Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Sharon X. Simonian"'
Publikováno v:
Neuroendocrinology. 76:93-98
Gonadal steroids exert an important regulatory influence upon the biosynthetic and secretory activity of the somatostatin and growth hormone-releasing hormone (GHRH) neurons controlling the release of growth hormone. It is hypothesized that some of t
Publikováno v:
Molecular and Cellular Endocrinology. 185:185-194
Recent advances in the use of gonadotropin-releasing hormone (GnRH) promoter-driven transgenics in the mouse are beginning to open up the once elusive GnRH neuronal phenotype to detailed molecular and cellular investigation. This review highlights pr
Autor:
Allan E. Herbison, Sharon X. Simonian
Publikováno v:
The Journal of Neuroscience. 21:934-943
We have examined here the role of glutamate in regulating the process of tangential neuronal migration during embryogenesis by investigating the roles of AMPA and NMDA receptors in the migration of the gonadotropin-releasing hormone (GnRH) neurons fr
Autor:
Allan E. Herbison, Sharon X. Simonian
Publikováno v:
Neuroendocrinology. 73:149-156
The mechanisms underlying the migration of the gonadotropin-releasing hormone (GnRH) neurons from the nose into the forebrain are not resolved. In an attempt to characterize further the migrating GnRH neurons, we have employed in situ hybridization t
Autor:
Bernhard Lüscher, Werner Sieghart, Sharon X. Simonian, Christian Essrich, Allan E. Herbison, Michael J. Skynner
Publikováno v:
European Journal of Neuroscience. 12:3488-3496
We have employed transgenic mouse models to examine the functional significance of the gamma2 subunit of the GABA(A) (gamma-aminobutyric acid) receptor to the correct development of gonadotropin-releasing hormone (GnRH) neurons in vivo. In the first
Publikováno v:
The Journal of Comparative Neurology. 411:346-358
Gonadal steroids exert a powerful regulatory influence upon the functioning of gonadotropin-releasing hormone (GnRH) neurons despite the apparent absence of gonadal steroid receptors in these cells. By using retrograde-tracing techniques combined wit
Autor:
Colin M. Rantle, Glenda E. Gillies, Hilary E. Murray, Allan E. Herbison, Sharon X. Simonian, Lydia L. DonCarlos
Publikováno v:
Neuroendocrinology. 70:384-391
The biosynthesis and secretion of somatostatin (SRIH) within the hypothalamic periventricular-median eminence (PeN-ME) pathway follows a sexually differentiated developmental pattern beginning in the early neonatal period. It is generally accepted th
Publikováno v:
Endocrinology 140 (1999) 7
Scopus-Elsevier
Endocrinology, 140(7), 3255-3263
Endocrinology, 140(7), 3255-3263. ENDOCRINE SOC
Scopus-Elsevier
Endocrinology, 140(7), 3255-3263
Endocrinology, 140(7), 3255-3263. ENDOCRINE SOC
Norepinephrine (NE) neurons within the nucleus tractus solitarii (NTS; A2 neurons) and ventrolateral medulla (A1 neurons) represent gonadal steroid-dependent components of several neural networks regulating reproduction. Previous studies have shown t
Publikováno v:
Endocrinology. 139:1420-1428
The sexually dimorphic profile of GH secretion is thought to be engendered by gonadal steroids acting in part on hypothalamic periventricular somatostatin (SOM) neurons. The present study set out to examine and characterize the development of sex dif
Publikováno v:
Neuroscience. 78:215-228
Circulating estrogens influence the electrical and biosynthetic activity of the hypothalamic magnocellular neurons which synthesize vasopressin or oxytocin and regulate body fluid homeostasis and reproduction. As none of these magnocellular neurons e