Comparison of Approaches for Measuring Adherence and Persistence to Oral Oncologic Therapies in Patients Diagnosed with Metastatic Renal Cell Carcinoma

Autor: Danielle S. Chun, Blánaid Hicks, Sharon Peacock Hinton, Michele Jonsson Funk, Kyna Gooden, Alexander P. Keil, Hung-Jui Tan, Til Stürmer, Jennifer L. Lund

Publikováno v: Chun, D, Hicks, B, Hinton, S P, Jonsson Funk, M, Gooden, K, Keil, A P, Tan, H-J, Sturmer, T & Lund, J L 2022, ' Comparison of approaches for measuring adherence and persistence to oral oncologic therapies in patients diagnosed with metastatic renal cell carcinoma ', Cancer Epidemiology Biomarkers & Prevention . https://doi.org/10.1158/1055-9965.EPI-21-0341

Background: Adherence and persistence studies face several methodologic difficulties, including short-term mortality. We compared approaches to quantify adherence and persistence to first line (1L) oral targeted therapy (TT) in patients diagnosed wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f446d2ca0a4fd74c371b23c65635d29
https://doi.org/10.1158/1055-9965.epi-21-0341

Effectiveness of adjuvant FOLFOX vs 5FU / LV in adults over age 65 with stage II and III colon cancer using a novel hybrid approach

Autor: Sharon Peacock Hinton, Til Stürmer, Shahar Shmuel, Hanna K. Sanoff, Michael Webster-Clark, Jennifer L. Lund

Publikováno v: Pharmacoepidemiology and Drug Safety. 29:1579-1587

Purpose Estimates of cancer therapy effects can differ in clinical trials and clinical practice, partly due to underrepresentation of certain patient subgroups in trials. We utilize a hybrid approach, combining clinical trial and real-world data, to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::660b5a46dfeff794b55786b2e569f50b
https://doi.org/10.1002/pds.5148

Patterns of first-line targeted therapy utilization and adherence among older adults diagnosed with metastatic renal cell carcinoma

Autor: Jennifer L. Lund, Christine D. Hsu, Blánaid Hicks, Sharon Peacock Hinton, Hung-Jui Tan, Danielle S. Chun

Publikováno v: Hicks, B M, Chun, D S, Hinton, S P, Hsu, C D, Tan, H-J & Lund, J L 2021, ' Patterns of first-line targeted therapy utilization and adherence among older adults diagnosed with metastatic renal cell carcinoma ', Journal of Geriatric Oncology . https://doi.org/10.1016/j.jgo.2021.11.006

BackgroundDespite the rapid approval of targeted therapies for metastatic renal cell carcinoma (mRCC) evidence on real world treatment patterns remains limited. This study evaluated patterns of first-line targeted therapy utilization and adherence in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8064287788a9e90ebc47353807e88237
https://pure.qub.ac.uk/en/publications/e1c9c374-166a-4b29-b51a-50811deec30a

Comparative Effectiveness and Harms of Antibiotics for Outpatient Diverticulitis : Two Nationwide Cohort Studies

Autor: Luther A. Bartelt, Jessie K. Edwards, Alan C Kinlaw, Jennifer L. Lund, Virginia Pate, Robert S. Sandler, Sharon Peacock Hinton, Charles Gaber, Til Stürmer, Anne F. Peery

Publikováno v: Ann Intern Med

Background Outpatient diverticulitis is commonly treated with either a combination of metronidazole and a fluoroquinolone (metronidazole-with-fluoroquinolone) or amoxicillin-clavulanate alone. The U.S. Food and Drug Administration advised that fluoro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::810d9ee93eee5b1ab455ff23bb9e56f2
https://pubmed.ncbi.nlm.nih.gov/35286833

Acute pancreatitis as an early marker of pancreatic cancer and cancer stage, treatment, and prognosis

Autor: Deirdre Cronin-Fenton, Morten Ladekarl, Sharon Peacock Hinton, Uffe Heide-Jørgensen, Jakob Kirkegård, Frank Viborg Mortensen, Jennifer L. Lund, Charles Gaber

Publikováno v: Kirkegård, J, Gaber, C, Lund, J L, Hinton, S P, Ladekarl, M, Heide-Jørgensen, U, Cronin-Fenton, D & Mortensen, F V 2020, ' Acute pancreatitis as an early marker of pancreatic cancer and cancer stage, treatment, and prognosis ', Cancer epidemiology, vol. 64, 101647 . https://doi.org/10.1016/j.canep.2019.101647
Cancer Epidemiol

BACKGROUND: We aimed to examine the association between acute pancreatitis, a potential early symptom of pancreatic cancer, and pancreatic cancer stage, treatment, and prognosis.METHODS: We conducted a cohort study of patients diagnosed with pancreat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd0c242f1c81c28b1bf1395b4ccb5891
https://pure.au.dk/portal/da/publications/acute-pancreatitis-as-an-early-marker-of-pancreatic-cancer-and-cancer-stage-treatment-and-prognosis(bf1d9d58-9c68-421b-b290-5c9d5a2d83c3).html