Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sharon Sawchak"'
Autor:
Inder Kaul, Sharon Sawchak, Amy Claxton, Colin Sauder, Howard H. Hassman, Rishi Kakar, David P. Walling, Leslie Citrome, Haiyuan Zhu, Andrew C. Miller, Stephen K. Brannan
Publikováno v:
Schizophrenia, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract In the 5-week, randomized, double-blind, placebo-controlled EMERGENT-1 (NCT03697252), EMERGENT-2 (NCT04659161), and EMERGENT-3 (NCT04738123) trials, xanomeline and trospium chloride (formerly known as KarXT) significantly improved symptoms o
Externí odkaz:
https://doaj.org/article/b60b332911db4c559f92ba32ff23af15
Autor:
Christoph U. Correll, Andrew C. Miller, Sharon Sawchak, Inder Kaul, Steven M. Paul, Stephen K. Brannan
Publikováno v:
CNS Spectrums. 28:220-220
IntroductionKarXT combines the M1/M4 preferring muscarinic receptor agonist xanomeline and the peripherally restricted anticholinergic trospium. In the phase 2 EMERGENT-1 study, KarXT met the primary endpoint of a significant reduction in Positive an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1eaeb71fd9018d92cb55d3930a3a471a
https://doi.org/10.1017/s1092852923001360
https://doi.org/10.1017/s1092852923001360
Autor:
Jeffrey A. Lieberman, Stephen K. Brannan, Sharon Sawchak, Steven M. Paul, Andrew C. Miller, Alan Breier
Publikováno v:
The New England journal of medicine. 384(25)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc0d1df758edff1fdd7fff9e2d990f1c
https://pubmed.ncbi.nlm.nih.gov/34161716
https://pubmed.ncbi.nlm.nih.gov/34161716
Autor:
Jeffrey A. Lieberman, Steven M. Paul, Sharon Sawchak, Andrew C. Miller, Alan Breier, Stephen K. Brannan
Publikováno v:
N Engl J Med
BACKGROUND: The muscarinic receptor agonist xanomeline has antipsychotic properties and is devoid of dopamine receptor–blocking activity but causes cholinergic adverse events. Trospium is a peripherally restricted muscarinic receptor antagonist tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0cebcf6c8f06c4b3bcc4e20ec7964cd
https://pubmed.ncbi.nlm.nih.gov/34161715
https://pubmed.ncbi.nlm.nih.gov/34161715
Publikováno v:
Biological Psychiatry. 87:S169
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fd224af0f93e07f04df1229391c14fa
https://doi.org/10.1016/j.biopsych.2020.02.446
https://doi.org/10.1016/j.biopsych.2020.02.446
Autor:
Gary E. Landreth, Suzanne Craft, Ülla Linnamägi, Sally Egginton, Sharon Sawchak, Marina Zvartau-Hind, Claire Alderton, Michael Gold, Ann M. Saunders, Michael C. Irizarry
Publikováno v:
Dementia and Geriatric Cognitive Disorders. 30:131-146
Background/Aims: A phase II study of the peroxisome proliferator-activated receptor-γ agonist rosiglitazone extended release (RSG XR) in mild-to-moderate Alzheimer’s disease (AD) detected a treatment benefit to cognition in apolipoprotein E(APOE)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e364c78d2572c1be6bea8c237d9ba75f
https://doi.org/10.1159/000318845
https://doi.org/10.1159/000318845
Autor:
Gary E. Landreth, Suzanne Craft, Claire Alderton, Sharon Sawchak, Michael Gold, Ülla Linnamägi, Marina Zvartau-Hind, Ann M. Saunders, Sally Y. Ritchie
Publikováno v:
Alzheimer's & Dementia. 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11db48cef2e6655bf1f2f46f557b79e2
https://doi.org/10.1016/j.jalz.2009.05.219
https://doi.org/10.1016/j.jalz.2009.05.219
Autor:
Carl Chiang, Ann M. Saunders, Christopher H. van Dyck, John T. Davies, Michael Gold, Sharon Sawchak, Conn M. Harrington, Michael C. Irizarry, Marina Zvartau-Hind
Publikováno v:
Alzheimer's & Dementia. 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2149ee614635d7a2e52924d3d7dc8336
https://doi.org/10.1016/j.jalz.2009.07.079
https://doi.org/10.1016/j.jalz.2009.07.079
Autor:
Gary E. Landreth, Ülla Linnamägi, Marina Zvartau-Hind, Ann M. Saunders, Claire Alderton, Michael Gold, Sally Y. Ritchie, Sharon Sawchak, Suzanne Craft
Publikováno v:
Alzheimer's & Dementia. 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b80010c3970e50135931b3972057bdc
https://doi.org/10.1016/j.jalz.2009.04.271
https://doi.org/10.1016/j.jalz.2009.04.271
Autor:
Suzanne Craft, Claire Alderton, Michael C. Irizarry, Marina Zvartau-Hind, Gary E. Landreth, Michael Gold, Ann M. Saunders, Sally Y. Ritchie, Ülla Linnamägi, Sharon Sawchak
Publikováno v:
Alzheimer's & Dementia. 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5fb904ebb57a0ec38d4da50dbfb7b3c6
https://doi.org/10.1016/j.jalz.2009.04.252
https://doi.org/10.1016/j.jalz.2009.04.252