Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sharon Mexal"'
Autor:
Sharon Mexal, Marisa Marsolek, Sheila I.B. Maier, Jerry A. Stitzel, William J. Horton, Eric L. Crouch, Andra L. Wilkinson
Publikováno v:
Neuropharmacology. 63:966-973
Despite the evidence that there is a daily rhythm in smoking behavior and that the effects of drugs of abuse exhibit diurnal variations, very few studies have explored the extent to which sensitivity to the effects of nicotine vary over the course of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b88c5bf1eedccc04d01a7eb77ec8226
https://doi.org/10.1016/j.neuropharm.2012.06.065
https://doi.org/10.1016/j.neuropharm.2012.06.065
Publikováno v:
Journal of Molecular Neuroscience. 40:185-195
The alpha7 neuronal nicotinic receptor gene (CHRNA7) has been implicated in the pathophysiology of schizophrenia by genetic and pharmacological studies. Expression of the alpha7* receptor, as measured by [(125)I]alpha-bungarotoxin autoradiography, is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c9097f5dc5993bf7401660e35eaeee8
https://doi.org/10.1007/s12031-009-9233-4
https://doi.org/10.1007/s12031-009-9233-4
Autor:
Philip Y. T. Liu, David Feifel, Joseph R. Goldenberg, Sharon Mexal, Paul D. Shilling, Gilia Melendez
Publikováno v:
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, vol 34, iss 8
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Cognitive deficits in schizophrenia are a major source of dysfunction for which more effective treatments are needed. The vasopressin-deficient Brattleboro (BRAT) rat has been shown to have several natural schizophrenia-like deficits, including impai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5b58e8bf420623bebf39881dc4c276
https://doi.org/10.1038/npp.2009.15
https://doi.org/10.1038/npp.2009.15
Publikováno v:
Journal of Dual Diagnosis. 3:43-59
Schizophrenia is a common mental illness with a high prevalence of smoking. More than 80% of schizophrenics smoke compared to 25% of the general population. Both schizophrenia and tobacco use have strong genetic components, which may overlap. It has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7998ae09f9f3a5ad4378c7911ff7ec0c
https://doi.org/10.1300/j374v03n03_05
https://doi.org/10.1300/j374v03n03_05
Autor:
Paul M. Jenkins, Jerry A. Stitzel, Eric L. Crouch, Meeghan A. Lautner, Sharon Mexal, Eli Iacob
Publikováno v:
Journal of Biological Chemistry. 282:13220-13227
Inbred mouse strains display significant differences in their levels of brain alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) expression, as measured by binding of the alpha7-selective antagonist alpha-bungarotoxin. Variations in alpha-bungaro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c50668084f7b18526771598928fd5d6
https://doi.org/10.1074/jbc.m610694200
https://doi.org/10.1074/jbc.m610694200
Studies using the radio-labeled nicotinic receptor antagonist [(125)I]-alpha-bungarotoxin, which binds to alpha7 subunit containing nicotinic receptors, have demonstrated that mouse strains vary considerably in the number of alpha7-containing nicotin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3faa592a47f1a50812b6a189e3d390a
https://europepmc.org/articles/PMC2670961/
https://europepmc.org/articles/PMC2670961/
Publikováno v:
Journal of dual diagnosis. 3(3-4)
Schizophrenia is a common mental illness with a high prevalence of smoking. More than 80% of schizophrenics smoke compared to 25% of the general population. Both schizophrenia and tobacco use have strong genetic components, which may overlap. It has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::94e0482e2164824cae3a331bbde4b6a8
https://pubmed.ncbi.nlm.nih.gov/19122786
https://pubmed.ncbi.nlm.nih.gov/19122786
Publikováno v:
Genetic epidemiology. 32(1)
The aim of this paper is to generalize permutation methods for multiple testing adjustment of significant partial regression coefficients in a linear regression model used for microarray data. Using a permutation method outlined by Anderson and Legen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22fa436771288e59c5e28d835f56be83
https://pubmed.ncbi.nlm.nih.gov/17630650
https://pubmed.ncbi.nlm.nih.gov/17630650
Publikováno v:
Biochemical Pharmacology. 82:1046-1047
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d4881b626987047b4a683daf47c3cbd
https://doi.org/10.1016/j.bcp.2011.07.060
https://doi.org/10.1016/j.bcp.2011.07.060
Autor:
Elizabeth C. Chao, Elaine Chen, John Copenhaver, Tina Pesaran, A. J. Stuenkel, Sharon Mexal, Robert Hoiness, Jill Cook, Holly LaDuca, Hong Lu, Chia-Ling Gau, Jill M. Siegfried
Publikováno v:
Cancer Research. 74:14-14
The multi-gene hereditary cancer panel testing approach allows for the identification of probands carrying multiple mutations in hereditary cancer predisposition genes. The purpose of this study is to assess the frequency and phenotypes of individual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ac9df44d3b6a0f6cf8fcf42a15ff2f3
https://doi.org/10.1158/1538-7445.cansusc14-14
https://doi.org/10.1158/1538-7445.cansusc14-14