Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Sharon M. Landers"'
Autor:
Angela D. Bhalla, Sharon M. Landers, Anand K. Singh, Jace P. Landry, Michelle G. Yeagley, Gabryella S.B. Myerson, Cristian B. Delgado-Baez, Stephanie Dunnand, Theresa Nguyen, Xiaoyan Ma, Svetlana Bolshakov, Brian A. Menegaz, Salah-Eddine Lamhamedi-Cherradi, Xizeng Mao, Xingzhi Song, Alexander J. Lazar, Ian E. McCutcheon, John M. Slopis, Joseph A. Ludwig, Dina C. Lev, Kunal Rai, Keila E. Torres
Publikováno v:
Laboratory Investigation. 102:658-666
Undifferentiated pleomorphic sarcoma (UPS) and malignant peripheral nerve sheath tumor (MPNST) are aggressive soft tissue sarcomas that do not respond well to current treatment modalities. The limited availability of UPS and MPNST cell lines makes it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::106412c15f0eb3db9b44d44608db21c1
https://doi.org/10.1038/s41374-022-00734-6
https://doi.org/10.1038/s41374-022-00734-6
Autor:
Salah-Eddine Lamhamedi-Cherradi, Svetlana Bolshakov, Wei-Lien Wang, Kunal Rai, Dunnand S, John M. Slopis, Alexander J. Lazar, Delgado-Baez Cb, Michelle G. Yeagley, Katarzyna Tomczak, Xizeng Mao, Dina Lev, Zachary A. Mulder, Kochat, Joseph A. Ludwig, Ian E. McCutcheon, Anand K Singh, Jianhua Zhang, Davis R. Ingram, Meyerson Gsb, Brian A. Menegaz, Xingzhi Song, Keila E. Torres, Sharon M. Landers, Xingdi Ma, Angela D. Bhalla, Tri H. Nguyen, Hannah C. Beird
Undifferentiated pleomorphic sarcoma (UPS) and malignant peripheral nerve sheath tumor (MPNST) are aggressive soft tissue sarcomas that do not respond well to current treatment modalities. The limited availability of UPS and MPNST cell lines makes it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50472ecc879af0f10407731aca428d3c
https://doi.org/10.1101/2021.05.13.443902
https://doi.org/10.1101/2021.05.13.443902
Autor:
Veena, Kochat, Ayush T, Raman, Sharon M, Landers, Ming, Tang, Jonathan, Schulz, Christopher, Terranova, Jace P, Landry, Angela D, Bhalla, Hannah C, Beird, Chia-Chin, Wu, Yingda, Jiang, Xizeng, Mao, Rossana, Lazcano, Swati, Gite, Davis R, Ingram, Min, Yi, Jianhua, Zhang, Emily Z, Keung, Christopher P, Scally, Christina L, Roland, Kelly K, Hunt, Barry W, Feig, P Andrew, Futreal, Patrick, Hwu, Wei-Lien, Wang, Alexander J, Lazar, John M, Slopis, Heather, Wilson-Robles, Dominique J, Wiener, Ian E, McCutcheon, Brandan, Wustefeld-Janssens, Kunal, Rai, Keila E, Torres
Publikováno v:
Acta neuropathologica. 142(3)
Malignant peripheral nerve sheath tumors (MPNSTs) are soft tissue sarcomas that frequently harbor genetic alterations in polycomb repressor complex 2 (PRC2) components-SUZ12 and EED. Here, we show that PRC2 loss confers a dedifferentiated early neura
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f12a1c12bcba857b28a6e1ce8e336026
https://pubmed.ncbi.nlm.nih.gov/34283254
https://pubmed.ncbi.nlm.nih.gov/34283254
Autor:
Keila E. Torres, Xiaoyan Ma, Angela D. Bhalla, Davis R. Ingram, Sharon M. Landers, Alexander J. Lazar, Wei-Lien Wang, Ghadah A. Al Sannaa, Kristelle Lusby
Publikováno v:
Journal of cancer science and clinical therapeutics
Dysregulation of the receptor tyrosine kinase AXL is known to promote cancer cell growth and survival in many sarcomas, including the rare subtype, malignant peripheral nerve sheath tumors (MPNST). MPNSTs are largely chemoresistant and carry a poor p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7153cc0ff712c7a4a52098fbd19762e2
https://doi.org/10.26502/jcsct.5079091
https://doi.org/10.26502/jcsct.5079091
Autor:
Davis R. Ingram, Alexander J. Lazar, Caitlin D. May, Xiao Yan Ma, Keila E. Torres, Kelsey L. Watson, Svetlana Bolshakov, Sharon M. Landers, Christine M. Kivlin, Angela D. Bhalla, Ghadah A. Al Sannaa, Wei-Lien Wang
