Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Sharon M. Gorski"'
Autor:
Marie Morimoto, Vikas Bhambhani, Nour Gazzaz, Mariska Davids, Paalini Sathiyaseelan, Ellen F. Macnamara, Jennifer Lange, Anna Lehman, Patricia M. Zerfas, Jennifer L. Murphy, Maria T. Acosta, Camille Wang, Emily Alderman, Undiagnosed Diseases Network, Sara Reichert, Audrey Thurm, David R. Adams, Wendy J. Introne, Sharon M. Gorski, Cornelius F. Boerkoel, William A. Gahl, Cynthia J. Tifft, May Christine V. Malicdan
Publikováno v:
npj Genomic Medicine, Vol 8, Iss 1, Pp 1-16 (2023)
Abstract Autophagy regulates the degradation of damaged organelles and protein aggregates, and is critical for neuronal development, homeostasis, and maintenance, yet few neurodevelopmental disorders have been associated with pathogenic variants in g
Externí odkaz:
https://doaj.org/article/26c827d9dfcc46b4ace723c7df39bf58
Autor:
Kevin C. Yang, Sharon M. Gorski
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101283- (2022)
Summary: RNA-sequencing and quantitative proteomic profiling simultaneously measure thousands of molecules and provide opportunities to decipher the transcriptomic and proteomic landscapes of cohort specimens for basic and health research. We present
Externí odkaz:
https://doaj.org/article/4fe8dce9ce3b43f1832816ec18e1139e
Autor:
Chandra Lebovitz, Nicole Wretham, Maryam Osooly, Katy Milne, Tia Dash, Shelby Thornton, Basile Tessier-Cloutier, Paalini Sathiyaseelan, Svetlana Bortnik, Nancy Erro Go, Elizabeth Halvorsen, Rachel A. Cederberg, Norman Chow, Nancy Dos Santos, Kevin L. Bennewith, Brad H. Nelson, Marcel B. Bally, Wan L. Lam, Sharon M. Gorski
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Pathological links between neurodegenerative disease and cancer are emerging. LRRK2 overactivity contributes to Parkinson’s disease, whereas our previous analyses of public cancer patient data revealed that decreased LRRK2 expression is as
Externí odkaz:
https://doaj.org/article/a628231eefc547ca89a67c8ce3fcdf31
Autor:
Clotilde Théry, Kenneth W Witwer, Elena Aikawa, Maria Jose Alcaraz, Johnathon D Anderson, Ramaroson Andriantsitohaina, Anna Antoniou, Tanina Arab, Fabienne Archer, Georgia K Atkin-Smith, D Craig Ayre, Jean-Marie Bach, Daniel Bachurski, Hossein Baharvand, Leonora Balaj, Shawn Baldacchino, Natalie N Bauer, Amy A Baxter, Mary Bebawy, Carla Beckham, Apolonija Bedina Zavec, Abderrahim Benmoussa, Anna C Berardi, Paolo Bergese, Ewa Bielska, Cherie Blenkiron, Sylwia Bobis-Wozowicz, Eric Boilard, Wilfrid Boireau, Antonella Bongiovanni, Francesc E Borràs, Steffi Bosch, Chantal M Boulanger, Xandra Breakefield, Andrew M Breglio, Meadhbh Á Brennan, David R Brigstock, Alain Brisson, Marike LD Broekman, Jacqueline F Bromberg, Paulina Bryl-Górecka, Shilpa Buch, Amy H Buck, Dylan Burger, Sara Busatto, Dominik Buschmann, Benedetta Bussolati, Edit I Buzás, James Bryan Byrd, Giovanni Camussi, David RF Carter, Sarah Caruso, Lawrence W Chamley, Yu-Ting Chang, Chihchen Chen, Shuai Chen, Lesley