Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Sharon M Louie"'
Autor:
Avner Adini, Victoria H. Ko, Mark Puder, Sharon M. Louie, Carla F. Kim, Joseph Baron, Benjamin D. Matthews
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Acute Respiratory Distress Syndrome (ARDS) and Ulcerative Colitis (UC) are each characterized by tissue damage and uncontrolled inflammation. Neutrophils and other inflammatory cells play a primary role in disease progression by acutely responding to
Externí odkaz:
https://doaj.org/article/339d572eadb94e5ba9fa0e9203652e8e
Autor:
Maxwell A. Ruby, Julie Massart, Devon M. Hunerdosse, Milena Schönke, Jorge C. Correia, Sharon M. Louie, Jorge L. Ruas, Erik Näslund, Daniel K. Nomura, Juleen R. Zierath
Publikováno v:
Cell Reports, Vol 18, Iss 3, Pp 636-646 (2017)
Serine hydrolases are a large family of multifunctional enzymes known to influence obesity. Here, we performed activity-based protein profiling to assess the functional level of serine hydrolases in liver biopsies from lean and obese humans in order
Externí odkaz:
https://doaj.org/article/aa11d88b9e6d4a64a80f36f80d98b06d
Publikováno v:
Am J Respir Cell Mol Biol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e21043c75dca436fd100aa404018670
https://doi.org/10.1165/rcmb.2021-0263le
https://doi.org/10.1165/rcmb.2021-0263le
Autor:
Daniel I. Benjamin, Pieter Both, Joel S. Benjamin, Christopher W. Nutter, Jenna H. Tan, Jengmin Kang, Leo A. Machado, Julian D. D. Klein, Antoine de Morree, Soochi Kim, Ling Liu, Hunter Dulay, Ludovica Feraboli, Sharon M Louie, Daniel K Nomura, Thomas A. Rando
Publikováno v:
Cell metabolism, vol 34, iss 6
Cell Metab
Cell Metab
SummaryShort-term fasting is beneficial for the regeneration of multiple tissue types. However, the effects of fasting on muscle regeneration are largely unknown. Here we report that fasting slows muscle repair both immediately after the conclusion o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a753afd6c9b9e6c72eab9118edd096f
https://escholarship.org/uc/item/19v2p64p
https://escholarship.org/uc/item/19v2p64p
Autor:
Suneil K. Koliwad, Rachel T. Cheang, Frederic Woodward Hopf, Xiaoyi Yuan, Allison W. Xu, Matthew T Maier, Sharon M. Louie, Scott A. Wegner, Anna Vilhelmsson, Ernie Yulyaningsih, Maria Ibars, Daniel K. Nomura, Holger K. Eltzschig, Luz Perez
Publikováno v:
Am J Physiol Endocrinol Metab
Excessive alcohol consumption, including binge drinking, is a common cause of fatty liver disease. Binge drinking rapidly induces hepatic steatosis, an early step in the pathogenesis of chronic liver injury. Despite its prevalence, the process by whi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec25308d02692a6ad17bf515a4a9ba5e
https://doi.org/10.1152/ajpendo.00218.2019
https://doi.org/10.1152/ajpendo.00218.2019
Autor:
Daniel I. Benjamin, Jamie O. Brett, Pieter Both, Joel S. Benjamin, Heather L. Ishak, Jengmin Kang, Soochi Kim, Mingyu Chung, Marina Arjona, Christopher W. Nutter, Jenna H. Tan, Ananya K. Krishnan, Hunter Dulay, Sharon M. Louie, Antoine de Morree, Daniel K. Nomura, Thomas A. Rando
Publikováno v:
Cell Metabolism. 35:472-486.e6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fea0fe8b5db3b6819fc5020f33f94c52
https://doi.org/10.1016/j.cmet.2023.02.001
https://doi.org/10.1016/j.cmet.2023.02.001
Autor:
Carla F. Kim, Ryan M. Hekman, Benjamin C. Blum, William D. Wallace, Eileen Fung, Steven M. Dubinett, Roderick T. Bronson, Preetida J. Bhetariya, Sharon M. Louie, Carlos Villacorta-Martin, Antonella F.M. Dost, Andrew Emili, Jane Yanagawa, Julio Sainz de Aja, Dar Heinze, Marall Vedaie, Gustavo Mostoslavsky, Gregory A. Fishbein, Mary E. Piper, Julian H. Kwan, Samuel P. Rowbotham, Linh M. Tran, Kostyantyn Krysan, Jessie Huang, Aaron L. Moye, Darrell N. Kotton
Publikováno v:
Cell stem cell, vol 27, iss 4
Cell Stem Cell
Cell Stem Cell
Summary Mutant KRAS is a common driver in epithelial cancers. Nevertheless, molecular changes occurring early after activation of oncogenic KRAS in epithelial cells remain poorly understood. We compared transcriptional changes at single-cell resoluti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc7ee7e1f223f34dcae0593d2b9c2b20
https://escholarship.org/uc/item/59d4j07r
https://escholarship.org/uc/item/59d4j07r
Autor:
Sharon M. Louie, Aaron L. Moye, Irene G. Wong, Emery Lu, Andrea Shehaj, Carolina Garcia-de-Alba, Erhan Ararat, Benjamin A. Raby, Bao Lu, Margherita Paschini, Roderick T. Bronson, Carla F. Kim
Publikováno v:
Cell Reports. 39:110662
Lung progenitor cells are crucial for regeneration following injury, yet it is unclear whether lung progenitor cells can be functionally engrafted after transplantation. We transplanted organoid cells derived from alveolar type II (AT2) cells enriche
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eebf00b0681ff8107da61d1c9153b937
https://doi.org/10.1016/j.celrep.2022.110662
https://doi.org/10.1016/j.celrep.2022.110662
Autor:
Allison W. Xu, Matthew T Maier, Eirini Vagena, Anna Vilhelmsson, Daniel K. Nomura, Suneil K. Koliwad, Sharon M. Louie
Publikováno v:
Endocrinology. 159:2408-2420
Proper regulation of energy metabolism requires neurons in the central nervous system to respond dynamically to signals that reflect the body’s energy reserve, and one such signal is leptin. Agouti-related protein (AgRP) is a hypothalamic neuropept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11696b7a78ac26a7aa71712eed3735bb
https://doi.org/10.1210/en.2018-00040
https://doi.org/10.1210/en.2018-00040
Autor:
Xuntian Jiang, Roberto Zoncu, Daniel K. Nomura, Ofer Moldavski, Laurel Mydock-McGrane, Daniel S. Ory, McKenna Feltes, Oliver B. Davis, Robert J. van Eijkeren, Rushika M. Perera, Brian M. Castellano, Sharon M. Louie, Douglas F. Covey, Ashley M. Thelen, Reini E. N. van der Welle
Publikováno v:
Science (New York, N.Y.), vol 355, iss 6331
The mechanistic target of rapamycin complex 1 (mTORC1) protein kinase is a master growth regulator that becomes activated at the lysosome in response to nutrient cues. Here, we identify cholesterol, an essential building block for cellular growth, as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a65da3c4ebec37664cd3e27fa1635d
https://doi.org/10.1126/science.aag1417
https://doi.org/10.1126/science.aag1417