Publikováno v:
Cancer Biology & Therapy
Undifferentiated pleomorphic sarcomas (UPSs) are aggressive mesenchymal malignancies with no definitive cell of origin or specific recurrent genetic hallmarks. These tumors are largely chemoresistant; thus, identification of potential therapeutic tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba19802a344d2b1ab4b77dd95642a8b7
http://europepmc.org/articles/PMC5678691
http://europepmc.org/articles/PMC5678691
Autor:
Sean P. Dineen, Sharon M. Landers, Kelly K. Hunt, Wei Lien Wang, Alexander J. Lazar, Caitlin D. May, Davis R. Ingram, Kelsey L. Watson, Christina L. Roland, Keila E. Torres, Ghadah A. Al Sannaa, B. Ashleigh Guadagnolo, Barry W. Feig, Rachel Feig, Janice N. Cormier
Publikováno v:
Annals of Surgical Oncology. 23:2220-2228
Undifferentiated pleomorphic sarcomas (UPS) present a diagnostic and therapeutic challenge. Identification of prognostic molecular markers is required for the discovery of novel treatment approaches. The purpose of this study was to correlate clinico
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eaa1fc30733b783e4bd469a9f643fea8
https://doi.org/10.1245/s10434-016-5115-5
https://doi.org/10.1245/s10434-016-5115-5
Autor:
Davis R. Ingram, Zachary A. Mulder, Sharon M. Landers, Keila E. Torres, Ayush T. Raman, Michelle G. Yeagley, Jace P. Landry, Erica L. Gardenhire, Angela D. Bhalla, Gabryella S. Serrao, Kunal Rai, Wei-Lien Wang, Christopher Terranova, S. Carson Callahan, John M. Slopis, Ian E. McCutcheon, Katarzyna Tomczak, Alexander J. Lazar, Christine B. Peterson
Publikováno v:
Cancer Research. 80:1248-1248
Malignant peripheral nerve sheath tumors (MPNSTs) are a highly aggressive soft tissue sarcoma affecting approximately 10-15% of individuals with neurofibromatosis type 1 (NF1). MPNST development is characterized by an altered DNA methylation landscap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d52cbad8c95685687ccbc63fc1cfbf06
https://doi.org/10.1158/1538-7445.am2020-1248
https://doi.org/10.1158/1538-7445.am2020-1248
Autor:
Keila E. Torres, Ian E. McCutcheon, Alexandar J. Lazar, Kelly K. Hunt, Sharon M. Landers, Christina L. Roland, Ghadah A. Al Sannaa, Wei Lien Wang, Kelsey L. Watson, B. Ashleigh Guadagnolo, Barry W. Feig, Janice N. Cormier, Christine M. Kivlin, Davis R. Ingram, Andrew J. Bishop, John M. Slopis
OBJECTIVE Malignant peripheral nerve sheath tumors (MPNSTs) are an aggressive group of soft tissue sarcomas that can arise sporadically, in the context of neurofibromatosis Type 1 (NF1) or at a site of prior irradiation. Large series profiling the fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa8c313c6639a34e666e0d4037f2bd4
https://europepmc.org/articles/PMC5045773/
https://europepmc.org/articles/PMC5045773/
Publikováno v:
Eukaryotic cell. 8(7)
Intracellular and intercellular polarity requires that specific proteins be sorted to discreet locations within and between cells. One mechanism for sorting proteins is through RNA localization. In Saccharomyces cerevisiae , ASH1 mRNA localizes to th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::588306cc125b2f65652a0ebd51895e7d
https://pubmed.ncbi.nlm.nih.gov/19429778
https://pubmed.ncbi.nlm.nih.gov/19429778
Nonsense-mediated mRNA decay (NMD) performs two functions in eukaryotes, one in controlling the expression level of a substantial subset of genes and the other in RNA surveillance. In the vast majority of genes, nonsense mutations render the correspo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d95df3aa803ad0e25edb6573c52ea1
https://europepmc.org/articles/PMC2581943/
https://europepmc.org/articles/PMC2581943/