Cheng, Andrew R Chin, Aled Clayton, Stefano P Clerici, Alex Cocks, Emanuele Cocucci, Robert J Coffey, Anabela Cordeiro-da-Silva, Yvonne Couch, Frank AW Coumans, Beth Coyle, Rossella Crescitelli, Miria Ferreira Criado, Crislyn D’Souza-Schorey, Saumya Das, Amrita Datta Chaudhuri, Paola de Candia, Eliezer F De Santana, Olivier De Wever, Hernando A del Portillo, Tanguy Demaret, Sarah Deville, Andrew Devitt, Bert Dhondt, Dolores Di Vizio, Lothar C Dieterich, Vincenza Dolo, Ana Paula Dominguez Rubio, Massimo Dominici, Mauricio R Dourado, Tom AP Driedonks, Filipe V Duarte, Heather M Duncan, Ramon M Eichenberger, Karin Ekström, Samir EL Andaloussi, Celine Elie-Caille, Uta Erdbrügger, Juan M Falcón-Pérez, Farah Fatima, Jason E Fish, Miguel Flores-Bellver, András Försönits, Annie Frelet-Barrand, Fabia Fricke, Gregor Fuhrmann, Susanne Gabrielsson, Ana Gámez-Valero, Chris Gardiner, Kathrin Gärtner, Raphael Gaudin, Yong Song Gho, Bernd Giebel, Caroline Gilbert, Mario Gimona, Ilaria Giusti, Deborah CI Goberdhan, André Görgens, Sharon M Gorski, David W Greening, Julia Christina Gross, Alice Gualerzi, Gopal N Gupta, Dakota Gustafson, Aase Handberg, Reka A Haraszti, Paul Harrison, Hargita Hegyesi, An Hendrix, Andrew F Hill, Fred H Hochberg, Karl F Hoffmann, Beth Holder, Harry Holthofer, Baharak Hosseinkhani, Guoku Hu, Yiyao Huang, Veronica Huber, Stuart Hunt, Ahmed Gamal-Eldin Ibrahim, Tsuneya Ikezu, Jameel M Inal, Mustafa Isin, Alena Ivanova, Hannah K Jackson, Soren Jacobsen, Steven M Jay, Muthuvel Jayachandran, Guido Jenster, Lanzhou Jiang, Suzanne M Johnson, Jennifer C Jones, Ambrose Jong, Tijana Jovanovic-Talisman, Stephanie Jung, Raghu Kalluri, Shin-ichi Kano, Sukhbir Kaur, Yumi Kawamura, Evan T Keller, Delaram Khamari, Elena Khomyakova, Anastasia Khvorova, Peter Kierulf, Kwang Pyo Kim, Thomas Kislinger, Mikael Klingeborn, David J Klinke, Miroslaw Kornek, Maja M Kosanović, Árpád Ferenc Kovács, Eva-Maria Krämer-Albers, Susanne Krasemann, Mirja Krause, Igor V Kurochkin, Gina D Kusuma, Sören Kuypers, Saara Laitinen, Scott M Langevin, Lucia R Languino, Joanne Lannigan, Cecilia Lässer, Louise C Laurent, Gregory Lavieu, Elisa Lázaro-Ibáñez, Soazig Le Lay, Myung-Shin Lee, Yi Xin Fiona Lee, Debora S Lemos, Metka Lenassi, Aleksandra Leszczynska, Isaac TS Li, Ke Liao, Sten F Libregts, Erzsebet Ligeti, Rebecca Lim, Sai Kiang Lim, Aija Linē, Karen Linnemannstöns, Alicia Llorente, Catherine A Lombard, Magdalena J Lorenowicz, Ákos M Lörincz, Jan Lötvall, Jason Lovett, Michelle C Lowry, Xavier Loyer, Quan Lu, Barbara Lukomska, Taral R Lunavat, Sybren LN Maas, Harmeet Malhi, Antonio Marcilla, Jacopo Mariani, Javier Mariscal, Elena S Martens-Uzunova, Lorena Martin-Jaular, M Carmen Martinez, Vilma Regina Martins, Mathilde Mathieu, Suresh Mathivanan, Marco Maugeri, Lynda K McGinnis, Mark J McVey, David G Meckes, Katie L Meehan, Inge Mertens, Valentina R Minciacchi, Andreas Möller, Malene Møller Jørgensen, Aizea Morales-Kastresana, Jess Morhayim, François Mullier, Maurizio Muraca, Luca