Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Sharon W. Lin"'
Autor:
Naomi S. Sta Maria, Leslie A. Khawli, Vyshnavi Pachipulusu, Sharon W. Lin, Long Zheng, Daniel Cohrs, Xiaodan Liu, Peisheng Hu, Alan L. Epstein, Russell E. Jacobs
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Quantitative in vivo monitoring of cell biodistribution offers assessment of treatment efficacy in real-time and can provide guidance for further optimization of chimeric antigen receptor (CAR) modified cell therapy. We evaluated the utility
Externí odkaz:
https://doaj.org/article/1a42eddcd18d4b17b25c6a34627d8118
Autor:
Sharon W. Lin, Russell E. Jacobs, Xiaodan Liu, Alan L. Epstein, Naomi S Sta Maria, Leslie A. Khawli, Peisheng Hu, Daniel Cohrs, Vyshnavi Pachipulusu, Long Zheng
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Quantitative in vivo monitoring of cell biodistribution offers assessment of treatment efficacy in real-time and can provide guidance for further optimization of chimeric antigen receptor (CAR) modified cell therapy. We evaluated the utility of a non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff014f49ad6df38662ec8e0ab69d078
https://doaj.org/article/1a42eddcd18d4b17b25c6a34627d8118
https://doaj.org/article/1a42eddcd18d4b17b25c6a34627d8118
Autor:
Irina Rozovsky, Sharon W. Lin, Caleb E. Finch, Todd E. Morgan, Jason M. Arimoto, Angela M. Wong
Publikováno v:
Endocrinology. 154:2101-2113
Rodent models show decreased neuronal responses to estradiol (E2) during aging (E2-desensitization) in association with reduced neuronal estrogen receptor (ER)-α, but little is known about age changes of E2-dependent astrocytic neurotrophic support.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4506ada433903512c1d12b3c8e40875d
https://doi.org/10.1210/en.2012-2046
https://doi.org/10.1210/en.2012-2046
Autor:
Anusha Jayaraman, Todd E. Morgan, Jenna C. Carroll, Roberta Diaz Brinton, M. Paul Murphy, Tina L. Beckett, Caleb E. Finch, Liqin Zhao, Sharon W. Lin, Jason M. Arimoto, Christian J. Pike
Publikováno v:
Endocrinology. 153:5467-5479
The accumulation of β-amyloid protein (Aβ) is a key risk factor in the development of Alzheimer's disease. The ovarian sex steroid hormones 17β-estradiol (E2) and progesterone (P4) have been shown to regulate Aβ accumulation, although the underly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a507a2d6ca3ac24bb87b00266bb14df5
https://doi.org/10.1210/en.2012-1464
https://doi.org/10.1210/en.2012-1464
Autor:
Roberta Diaz Brinton, Nahoko Iwata, Caleb E. Finch, Todd E. Morgan, Liqin Zhao, Jason M. Arimoto, Sharon W. Lin, Namrata Bali
Publikováno v:
Endocrinology. 153:759-769
Progesterone (P4) and estradiol (E2) modulate neurogenesis and synaptic remodeling in the hippocampus during the rat estrous cycle and in response to deafferenting lesions, but little is known about the steroidal regulation of hippocampal progesteron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce74349949b3a52075e2180b5c0d431
https://doi.org/10.1210/en.2011-1699
https://doi.org/10.1210/en.2011-1699
Publikováno v:
Journal of Biological Chemistry. 282:5582-5588
We recently discovered a novel signaling phenomenon involving a rapid and transient rise in intracellular low molecular weight iron complex(es) in activation of IkappaB kinase (IKK) in hepatic macrophages. We also showed direct treatment with ferrous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5731b81f076dcb8d225b4632f16f0c13
https://doi.org/10.1074/jbc.m609273200
https://doi.org/10.1074/jbc.m609273200
Autor:
Pietro Fratta, Janis McFerrin, W. King Engel, Valerie Askanas, Sharon W. Lin, Kelvin J.A. Davies
Publikováno v:
The American Journal of Pathology. 167:517-526
The 26S proteasome system is involved in eliminating various proteins, including ubiquitinated misfolded/unfolded proteins, and its inhibition results in cellular accumulation of protein aggregates. Intramuscle-fiber ubiquitinated multiprotein-aggreg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bed783077eb43f9388a0b284d14c53b1
https://doi.org/10.1016/s0002-9440(10)62994-x
https://doi.org/10.1016/s0002-9440(10)62994-x
Autor:
Sharon W Lin, James H. Doroshow, Cecile A. Donohue, Marianne Z. Metz, Susan E. Kane, Robert G. Lingeman, Linda Matsumoto
Publikováno v:
Biochemical Pharmacology. 62:693-704
The human multidrug resistance-1 gene (MDR1) is a dominant selectable and amplifiable marker in mammalian tissue culture cells. MDR1 is also being investigated as a gene therapy tool, both to protect normal cells against chemotherapy-related toxicity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5dc159a0526653a1deab8ee62cb20a25
https://doi.org/10.1016/s0006-2952(01)00727-4
https://doi.org/10.1016/s0006-2952(01)00727-4
Autor:
Robert H. Terbrueggen, Changjun Yu, Jon F. Kayyem, Daniel H. Farkas, Gary Blackburn, Yin-Peng Chen, Jost Vielmetter, Bruce D. Irvine, Sharon W. Lin, Handy Yowanto, Robert M. Umek
Publikováno v:
The Journal of Molecular Diagnostics. 3:74-84
A novel platform for the electronic detection of nucleic acids on microarrays is introduced and shown to perform well as a selective detection system for applications in molecular diagnostics. A gold electrode in a printed circuit board is coated wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fddbca1014a36436f8a32c7208ffe95c
https://doi.org/10.1016/s1525-1578(10)60655-1
https://doi.org/10.1016/s1525-1578(10)60655-1
Autor:
Todd E. Morgan, Zisu Mao, Roberta Diaz Brinton, Caleb E. Finch, Sharon W. Lin, Enrique Cadenas, Christian J. Pike, Wendy J. Mack, Liqin Zhao
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 2, p e31267 (2012)
PLoS ONE, Vol 7, Iss 2, p e31267 (2012)
This study investigated the impact of chronic exposure to continuous (CoP4) versus cyclic progesterone (CyP4) alone or in combination with 17β-estradiol (E2) on gene expression profiles targeting bioenergetics, metabolism and inflammation in the adu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c9cf2ff51e1089c216615e3e50e34a4
https://pubmed.ncbi.nlm.nih.gov/22393359
https://pubmed.ncbi.nlm.nih.gov/22393359