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of 32
pro vyhledávání: '"Sharon Min"'
Publikováno v:
BMC Medical Education, Vol 22, Iss 1, Pp 1-7 (2022)
Abstract Background Language proficiency is crucial for doctors as they communicate with patients, peers and other healthcare professionals. Although proficiency in English is part of admission requirements, there is a gap in the knowledge of medical
Externí odkaz:
https://doaj.org/article/39c0680d616344f195b153bf176a6026
Autor:
Sharon Min Qi Chee, Jantana Wongsantichon, Lau Sze Yi, Barindra Sana, Yuri Frosi, Robert C. Robinson, Farid J. Ghadessy
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Grafting bioactive peptides into recipient protein scaffolds can often increase their activities by conferring enhanced stability and cellular longevity. Here, we describe use of vGFP as a novel scaffold to display peptides. vGFP comprises G
Externí odkaz:
https://doaj.org/article/bb66fff127b041c1baa2825939769763
Autor:
Chee, Sharon Min Qi1, Wongsantichon, Jantana2, Yi, Lau Sze1, Sana, Barindra1, Frosi, Yuri1, Robinson, Robert C.3,4, Ghadessy, Farid J.1 fghadessy@p53Lab.a-star.edu.sg
Publikováno v:
Scientific Reports. 5/12/2021, Vol. 11 Issue 1, p1-13. 13p.
Structure-activity studies of Mdm2/Mdm4-binding stapled peptides comprising non-natural amino acids.
Autor:
Chee, Sharon Min Qi1, Wongsantichon, Jantana2, Siau, Jiawei1, Thean, Dawn1, Ferrer, Fernando1, Robinson, Robert C.2, Lane, David P.1, Brown, Christopher J.1 cjbrown@p53Lab.a-star.edu.sg, Ghadessy, Farid J.1 fghadessy@p53Lab.a-star.edu.sg
Publikováno v:
PLoS ONE. 12/11/2017, Vol. 12 Issue 12, p1-15. 15p.
Structure-activity studies of Mdm2/Mdm4-binding stapled peptides comprising non-natural amino acids.
Autor:
Sharon Min Qi Chee, Jantana Wongsantichon, Jiawei Siau, Dawn Thean, Fernando Ferrer, Robert C Robinson, David P Lane, Christopher J Brown, Farid J Ghadessy
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0189379 (2017)
As primary p53 antagonists, Mdm2 and the closely related Mdm4 are relevant cancer therapeutic targets. We have previously described a series of cell-permeable stapled peptides that bind to Mdm2 with high affinity, resulting in activation of the p53 t
Externí odkaz:
https://doaj.org/article/fdc2d7bd24ff4e5e8f8b236a8417e65d
Akademický článek
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Additional file 1: Table S1. Sample of Codes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77ebb2b10d4083b42316c525ac256e13
Background Language proficiency is crucial for doctors as they communicate with patients, peers and other healthcare professionals. Although proficiency in English is part of admission requirements, there is a gap of knowledge on medical students’
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dd08b5a5f60c29a0920126534e8532c8
https://doi.org/10.21203/rs.3.rs-657183/v1
https://doi.org/10.21203/rs.3.rs-657183/v1
Autor:
Sharon Min Qi Chee, Jantana Wongsantichon, Quah Soo Tng, Robert Robinson, Thomas L Joseph, Chandra Verma, David P Lane, Christopher J Brown, Farid J Ghadessy
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e104914 (2014)
As key negative regulator of the p53 tumour suppressor, Mdm2 is an attractive therapeutic target. Small molecules such as Nutlin have been developed to antagonise Mdm2, resulting in p53-dependent death of tumour cells. We have recently described a mu
Externí odkaz:
https://doaj.org/article/75e1615ecfa7434bab2588d9679c1fc7
Autor:
Sharon Min, Karen A. Ingraham, Jianzhong Huang, Pan Chan, Steve Rittenhouse, Nicole E. Scangarella-Oman
Publikováno v:
Open Forum Infectious Diseases
Background Gepotidacin (GEP) is a novel triazaacenaphthylene bacterial type II topoisomerase inhibitor targeting both bacterial DNA gyrase and topoisomerase IV by a different mechanism from fluoroquinolone antibiotics. Although in vitro frequency of