Musante, Veronika Mussack, Dillon C Muth, Kathryn H Myburgh, Tanbir Najrana, Muhammad Nawaz, Irina Nazarenko, Peter Nejsum, Christian Neri, Tommaso Neri, Rienk Nieuwland, Leonardo Nimrichter, John P Nolan, Esther NM Nolte-’t Hoen, Nicole Noren Hooten, Lorraine O’Driscoll, Tina O’Grady, Ana O’Loghlen, Takahiro Ochiya, Martin Olivier, Alberto Ortiz, Luis A Ortiz, Xabier Osteikoetxea, Ole Østergaard, Matias Ostrowski, Jaesung Park, D. Michiel Pegtel, Hector Peinado, Francesca Perut, Michael W Pfaffl, Donald G Phinney, Bartijn CH Pieters, Ryan C Pink, David S Pisetsky, Elke Pogge von Strandmann, Iva Polakovicova, Ivan KH Poon, Bonita H Powell, Ilaria Prada, Lynn Pulliam, Peter Quesenberry, Annalisa Radeghieri, Robert L Raffai, Stefania Raimondo, Janusz Rak, Marcel I Ramirez, Graça Raposo, Morsi S Rayyan, Neta Regev-Rudzki, Franz L Ricklefs, Paul D Robbins, David D Roberts, Silvia C Rodrigues, Eva Rohde, Sophie Rome, Kasper MA Rouschop, Aurelia Rughetti, Ashley E Russell, Paula Saá, Susmita Sahoo, Edison Salas-Huenuleo, Catherine Sánchez, Julie A Saugstad, Meike J Saul, Raymond M Schiffelers, Raphael Schneider, Tine Hiorth Schøyen, Aaron Scott, Eriomina Shahaj, Shivani Sharma, Olga Shatnyeva, Faezeh Shekari, Ganesh Vilas Shelke, Ashok K Shetty, Kiyotaka Shiba, Pia R-M Siljander, Andreia M Silva, Agata Skowronek, Orman L Snyder, Rodrigo Pedro Soares, Barbara W Sódar, Carolina Soekmadji, Javier Sotillo, Philip D Stahl, Willem Stoorvogel, Shannon L Stott, Erwin F Strasser, Simon Swift, Hidetoshi Tahara, Muneesh Tewari, Kate Timms, Swasti Tiwari, Rochelle Tixeira, Mercedes Tkach, Wei Seong Toh, Richard Tomasini, Ana Claudia Torrecilhas, Juan Pablo Tosar, Vasilis Toxavidis, Lorena Urbanelli, Pieter Vader, Bas WM van Balkom, Susanne G van der Grein, Jan Van Deun, Martijn JC van Herwijnen, Kendall Van Keuren-Jensen, Guillaume van Niel, Martin E van Royen, Andre J van Wijnen, M Helena Vasconcelos, Ivan J Vechetti, Tiago D Veit, Laura J Vella, Émilie Velot, Frederik J Verweij, Beate Vestad, Jose L Viñas, Tamás Visnovitz, Krisztina V Vukman, Jessica Wahlgren, Dionysios C Watson, Marca HM Wauben, Alissa Weaver, Jason P Webber, Viktoria Weber, Ann M Wehman, Daniel J Weiss, Joshua A Welsh, Sebastian Wendt, Asa M Wheelock, Zoltán Wiener, Leonie Witte, Joy Wolfram, Angeliki Xagorari, Patricia Xander, Jing Xu, Xiaomei Yan, María Yáñez-Mó, Hang Yin, Yuana Yuana, Valentina Zappulli, Jana Zarubova, Vytautas Žėkas, Jian-ye Zhang, Zezhou Zhao, Lei Zheng, Alexander R Zheutlin, Antje M Zickler, Pascale Zimmermann, Angela M Zivkovic, Davide Zocco, Ewa K Zuba-Surma
Publikováno v:
Journal of Extracellular Vesicles, Vol 7, Iss 1 (2018)
The last decade has seen a sharp increase in the number of scientific publications describing physiological and pathological functions of extracellular vesicles (EVs), a collective term covering various subtypes of cell-released, membranous structure
Externí odkaz:
https://doaj.org/article/6dfd3309492545d6af940b9b91fdda8e
Autor:
Sharon M. Gorski, Marcel B. Bally, Donald T. Yapp, Karen Gelmon, Sherry A. Weppler, Lindsay DeVorkin, Nancy E. Go, Amy Leung, Namal Abeysundara, Jing Xu, Wieslawa H. Dragowska, Svetlana Bortnik, Suganthi Chittaranjan
Purpose: Triple-negative breast cancers (TNBC) are defined by a lack of expression of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (ERBB2/HER2). Although initially responsive to chemotherapy, most r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d2ccabdd84a4b612d09df84074731e7
https://doi.org/10.1158/1078-0432.c.6522399.v1
https://doi.org/10.1158/1078-0432.c.6522399.v1
Autor:
Sharon M. Gorski, Marcel B. Bally, Donald T. Yapp, Karen Gelmon, Sherry A. Weppler, Lindsay DeVorkin, Nancy E. Go, Amy Leung, Namal Abeysundara, Jing Xu, Wieslawa H. Dragowska, Svetlana Bortnik, Suganthi Chittaranjan
Establishment of saturation levels of BAF for MDA-MB-231, R8, SUM159PT and R75.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b124e795e655db3a96ef0db5d026152
https://doi.org/10.1158/1078-0432.22452174
https://doi.org/10.1158/1078-0432.22452174
Autor:
Sharon M. Gorski, Marcel B. Bally, Donald T. Yapp, Karen Gelmon, Sherry A. Weppler, Lindsay DeVorkin, Nancy E. Go, Amy Leung, Namal Abeysundara, Jing Xu, Wieslawa H. Dragowska, Svetlana Bortnik, Suganthi Chittaranjan
Detailed description of Alamar blue assay, QRT-PCR, transfections, siRNA, western blot analyses, autophagic flux assay, IHC, and associated references.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24dc2cc3de95cbde0223137d80ba7577
https://doi.org/10.1158/1078-0432.22452162.v1
https://doi.org/10.1158/1078-0432.22452162.v1
Autor:
Sharon M. Gorski, Marcel B. Bally, Donald T. Yapp, Karen Gelmon, Sherry A. Weppler, Lindsay DeVorkin, Nancy E. Go, Amy Leung, Namal Abeysundara, Jing Xu, Wieslawa H. Dragowska, Svetlana Bortnik, Suganthi Chittaranjan
Inhibitory activity of anthracyclines and their analogs on sensitive and resistant TNBC cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e21a090916a3c5552b5ec5a4b1d9793
https://doi.org/10.1158/1078-0432.22452159
https://doi.org/10.1158/1078-0432.22452159
Autor:
Sharon M. Gorski, Marcel B. Bally, Donald T. Yapp, Karen Gelmon, Sherry A. Weppler, Lindsay DeVorkin, Nancy E. Go, Amy Leung, Namal Abeysundara, Jing Xu, Wieslawa H. Dragowska, Svetlana Bortnik, Suganthi Chittaranjan
Supplementary Figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7df20fbd07f78ab1a3f939ca5ee4a723
https://doi.org/10.1158/1078-0432.22452165.v1
https://doi.org/10.1158/1078-0432.22452165.v1
Autor:
Sharon M. Gorski, Marcel B. Bally, Donald T. Yapp, Karen Gelmon, Sherry A. Weppler, Lindsay DeVorkin, Nancy E. Go, Amy Leung, Namal Abeysundara, Jing Xu, Wieslawa H. Dragowska, Svetlana Bortnik, Suganthi Chittaranjan
Pharmacologic inhibition of autophagy sensitizes EPI-sensitive BT549 and EPI-resistant R75 TNBC cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763d47feaaefc18c1405fc33f975614c
https://doi.org/10.1158/1078-0432.22452168.v1
https://doi.org/10.1158/1078-0432.22452168.v1