Targeting epitopes derived from neo-antigens (or “neo-epitopes”) represents a promising immunotherapy approach with limited off-target effects. However, most peptides predicted using MHC binding prediction algorithms do not induce a CD8 + T cell
Autor:
Sergey Viukov, Yishay Pinto, Erez Y. Levanon, Vladislav Krupalnik, Shay Geula, Itay Maza, Sharon Yunger, Rada Massarwa, Dan Dominissini, Moshe Shay Ben-Haim, Vera Hershkovitz, Ninette Amariglio, Noa Novershtern, Diego Jaitin, Nofar Mor, Yoav Rechavi, Nitzan Kol, Elad Chomsky, Mirie Zerbib, Abed AlFatah Mansour, Sharon Moshitch-Moshkovitz, Gideon Rechavi, Eran Eyal, Yoach Rais, Jacob H. Hanna, Noam Stern-Ginossar, Mali Salmon-Divon, Yair S. Manor, Suhair Hanna, Eyal Peer, Ido Amit
Publikováno v:
Science. 347:1002-1006
mRNA modification regulates pluripotency When stem cells progress from an embryonic pluripotent state toward a particular lineage, molecular switches dismantle the transcription factor network that keeps the cell pluripotent. Geula et al. now show th
Autor:
Alon Kalo, Jonathan Sheinberger, Pinhas Kafri, Yaron Shav-Tal, Noa Neufeld, Sharon Yunger, Erez Lavi
Publikováno v:
Histochemistry and Cell Biology
The kinetic aspects of RNA polymerase II as it transcribes mRNA have been revealed over the past decade by use of live-cell imaging and kinetic analyses. It is now possible to visualize polymerase molecules in action, and most importantly to detect a
Publikováno v:
Nature Protocols. 8:393-408
Transcription kinetics of actively transcribing genes in vivo have generally been measured using tandem gene arrays. However, tandem arrays do not reflect the endogenous state of genome organization in which genes appear as single alleles. Here we pr