Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Sharon M. Crary"'
Autor:
Franklin L. Zhong, Thomas R. Cech, Neelam Giri, Sharon M. Crary, Steven E. Artandi, Luis F.Z. Batista, Marius Wernig, Matthew F. Pech, Renee A. Reijo Pera, Sharon A. Savage, Ha Nam Nguyen, Athena M. Cherry, Kathleen T. Xie, Vittorio Sebastiano, Arthur J. Zaug, Jinkuk Choi, Blanche P. Alter
Publikováno v:
Nature. 474:399-402
Dyskeratosis congenita, a disease characterized by defective maintenance of blood, pulmonary and epidermal tissues, is caused by defects in genes required for telomere homeostasis. Short telomeres are thought to cause signs of the disease in mouse mo
Autor:
Martha L. Wilkinson, Jane E. Jackman, Eric M. Phizicky, Elizabeth J. Grayhack, Sharon M. Crary
Publikováno v:
RNA. 13:404-413
The methylation of the ribose 2′-OH of RNA occurs widely in nature and in all stable RNAs and occurs at five positions in yeast tRNA. 2′-O-methylation of tRNA at position 4 is interesting because it occurs in the acceptor stem (which is normally
Publikováno v:
Virology. 306(2):210-218
Thermodynamic modeling of Ebola viral RNA predicts the formation of RNA stem-loop structures at the 3′ and 5′ termini and panhandle structures between the termini of the genomic (or antigenomic) RNAs. Sequence analysis showed a high degree of ide
Publikováno v:
Proceedings of the National Academy of Sciences. 95:15212-15217
The protein component of ribonuclease P (RNase P) binds to the RNA subunit, forming a functional ribonucleoprotein complex in vivo and enhancing the affinity of the precursor tRNA (pre-tRNA) substrate. Photocrosslinking experiments with pre-tRNA boun
Publikováno v:
Biochemistry. 37:9409-9416
Ribonuclease P (RNase P) is a ribonucleoprotein complex that catalyzes the formation of the mature 5' end of tRNA. To investigate the role of the protein component in enhancing the affinity of Bacillus subtilis RNase P for substrate (Kurz, J. C., Nir
Publikováno v:
Nucleic Acids Research
Mutations in the gene for telomerase reverse transcriptase (hTERT) are associated with diseases including dyskeratosis congenita, aplastic anemia, pulmonary fibrosis and cancer. Understanding the molecular basis of these telomerase-associated disease
Autor:
Sharon M. Crary, Pierre E. Rollin, Thomas G. Ksiazek, Felix Kaducu, Jonathan S. Towner, Anthony Sanchez, Daniel G. Bausch, William F. Lee, Christina F. Spiropoulou, Robert Downing, Mathew Lukwiya, Martin J. Vincent, Stuart T. Nichol
Publikováno v:
Journal of Virology
The largest outbreak on record of Ebola hemorrhagic fever (EHF) occurred in Uganda from August 2000 to January 2001. The outbreak was centered in the Gulu district of northern Uganda, with secondary transmission to other districts. After the initial