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pro vyhledávání: '"Sharon S. Rowland"'
Publikováno v:
FEMS Microbiology Letters. 151:59-64
Autor:
Sharon S. Rowland
Publikováno v:
Drug Information Journal. 35:993-1001
Transmissible spongiform encephalopathy (TSE) is an inclusive term for a group of slowly progressing, neurodegenerative diseases with long incubation periods. Design and validation of manufacturing processes that eliminate TSE agents is difficult bec
Publikováno v:
FEMS Immunology and Medical Microbiology. 23:21-25
Mycobacterial polypeptides from 2 kDa to 14 kDa may be involed in host response to infection and be useful for new diagnostics and vaccines. Tris-tricine SDS-polyacrylamide gel electrophoresis separation of proteins in tuberculin purified protein der
Publikováno v:
Microbiology and Immunology. 40:883-886
Murine monoclonal antibodies were produced against Mycobacterium tuberculosis (Mtb) using standard hybridoma procedures. By a whole cell enzyme-linked immunosorbent assay (ELISA), one monoclonal antibody (mAb), HB28, demonstrated high level specific
Publikováno v:
Tuberculosis (Edinburgh, Scotland). 85(1-2)
This article discusses the steps required to file an investigational new drug (IND) application to the United States Food and Drug Administration (FDA) and begin a Phase I trial of a new tuberculosis vaccine in the US. Many different groups play a ro
Autor:
Malathi Sathyamoorthy, Marilyn K. Speedie, Sharon S. Rowland, Burton M. Pogell, James J. Zulty
Publikováno v:
Applied Microbiology and Biotechnology. 38
A heterologous phosphotriesterase (parathion hydrolase) containing the native Flavobacterium species signal sequence was previously shown to be secreted by Streptomyces lividans. Western blot analysis of the recombinant phosphotriesterase produced by
Publikováno v:
The Journal of steroid biochemistry and molecular biology. 42(7)
A constitutive estrogen-binding protein (EBP) has been identified in the cytosol of Pseudomonas aeruginosa, a Gram-negative bacterium. All 14 strains tested contained the EBP. Estradiol binding was rapid and maximal binding occurred by 90 min at 0 de
A heterologous phosphotriesterase (parathion hydrolase), previously cloned from a Flavobacterium species into Streptomyces lividans, was secreted at high levels and purified to homogeneity. N-terminal analysis revealed that it had been processed in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec64976427b7bdbd5bba55bceddd8149
https://europepmc.org/articles/PMC182729/
https://europepmc.org/articles/PMC182729/
Publikováno v:
Applied and Environmental Microbiology. 57:610-611
Pure recombinant Flavobacterium parathion hydrolase (an organophosphorus acid anhydrase) from Streptomyces lividans was found to hydrolyze the toxic nerve agent soman at only 0.1% of the rate observed with parathion as substrate. Studies with wild-ty